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Molecular carbapenem-resistance testing, such as for the presence of carbapenemases genes, is commonly implemented for the detection of carbapenemase-producing Enterobacterales. Carbapenemase-producing P.
Fred C Tenover +2 more
exaly +3 more sources
The Immaculate Carbapenemase Study [PDF]
Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the
Kenneth S. Thomson
core +3 more sources
Multidrug resistance has been increasing world wide amongst most microrganisms, and adding to increased rate of both hospital and community acquired infections. Of all resistance mechanisms the alarming spread of carbapenemase producers is most worrisome
Iva Chandola +3 more
doaj +2 more sources
Occurrence of ESBL, AmpC-ESBL, and Carbapenemase Producer Organisms in Clinical Specimens: An Observational Prospective Study [PDF]
Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae are the most common Gram-negative bacillus (GNB) isolates from clinical samples.
Rajal Dave, Abhijeet Joshi
doaj +2 more sources
Screening for carbapenemase-producing Enterobacterales is a necessity for hospitals serving high-risk patient populations. Detection methods often incorporate the modified carbapenemase inactivation method (mCIM) test to verify carbapenemase production ...
D. Garrett Brown +6 more
doaj +3 more sources
Can phenotypic methods accurately identify carbapenemase production in Morganellaceae?
AIM: We aimed to evaluate and compare the performance of two chromagenic media (CM) and the carbapenem-inactivation method (CIM) in identifying carbapenemase production in the Morganellaceae members.
Çisem Karaoğlu +3 more
doaj +2 more sources
To Be or Not to Be an OXA-48 Carbapenemase [PDF]
Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems and penicillins with very weak or almost no activity against expanded-spectrum cephalosporins, some ...
Laura Dabos +5 more
openaire +3 more sources
Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
openaire +2 more sources
BD Phoenix CPO Detect panels can identify and classify carbapenemase-producing organisms (CPOs) simultaneously with antimicrobial susceptibility testing (AST) for Gram-negative bacteria.
Mika Murata +8 more
doaj +1 more source
Carbapenemase-Producing Enterobacteriaceae [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) were almost nonexistent up to the 1990s, but are today encountered routinely in hospitals and other healthcare facilities in many countries including the United States. KPC-producing Klebsiella pneumoniae was the first to emerge and spread globally and is endemic in the United States, Israel, Greece, and
Doi, Yohei, Paterson, David L.
openaire +5 more sources

