Results 51 to 60 of about 28,374 (228)

Expanding the β‐Lactamase Family in the Human Microbiome

Advanced Science
β‐lactams, the most common antibiotics globally, have resistance primarily determined by β‐lactamases. Human microbiota and β‐lactams influence mutually; however, β‐lactamase variety and abundance in the human microbiome remain partially understood. This
Baolei Jia, Ju Hye Baek, Jae Kyeong Lee, Ying Sun, Kyung Hyun Kim, Ji Young Jung, Che Ok Jeon   +6 more
doaj   +1 more source

Carbapenem-Resistant Klebsiella pneumoniae in Large Public Acute-Care Healthcare System, New York, New York, USA, 2016–2022

Emerging Infectious Diseases, 2023
Controlling the spread of carbapenem-resistant Enterobacterales is a global priority. Using National Healthcare Safety Network data, we characterized the changing epidemiology of carbapenem-resistant Klebsiella pneumoniae (CRKP) in a large public health
Jennifer Lee, Subin Sunny, Elizabeth Nazarian, Mary Fornek, Marie Abdallah, Briana Episcopia, Marie-Claire Rowlinson, John Quale   +7 more
doaj   +1 more source

MOESM2 of Molecular characterization of β-lactamase genes in clinical isolates of carbapenem-resistant Acinetobacter baumannii

, 2017
Additional file 2: Table S2. Primer sequences used for A. baumannii in present study.
Raible, Kevin, Sen, Bhaswati, Law, Nancy, Bias, Tiffany, Emery, Christopher, Ehrlich, Garth, Joshi, Suresh   +6 more
openaire   +1 more source

Classification of Beta-lactamases and penicillin binding proteins using ligand-centric network models. [PDF]

PLoS ONE, 2015
β-lactamase mediated antibiotic resistance is an important health issue and the discovery of new β-lactam type antibiotics or β-lactamase inhibitors is an area of intense research.
Hakime Öztürk, Elif Ozkirimli, Arzucan Özgür   +2 more
doaj   +1 more source

The Role of Hydrophobic Nodes in the Dynamics of Class A β-Lactamases

Frontiers in Microbiology, 2021
Class A β-lactamases are known for being able to rapidly gain broad spectrum catalytic efficiency against most β-lactamase inhibitor combinations as a result of elusively minor point mutations.
Edgar Olehnovics, Junqi Yin, Adrià Pérez, Gianni De Fabritiis, Gianni De Fabritiis, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, Robert A. Bonomo, Debsindhu Bhowmik, Shozeb Haider   +13 more
doaj   +1 more source

A review of SHV extended-spectrum β-lactamases: neglected yet ubiquitous

Frontiers in Microbiology, 2016
β-lactamases are the primary cause of resistance to β-lactams among members of the family Enterobacteriaceae. SHV enzymes have emerged in Enterobacteriaceae causing infections in health care in the last decades of the 20st century, and they are now ...
Apostolos Liakopoulos, Dik Mevius, Dik Mevius, Daniela Ceccarelli   +3 more
doaj   +1 more source

Investigation on some Beta- lactamase enzym types in Rhizobium leguminosarum biovar viciae [PDF]

مجلة التربية والعلم, 2009
Detection of β–lactamases was conducted in Rhizobium leguminosarum biovar viciae isolated from root nodules of Vicia faba L.. Acidimetric method was used to detect the occurrence of β–lactamases in general, the isolate gave a positive result.
Mohammed Ibrahem Altee, Mahmoud Zakei Alhaso   +1 more
doaj   +1 more source

Integrating One Health to Mitigate the Emergence and Spread of Antimicrobial Resistance in Livestock and Aquaculture

Animal Research and One Health, EarlyView.
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali, Delower Hossain, Ridwan Olamilekan Adesola, Anum Hanif, Shamsaldeen Ibrahim Saeed, Muhammad Abdul Mannan, Anoar Jamai Masroure, Kazi Estieque Alam, Md Kamal Hossain, Sabiha Zarin Tasnim Bristi, Md Jisan Ahmed   +10 more
wiley   +1 more source

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

Frontiers in Pharmacology
The development of resistance to carbapenems in Klebsiella pneumoniae due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems are the last-resort drugs used for treating severe infections of extended ...
Wesam H. Abdulaal, Nabil A. Alhakamy, Nabil A. Alhakamy, Nabil A. Alhakamy, Amer H. Asseri, Amer H. Asseri, Mohamed F. Radwan, Tarek S. Ibrahim, Solomon Z. Okbazghi, Hisham A. Abbas, Basem Mansour, Aly A. Shoun, Wael A. H. Hegazy, Wael A. H. Hegazy, Mahmoud Saad Abdel-Halim   +14 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source