Results 201 to 210 of about 4,834 (282)
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng +4 more
wiley +1 more source
Unveiling the Transgalactosylation Switch of a GH42 β‑Galactosidase from the Infant Isolate <i>Bifidobacterium breve</i> DSM20213. [PDF]
Phirom-On K +12 more
europepmc +1 more source
Senolytics and exercise: Dual modalities for rejuvenating muscle
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
Discovery and Preliminary Characterization of Lactose-Transforming Enzymes in Ewingella americana L47: A Genomic, Biochemical, and In Silico Approach. [PDF]
Rivero K +10 more
europepmc +1 more source
Two β-galactosidases from the human isolate Bifidobacterium breve DSM 20213: molecular cloning and expression, biochemical characterization and synthesis of galacto-oligosaccharides. [PDF]
Arreola SL +7 more
europepmc +1 more source
ABSTRACT Background Ceramides have garnered considerable attention as pro‐aging bioactive lipids implicated in both metabolic dysfunction and musculoskeletal decline. Among these, C18:0 and C24:1 ceramides may play a role in the pathophysiology of sarcopenia, a key manifestation of age‐related deterioration.
So Jeong Park +15 more
wiley +1 more source
Water loss is a key factor affecting the postharvest quality and shelf life of blueberries, and storage conditions (humidity and time) play an important role in regulating water retention capacity of stored berries. This study aims to explore the variation of moisture content (MC) in blueberries under different storage humidity and storage time ...
RunKai Wang +3 more
wiley +1 more source
Abstract Zinc finger proteins are essential for the proper functioning of eukaryotic organisms, while their artificial variants can be used in cancer therapy or gene editing via their specific DNA recognition. Zn(II) binding is indispensable for the structural integrity of zinc fingers.
Bálint Hajdu +8 more
wiley +1 more source
Molecular Structure of Endotoxins from Gram-negative Marine Bacteria: An Update (review) [PDF]
A. Molinaro +5 more
core +1 more source
Pitfalls and missing links in current understanding of 4D genomes
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley +1 more source

