Results 211 to 220 of about 2,563,124 (253)

Enhancing stability and by-product tolerance of β-glucuronidase based on magnetic cross-linked enzyme aggregates.

Colloids and Surfaces B: Biointerfaces, 2021
β-glucuronidase is an important catalyst which is highly specific for β-glucuronides. Here, we constructed magnetic cross-linking β-glucuronidase aggregates (MCLEAs) to for the production of glycyrrhetinic acid (GA).
B. Wei, Fang Liu, Xiaojie Liu, Leiyu Cheng, Qi-Peng Yuan, Hui-Ling Gao, Hao Liang   +6 more
semanticscholar   +1 more source

Specific detection ofEscherichia coliandShigellaspecies using fragments of genes coding for β-glucuronidase

FEMS Microbiology Letters, 1990
The occurrence of β-glucuronidase activity, a main characteristic of Escherichia coli and the presence of the uid chromosomal region of E. coli, coding for this enzyme, were tested on representative members of enteric bacteria. DNA hybridization techniques using uid probes and ampplification experiments of uidA gene by the polymerase chain reaction ...
Philippe Cleuziat, Janine Robert-Baudouy
openaire   +1 more source

The α-glucuronidase Agu1 from Schizophyllum commune is a member of a novel glycoside hydrolase family (GH115)

Applied Microbiology and Biotechnology, 2011
Schizophyllum commune produces an α-glucuronidase that is active on polymeric xylan, while the ascomycete α-glucuronidases are only active on xylan oligomers. In this study, we have identified the gene (agu1) encoding this enzyme and confirmed the functionality by overexpression of the gene in S.
Chong, S.-L., Battaglia, E., Coutinho, P.M., Henrissat, B., Tenkanen, Maija, de Vries, R.P.   +5 more
openaire   +3 more sources

Inhibitory Mechanisms of β‐Glucuronidase by Hibiscus syriacus Phenolics: Integrating Computational and Experimental Approaches

ChemistrySelect
Exploring the intricate mechanisms of β‐glucuronidase inhibition is essential to advancing the development of novel therapeutic agents. This study extensively evaluated the inhibitory potential of phenolics from Hibiscus syriacus against β‐glucuronidase ...
H. Alqhtani, Sarah I. Othman, Faris F. Aba Alkhayl, N. Altoom, A. M. Lamsabhi, Emadeldin M. Kamel   +5 more
semanticscholar   +1 more source

Deciphering molecular mechanisms underlying the inhibition of β-glucuronidase by xanthones from Centaurium spicatum.

Bioorganic chemistry (Print)
Herein, we scrutinized the inhibitory potential of five xanthones and a flavonoid, sourced from Centaurium spicatum, against β-glucuronidase activity.
Emadeldin M. Kamel, H. Alqhtani, M. Bin-Jumah, H. Rudayni, Ashraf A. El-Bassuony, Al Mokhtar Lamsabhi   +5 more
semanticscholar   +1 more source

Turn-on fluorescence detection of β-glucuronidase using RhB@MOF-5 as an ultrasensitive nanoprobe

Sensors and Actuators B: Chemical, 2019
β-Glucuronidase (β-GCU) is closely related to the occurrence of multiple diseases, and it has been applied as a biomarker and therapeutic target in clinical diagnosis.
Lan Guo, Yuan Liu, Rong-Mei Kong, Guang Chen, Hao Wang, Xiuli Wang, Lian Xia, Feng-Li Qu   +7 more
semanticscholar   +1 more source

Unraveling molecular mechanisms of β-glucuronidase inhibition by flavonoids from Centaurea scoparia: integrated in silico and in vitro insights

New Journal of Chemistry
Investigating the detailed molecular mechanisms of β-glucuronidase inhibition is critical for pioneering new therapeutic solutions and driving progress in pharmaceutical research.
M. A. Alwaili, Faris F. Aba Alkhayl, H. Rudayni, A. Allam, N. Altoom, A. M. Lamsabhi, Emadeldin M. Kamel   +6 more
semanticscholar   +1 more source

The study of inhibitory effect of natural flavonoids toward β-glucuronidase and interaction of flavonoids with β-glucuronidase.

International Journal of Biological Macromolecules, 2019
β-Glucuronidase plays a vital role in the metabolism of drug and endogenous substance. Herein, we assayed the inhibitory effects of thirty-six flavonoids (1-36) toward β-glucuronidase (Escherichia coli) using the probe reaction of DDAO-glu hydrolysis ...
Chengpeng Sun, Jian-kun Yan, Jing Yi, Xin-Yue Zhang, Zhenlong Yu, Xiao-Kui Huo, Jia-Hao Liang, Jing Ning, Lei Feng, Chao Wang, Bao-Jing Zhang, Xiang-Ge Tian, Lin Zhang, Xiao-Chi Ma   +13 more
semanticscholar   +1 more source

Strategy for effective inhibition of arylsulfatase/β-glucuronidase to prevent deconjugation of sulfate and glucuronide conjugates in wastewater during sample collection and storage.

Science of the Total Environment, 2019
Arylsulfatase and β-glucuronidase are two important enzymes that are responsible for deconjugation of estrogen conjugates. It is important to keep estrogen conjugates intact during sample collection and storage, while the effective inhibition conditions ...
Jun Zhang, Ze-hua Liu, Shu-shu Zhong, Hao Wang, Bamu Caidan, Hua Yin, Z. Dang   +6 more
semanticscholar   +1 more source

TRANSIENT β-GLUCURONIDASE EXPRESSION IN ASPARAGUS PROTOPLASTS FOLLOWING ELECTROPORATION

Acta Horticulturae, 1999
C. Guangyu, A.J. Conner, A.G. Fautrier, R.J. Field   +3 more
openaire   +1 more source