Results 1 to 10 of about 24,598 (183)

Directed carbapenemase testing is no longer just for Enterobacterales: cost, labor, and workflow assessment of expanding carbapenemase testing to carbapenem-resistant P. aeruginosa

Emerging Microbes and Infections, 2023
Molecular carbapenem-resistance testing, such as for the presence of carbapenemases genes, is commonly implemented for the detection of carbapenemase-producing Enterobacterales. Carbapenemase-producing P.
Fred C Tenover, David Nicolau, Christian M Gill   +2 more
exaly   +3 more sources

An improved method for rapid detection and characterization of carbapenemase-producing Enterobacterales directly from positive blood cultures: dBLIMplus [PDF]

Microbiology Spectrum
In this study, a new phenotypic method “dBLIMplus” performed by using combination disks for both detection of carbapenemase activity and determination of the carbapenemase enzyme of carbapenemase-producing Enterobacterales strains from positive blood ...
Tugba Ayvalik Ruzgarkesen, Emel Sesli Cetin, Mumtaz Cem Sirin, Buket Aridogan   +3 more
doaj   +2 more sources

The shift from “MIC-Only” back to carbapenemase testing among carbapenem-resistant Enterobacterales: what clinical laboratories need to know about updated CLSI guidance [PDF]

Journal of Clinical Microbiology
Carbapenem-resistant organisms (CROs) pose a major threat to global health due to limited therapeutic options and their capacity for rapid dissemination.
Patricia J. Simner
doaj   +2 more sources

Phenotypic and genotypic characterization of carbapenem resistant Klebsiella pneumoniae clinical isolates from Damietta, Egypt [PDF]

BMC Microbiology
Background The notable emergence of carbapenemase production is a critical problem threatening human health worldwide. Hence, this study aimed to monitor the prevalence of carbapenemase-producing Klebsiella pneumoniae in Damietta, Egypt.
Mohamed I. Abou-Dobara, Ahmed K. A. El-Sayed, Radwa N. Elmaghalawy, Hazem H. Saleh   +3 more
doaj   +2 more sources

Diagnostic Performance of BD Phoenix CPO Detect Panels for Detection and Classification of Carbapenemase-Producing Gram-Negative Bacteria

Microbiology Spectrum, 2023
BD Phoenix CPO Detect panels can identify and classify carbapenemase-producing organisms (CPOs) simultaneously with antimicrobial susceptibility testing (AST) for Gram-negative bacteria.
Mika Murata, Kosuke Kosai, Norihiko Akamatsu, Yumiko Matsuyama, Mitsuharu Oda, Atsushi Wakamatsu, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara   +8 more
doaj   +1 more source

Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE)

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: To describe national trends in testing and detection of carbapenemases produced by carbapenem-resistant Enterobacterales (CRE) and associate testing with culture and facility ...
Margaret A. Fitzpatrick, Katie J. Suda, Swetha Ramanathan, Geneva Wilson, Linda Poggensee, Martin Evans, Makoto M. Jones, Christopher D. Pfeiffer, J. Stacey Klutts, Eli Perencevich, Michael Rubin, Charlesnika T. Evans, for the QUERI CARRIAGE Program   +12 more
doaj   +1 more source

Detection of blaKPC and blaNDM carbapenemase genes among Klebsiella pneumoniae isolates in Addis Ababa, Ethiopia: Dominance of blaNDM.

PLoS ONE, 2022
BackgroundInfections caused by Klebsiella pneumoniae have been difficult to control because of the worldwide emergence of carbapenem-resistant isolates mainly due to carbapenemase production. Information regarding carbapenemase-producing K. pneumoniae is
Tewachew Awoke, Brhanu Teka, Abraham Aseffa, Shemse Sebre, Aminu Seman, Biruk Yeshitela, Tamrat Abebe, Adane Mihret   +7 more
doaj   +1 more source

A Longitudinal Nine-Year Study of the Molecular Epidemiology of Carbapenemase-Producing Enterobacterales Isolated From a Regional Hospital in Taiwan: Predominance of Carbapenemase KPC-2 and OXA-48

Frontiers in Microbiology, 2022
Enterobacterales clinical isolates are now being resistant to clinically achievable concentrations of most commonly used antibiotics that makes treatment of hospitalized patients very challenging.
Tran Thi Thuy Duong, Ya-Min Tsai, Li-Li Wen, Hui-Chuan Chiu, Pek Kee Chen, Tran Thi Dieu Thuy, Pei-Yun Kuo, Jazon Harl Hidrosollo, Shining Wang, Yen-Zhen Zhang, Wei-Hung Lin, Wei-Hung Lin, Ming-Cheng Wang, Ming-Cheng Wang, Cheng-Yen Kao   +14 more
doaj   +1 more source

Carbapenemase genes and mortality in patients with carbapenem-resistant Enterobacterales, Atlanta, Georgia, 2011–2020

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Carbapenemase genes in carbapenem-resistant Enterobacterales (CP-CRE) may be transmitted between patients and bacteria. Reported rates of carbapenemase genes vary widely, and it is unclear whether having a carbapenemase gene portends worse ...
Lucy Witt, Ahmed Babike, Gillian Smith, Sarah Satola, Mary Elizabeth Sexton, Jesse Jacob   +5 more
doaj   +1 more source

A Four-Hour Carbapenem Inactivation Method (CIMB.S) Using Bacillus stearothermophilus as Indicator Strain

Frontiers in Medicine, 2020
Objectives: There is an urgent need for accurate and fast diagnostic tests to identify carbapenemase-producing bacteria. Here we used Bacillus stearothermophilus as an indicator strain in the format of the carbapenem inactivation method (CIM) procedure ...
Ze-Hua Cui, Ze-Hua Cui, Ling Jia, Ling Jia, Lu Han, Lu Han, Tian Tang, Tian Tang, Zi-Xing Zhong, Zi-Xing Zhong, Liang-Xing Fang, Liang-Xing Fang, Wei-Na Ni, Wei-Na Ni, Min-Ge Wang, Min-Ge Wang, Xi-Ran Wang, Xi-Ran Wang, Ya-Hong Liu, Ya-Hong Liu, Ya-Hong Liu, Xiao-Ping Liao, Xiao-Ping Liao, Xiao-Ping Liao, Jian Sun, Jian Sun, Jian Sun   +26 more
doaj   +1 more source