Results 131 to 140 of about 2,563,124 (253)

Cellulose and pectin alter intestinal β-glucuronidase (EC 3.2.1.31) in the rat

, 1985
Groups of rats were given a fibre-free diet containing none or one of the three fibre components: pectin, cellulose or galactomannan. After feeding for 16 weeks, total protein level and β-glucuronidase (EC 3.2.1.31) activity in the contents and mucosa of
Lindop, R, TasmanJones, C, Thomsen, LL, Lee, SP   +3 more
core  

Beyond biologic sex: Exploratory insights into the heterogeneity of hormonal and contextual drivers of periodontal and peri‐implant outcomes

Periodontology 2000, EarlyView.
Abstract Background Periodontal and peri‐implant diseases are multifactorial inflammatory conditions influenced by microbial, host, hormonal, genetic, and behavioral factors. Although sex‐based differences in immune and inflammatory responses are well recognized in medicine, the extent to which biologic sex and hormonal status influence the prevalence,
Caitlin Neapole, Mark Gettas, Roberto Farina, Yvonne Hernandez‐Kapila   +3 more
wiley   +1 more source

DETERMINATION OF β-GLUCURONIDASE IN MICROGRAM QUANTITIES OF TISSUE AND ITS DISTRIBUTION IN THE COW ADRENAL

, 1953
The procedure of Talalay, Fishman and Huggins was adapted to the determination of β-glucuronidase activity in microgram quantities of tissue. The quantitative histological distribution of β-glucuronidase activity in the cow adrenal was studied, and it ...
LEE W. WATTENBERG, DAVID GLICK
core   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

Advanced Science, Volume 13, Issue 55, 5 October 2026.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

NAPHTHOL AS-BI β-d-GLUCOSIDURONIC ACID; ITS SYNTHESIS AND SUITABILITY AS A SUBSTRATE FOR β-GLUCURONIDASE

, 1964
1. Naphthol AS-BI β-d-glucosiduronic acid has been prepared by first reacting potassiumnaphtholate AS-BI with acetobromomethyl glucuronate in absolute alcohol and then by removing the protecting acetyl and methyl groups with barium hydroxide and ...
C. ANSTISS, WILLIAM H. FISHMAN, YASUO NAKAJIMA, SIDNEY GREEN   +3 more
core   +1 more source

Extracellularly Activatable Conjugates of RGD Peptidomimetics and Cryptophycin for αVβ3‐Targeted Cancer Therapy

Chemistry – A European Journal, Volume 32, Issue 37, 1 October 2026.
Integrin αVβ3‐targeting small‐molecule drug conjugates (SMDCs) were synthesized by conjugating a cryptophycin payload through a neutrophil elastase‐cleavable NPV‐PABC linker. RGD peptidomimetic and linker epimers served as controls for targeting and enzymatic cleavage, and the resulting conjugates displayed subnanomolar cytotoxicity in vitro.
Dominic Seißenschmidt, Henriette Hartung, Jonah Kammer, Norbert Sewald   +3 more
wiley   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 871-889, October 2026.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Gallstone formation and hepatobiliary tumour risk: Clinical implications of the bile acid–gut microbiota axis

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Irregular dietary patterns (e.g., late breakfast, reduced meal frequency) upregulate the bai gene cluster by disrupting cholecystokinin (CCK) release rhythms and gut microbiota circadian rhythms, leading to increased production of secondary bile acids, particularly DCA. High‐carbohydrate dietary patterns increase gallstone risk (OR = 1.329).
Rui Li, Yong Zhang, Kaishuang Cai, Shaojun Deng, Chaofeng Tan, Yunjie Li, Wenjin Liang   +6 more
wiley   +1 more source

Quantification of the Carboxylated LGD‐4033 Long‐Term Metabolite in Human Micro‐Dose Excretion Study Urine Samples

Drug Testing and Analysis, Volume 18, Issue 10, Page 1321-1327, October 2026.
A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou, Sebastian Marcel Schröder, Jasmin Thelen, Linus Korsmeier, Sven Guddat, Christian Görgens, Andreas Thomas, Mario Thevis   +7 more
wiley   +1 more source

Enhanced In Situ Detection of β-Glucuronidase Activity in Murine Tissue

, 1999
We outline here a protocol for high-resolution in situ localization of β-glucuronidase in murine tissues processed in glycol methacrylate (GMA). Murine tissues were first stained with 5-bromo-4-chloro-3-indolyl-β-D-glucuronic acid (x-gluc), followed by ...
Donald G. Phinney, Gene C. Kopen, Darwin J. Prockop   +2 more
core   +1 more source