Results 71 to 80 of about 62,950 (317)

Investigation on some Beta- lactamase enzym types in Rhizobium leguminosarum biovar viciae [PDF]

مجلة التربية والعلم, 2009
Detection of β–lactamases was conducted in Rhizobium leguminosarum biovar viciae isolated from root nodules of Vicia faba L.. Acidimetric method was used to detect the occurrence of β–lactamases in general, the isolate gave a positive result.
Mohammed Ibrahem Altee, Mahmoud Zakei Alhaso   +1 more
doaj   +1 more source

Complete sequence of the IncA/C 1 plasmid pCf587 carrying bla PER-2 from citrobacter freundii [PDF]

, 2018
The bla PER-2 -harboring plasmid pCf587 (191,541 bp) belongs to lineage IncA/C 1 and is closely related to pRA1. It contains a large resistance island including the bla PER-2 gene between two copies of ISKox2-like elements, the toxin-antitoxin module ...
Dabos, Laura, Girlich, Delphine, Gutkind, Gabriel Osvaldo, Naas, Thierry, Power, Pablo, Ruggiero, Melina   +5 more
core   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

A review of SHV extended-spectrum β-lactamases: neglected yet ubiquitous

Frontiers in Microbiology, 2016
β-lactamases are the primary cause of resistance to β-lactams among members of the family Enterobacteriaceae. SHV enzymes have emerged in Enterobacteriaceae causing infections in health care in the last decades of the 20st century, and they are now ...
Apostolos Liakopoulos, Dik Mevius, Dik Mevius, Daniela Ceccarelli   +3 more
doaj   +1 more source

Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4 [PDF]

, 2018
A putative fosA gene in Kluyvera georgiana 14751 showed 99% nucleotide identity with plasmid-encoded fosA4. Due to a single-nucleotide insertion translating to a truncated protein, K. georgiana 14751 fosA does not confer fosfomycin resistance.
Ghiglione, Barbara, Gutkind, Gabriel Osvaldo, Naas, Thierry, Power, Pablo, Rodriguez, Maria Margarita   +4 more
core   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Altering Enzymatic Activity: Recruitment of Carboxypeptidase Activity into an RTEM β-Lactamase/Penicillin-Binding Protein 5 Chimera [PDF]

, 1990
The D-Ala-D-Ala carboxypeptidases/transpeptidases (penicillin-binding proteins, PBPs) share considerable structural homology with class A β-lactamases (EC 3.5.2.6), although these β-lactamases have no observable D-Ala-D-Ala carboxypeptidase activity ...
Chang, Yie-Hwa, Labgold, Marc R., Richards, John H.   +2 more
core  

QM/MM simulations as an assay for carbapenemase activity in class A β-lactamases [PDF]

, 2014
Carbapenemases are distinguished from carbapenem-inhibited β-lactamases with a protocol involving QM/MM free energy simulations of acyl–enzyme deacylation, requiring only the enzyme 3D structure as input.
Chudyk, Ewa I, Jones, Charlotte, Limb, Michael A L, Mulholland, Adrian J, Spencer, James, van der Kamp, Marc W   +5 more
core   +2 more sources

Antibacterial Activity of Heteropolytungstates Against Proteus mirabilis

European Journal of Inorganic Chemistry, EarlyView.
We investigated the in vitro antibacterial activity of several heteropolytungstates against P. mirabilis, a drug‐resistant pathogen. All tested polyanions inhibited bacterial growth, with the Preyssler–Pope–Jeannin polyanion P5W30 exhibiting the highest activity (MIC = 0.78 mg/mL).
Nour El Ghouch, Ahmad Asaad, Rana El Hajj, Sahar Khandan, Matthias S. Ullrich, Ulrich Kortz   +5 more
wiley   +1 more source

Phenotypic detection of Metallo- and AmpC β-lactamases producing strains of P. aeruginosa in the state of Himachal Pradesh (India) [PDF]

Al Ameen Journal of Medical Sciences, 2015
Background: A prospective study was undertaken to detect metallo-β-lactamases (MBLs) and AmpC β-lactamases in Pseudomonas aeruginosa isolates recovered from patients at Indira Gandhi Medical College, Shimla (H.P).
Naveen Minhas, Prakash Chand Sharma
doaj