Results 1 to 10 of about 24,350 (217)
Journal of Biomolecular Structure and Dynamics, 2019 The discovery of NDM-1 and its variants has caused the emergence of antibiotic resistance in the community and hospital setting, causing major concern for health care across the globe.
Divya Gupta +2 more
exaly +4 more sources
First identification of novel NDM carbapenemase, NDM-7, in Escherichia coli in France. [PDF]
PLoS ONE, 2013 BACKGROUND: The NDM-1 carbapenemase has been identified in 2008 in Enterobacteriaceae. Since then, several reports have emphasized its rapid dissemination throughout the world.
Gaelle Cuzon +2 more
doaj +5 more sources
Specific NDM-1 Inhibitor of Isoliquiritin Enhances the Activity of Meropenem against NDM-1-positive Enterobacteriaceae in vitro [PDF]
International Journal of Environmental Research and Public Health, 2020 NDM-1-positive Enterobacteriaceae have caused serious clinical infections, with high mortality rates. Carbapenem was the ultimate expectation for the treatment of such infections in clinical practice.
Yanling Wang, Lining Xia, Xuming Deng
exaly +4 more sources
Frontiers in Microbiology, 2015 Raoultella ornithinolytica YNKP001 and Leclercia adecarboxylata P10164, harboring conjugative plasmids pYNKP001-NDM and pP10164-NDM with determination of complete nucleotide sequences, respectively, were isolated from two different Chinese patients ...
Fengjun Sun, Yefeng Qiu, Peiyuan Xia
exaly +4 more sources
Genomic characterization of an NDM-9-producing Acinetobacter baumannii clinical isolate and role of Glu152Lys substitution in the enhanced cefiderocol hydrolysis of NDM-9 [PDF]
Frontiers in Microbiology, 2023 Here, we characterized the first French NDM-9-producing Acinetobacter baumannii isolate. A. baumannii 13A297, which belonged to the STPas25 (international clone IC7), was highly resistant to β-lactams including cefiderocol (MIC >32 mg/L). Whole genome
Susie Gaillot +16 more
doaj +3 more sources
PHT427 as an effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor restored the susceptibility of meropenem against Enterobacteriaceae producing NDM-1 [PDF]
Frontiers in Microbiology, 2023 IntroductionWith the increasingly serious problem of bacterial drug resistance caused by NDM-1, it is an important strategy to find effective inhibitors to assist β-lactam antibiotic treatment against NDM-1 resistant bacteria.
Xiaohui Li +11 more
doaj +2 more sources
Microbiology Spectrum, 2023 Carbapenem-resistant Klebsiella pneumoniae (CRKP), which harbors the bla NDM plasmid, has been reported extensively and is considered a global threat clinically.
Yunxing Yang +2 more
exaly +3 more sources
Deciphering the Role of V88L Substitution in NDM-24 Metallo-β-Lactamase
Catalysts, 2019 The New Delhi metallo-β-lactamase-1 (NDM-1) is a typical carbapenemase and plays a crucial role in antibiotic-resistance bacterial infection. Phylogenetic analysis, performed on known NDM-variants, classified NDM enzymes in seven clusters.
Liu Zhihai, Liu Dejun, Shen Jianzhong
exaly +2 more sources
Scientific Reports, 2021 Inhibition of the NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome has recently emerged as a promising therapeutic target for several inflammatory diseases.
Sohaib Nizami +9 more
doaj +1 more source
Antibiotic-resistance genes in E. coli strains in GCC countries: A meta-analysis
Saudi Journal of Medicine and Medical Sciences, 2022 Background: Antimicrobial resistance (AMR) in Escherichia coli is an alarming issue worldwide, including in the Gulf Cooperation Council (GCC) countries, yet the prevailing gene patterns have not recently been reviewed.
Khalid Mubarak Bindayna +3 more
doaj +1 more source