Results 121 to 130 of about 898,544 (258)
The Lactamase Engineering Database: a critical survey of TEM sequences in public databases
BMC Genomics, 2009 Background TEM β-lactamases are the main cause for resistance against β-lactam antibiotics. Sequence information about TEM β-lactamases is mainly found in the NCBI peptide database and TEM mutation table at http://www.lahey.org/Studies/temtable.asp ...
Pleiss Jürgen, Bös Fabian, Thai Quan
doaj +1 more source
, 2017 Additional file 2: Table S2. Antimicrobial susceptibility profile of S. flexneri SP1 recovered from a patient with diarrhea.
Shen, Ping +10 more
openaire +1 more source
Electrochemical sensor for the detection of serine β-lactamase catalytic activity
Chimica Techno ActaA new approach is proposed based on the use of electrodes modified with carbon nanomaterials to determine enzymatic activity and screening for inhibitors of serine β-lactamases such as extended spectrum β-lactamases (ESBLs). These enzymes are responsible
Victoria V. Shumyantseva +4 more
doaj +1 more source
Novel and emerging antimicrobial strategies in the management of oral infections
Periodontology 2000, EarlyView.Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley +1 more source
The mechanisms of catalysis by β-lactamases
, 2012 In this chapter, the catalytic mechanisms of β-lactamases are discussed in detail. After an introduction on the reactivity of compounds containing the the β-lactam ring, each class of β-lactamases is reviewed and analysed in terms of essential residues ...
Fink, Anthony L., Page, Michael
core +2 more sources
, 2017 Additional file 1: Table S1. Summary of S. flexneri strain SP1 genome.
Shen, Ping +10 more
openaire +1 more source
Transplant Infectious Disease, EarlyView.Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti +6 more
wiley +1 more source
Zinc-Bound Thiolate−Disulfide Exchange: A Strategy for Inhibiting Metallo-β-lactamases
, 2016 The mononuclear zinc thiolate complexes [(TpPhMe)Zn(S-R)], where TpPhMe is hydrotris((3-methyl-5-phenyl)pyrazolyl)borate and (S-R) is benzyl thiolate, 4-nitrophenylthiolate, 4-trifluoromethylphenylthiolate, 4-chlorophenylthiolate, phenylthiolate, 2 ...
Heidi Boerzel (2967024) +4 more
core +2 more sources
"Golden Era of Antibiotics" - Coming to an end !!!
SRM Journal of Research in Dental Sciences, 2012 Resistance to antibiotics is increasing at an alarming rate. This is due to superbugs, producing heterogenous groups of enzymes, β-lactamases which inactivate β-lactam antibiotics and others as well.
V Vinodhini +4 more
doaj
Analysis of the plasmid content of three β-lactamase-producingNeisseria gonorrhoeaestrains [PDF]
FEMS Microbiology Letters, 1982 Olivier Fayet +2 more
openaire +1 more source