Results 1 to 10 of about 46,917 (222)

Phenotypic and genotypic characterization of carbapenem resistant Klebsiella pneumoniae clinical isolates from Damietta, Egypt [PDF]

BMC Microbiology
Background The notable emergence of carbapenemase production is a critical problem threatening human health worldwide. Hence, this study aimed to monitor the prevalence of carbapenemase-producing Klebsiella pneumoniae in Damietta, Egypt.
Mohamed I. Abou-Dobara, Ahmed K. A. El-Sayed, Radwa N. Elmaghalawy, Hazem H. Saleh   +3 more
doaj   +2 more sources

The shift from “MIC-Only” back to carbapenemase testing among carbapenem-resistant Enterobacterales: what clinical laboratories need to know about updated CLSI guidance [PDF]

Journal of Clinical Microbiology
Carbapenem-resistant organisms (CROs) pose a major threat to global health due to limited therapeutic options and their capacity for rapid dissemination.
Patricia J. Simner
doaj   +2 more sources

Multicenter Analytical Performance Evaluation of the BD Phoenix NMIC-461 Panel for Carbapenemase Classification and Antimicrobial Susceptibility Testing of Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp. [PDF]

Antibiotics
Objectives: To evaluate the capability of the BD Phoenix NMIC-461 panel in the detection and classification of carbapenemase production and antimicrobial susceptibility testing of 10 antimicrobial agents among Enterobacterales, Pseudomonas aeruginosa ...
Jingjia Zhang, Liying Sun, Ge Zhang, Wei Kang, Tong Wang, Jin Li, Haotian Gao, Qiwen Yang, Kuixia Sun, Qian Wang, Hongli Sun   +10 more
doaj   +2 more sources

Diagnostic Performance of BD Phoenix CPO Detect Panels for Detection and Classification of Carbapenemase-Producing Gram-Negative Bacteria

Microbiology Spectrum, 2023
BD Phoenix CPO Detect panels can identify and classify carbapenemase-producing organisms (CPOs) simultaneously with antimicrobial susceptibility testing (AST) for Gram-negative bacteria.
Mika Murata, Kosuke Kosai, Norihiko Akamatsu, Yumiko Matsuyama, Mitsuharu Oda, Atsushi Wakamatsu, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara   +8 more
doaj   +1 more source

Increased carbapenemase testing following implementation of national VA guidelines for carbapenem-resistant Enterobacterales (CRE)

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: To describe national trends in testing and detection of carbapenemases produced by carbapenem-resistant Enterobacterales (CRE) and associate testing with culture and facility ...
Margaret A. Fitzpatrick, Katie J. Suda, Swetha Ramanathan, Geneva Wilson, Linda Poggensee, Martin Evans, Makoto M. Jones, Christopher D. Pfeiffer, J. Stacey Klutts, Eli Perencevich, Michael Rubin, Charlesnika T. Evans, for the QUERI CARRIAGE Program   +12 more
doaj   +1 more source

Directed carbapenemase testing is no longer just for Enterobacterales: cost, labor, and workflow assessment of expanding carbapenemase testing to carbapenem-resistant P. aeruginosa

Emerging Microbes and Infections, 2023
Molecular carbapenem-resistance testing, such as for the presence of carbapenemases genes, is commonly implemented for the detection of carbapenemase-producing Enterobacterales. Carbapenemase-producing P.
Christian M. Gill, Poonam Rajkotia, Amity L. Roberts, Fred C. Tenover, David P. Nicolau   +4 more
doaj   +1 more source

Detection of blaKPC and blaNDM carbapenemase genes among Klebsiella pneumoniae isolates in Addis Ababa, Ethiopia: Dominance of blaNDM.

PLoS ONE, 2022
BackgroundInfections caused by Klebsiella pneumoniae have been difficult to control because of the worldwide emergence of carbapenem-resistant isolates mainly due to carbapenemase production. Information regarding carbapenemase-producing K. pneumoniae is
Tewachew Awoke, Brhanu Teka, Abraham Aseffa, Shemse Sebre, Aminu Seman, Biruk Yeshitela, Tamrat Abebe, Adane Mihret   +7 more
doaj   +1 more source

A Longitudinal Nine-Year Study of the Molecular Epidemiology of Carbapenemase-Producing Enterobacterales Isolated From a Regional Hospital in Taiwan: Predominance of Carbapenemase KPC-2 and OXA-48

Frontiers in Microbiology, 2022
Enterobacterales clinical isolates are now being resistant to clinically achievable concentrations of most commonly used antibiotics that makes treatment of hospitalized patients very challenging.
Tran Thi Thuy Duong, Ya-Min Tsai, Li-Li Wen, Hui-Chuan Chiu, Pek Kee Chen, Tran Thi Dieu Thuy, Pei-Yun Kuo, Jazon Harl Hidrosollo, Shining Wang, Yen-Zhen Zhang, Wei-Hung Lin, Wei-Hung Lin, Ming-Cheng Wang, Ming-Cheng Wang, Cheng-Yen Kao   +14 more
doaj   +1 more source

Carbapenemase genes and mortality in patients with carbapenem-resistant Enterobacterales, Atlanta, Georgia, 2011–2020

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Background: Carbapenemase genes in carbapenem-resistant Enterobacterales (CP-CRE) may be transmitted between patients and bacteria. Reported rates of carbapenemase genes vary widely, and it is unclear whether having a carbapenemase gene portends worse ...
Lucy Witt, Ahmed Babike, Gillian Smith, Sarah Satola, Mary Elizabeth Sexton, Jesse Jacob   +5 more
doaj   +1 more source

Development of a Two Triplex Real-Time Polymerase Chain Reaction for Rapid Detection of Six Carbapenemase Genes in Enterobacteriaceae [PDF]

Osong Public Health and Research Perspectives, 2020
Objectives Carbapenem resistance is a serious clinical and public health threat. Carbapenemase can confer carbapenem resistance, and most carbapenemase genes are plasmid encoded so resistance can easily spread.
Ji Ae Choi, Song Mee Bae, Jung Wook Kim, Kwang Jun Lee   +3 more
doaj   +1 more source