Results 21 to 30 of about 24,350 (217)

The First Experience of Combined Use of Cefepime/Sulbactam and Aztreonam in ICU Patients with Nosocomial Infections Caused by Carbapenem-Resistant Gram-Negative Microorganisms Producing Class B and D Carbapenemases

Антибиотики и Химиотерапия, 2023
Background. The difficulties of antibacterial therapy of infections caused by carbapenemase-producing  gram-negative bacteria are associated with limited options for adequate therapy since, in addition to resistance to carbapenems and other beta-lactams ...
M. P. Suvorova, I. N. Sychev, O. V. Ignatenko, E. N. Burmistrova, S. S. Mirzakhamidova, L. V. Fedina, R. M. Vakolyuk, S. V. Yakovlev   +7 more
doaj   +1 more source

The Changing Epidemiology of Carbapenemase-Producing Enterobacterales

Rambam Maimonides Medical Journal, 2022
Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein, Yuval Geffen, Orna Eluk, Sigal Warman, Worood Aboalheja, Tamar Alon, Ibrahim Firan, Mical Paul   +7 more
doaj   +1 more source

Clinical and molecular characterization of NDM-9 and NDM-13 producing multidrug-resistant Escherichia coli strains in China

BMC Microbiology
Objectives The continuous evolution of NDM variants, some of which exhibit enhanced hydrolytic activity, poses a serious public health threat and necessitates ongoing surveillance.
Jia Tao, Gang Li, Zhichen Zhu, Jie Zhu, Wen Wang, Hui Fu, Hua Yv, Bin Shan, Liru Wang, Yiwei Tang, Liang Chen, Hong Du, Wei Jia   +12 more
doaj   +4 more sources

Polyclonal Dissemination of NDM-1- and NDM-9-Producing Escherichia coli and Klebsiella pneumoniae in French Polynesia [PDF]

Antimicrobial Agents and Chemotherapy, 2021
The whole-genome sequencing analysis revealed a polyclonal dissemination of NDM-1 and NDM-9 variants in Escherichia coli ( n  = 20) and Klebsiella pneumoniae ( n  = 2) in Tahiti since 2015 via interspecies transfer of three different
Saoussen Oueslati, Cécile Emeraud, Victor Grosperrin, Marc Levy, Garance Cotellon, Elodie Creton, Lauraine Gauthier, Rémy A. Bonnin, Thierry Naas, Laurent Dortet   +9 more
openaire   +2 more sources

egemenimre/ccsds-ndm: Minor fix for Combined NDM output to KVN

, 2021
Added proper error message to Combined NDM output to ...
Egemen Imre, Tevfik Uyar, Agit
core   +1 more source

The uncertain role of substandard and falsified medicines in the emergence and spread of antimicrobial resistance

Nature Communications, 2023
Approximately 10% of antimicrobials used by humans in low- and middle-income countries are estimated to be substandard or falsified. In addition to their negative impact on morbidity and mortality, they may also be important drivers of antimicrobial ...
Sean Cavany, Stella Nanyonga, Cathrin Hauk, Cherry Lim, Joel Tarning, Benn Sartorius, Christiane Dolecek, Céline Caillet, Paul N. Newton, Ben S. Cooper   +9 more
doaj   +1 more source

egemenimre/ccsds-ndm: Version 2.0

, 2021
This version adds KVN read / write support.
Egemen Imre
core   +1 more source

Genetic heterogeneity and challenges in the management of permanent neonatal diabetes mellitus: A single-centre study from South India

Indian Journal of Endocrinology and Metabolism, 2022
Aim and Objectives: 1. To study the clinical outcome, growth and glycaemic control, 2. To study the frequency and type of genetic mutations. Methods: This is a retrospective study with a review of data of medical records from 2008 till date.
Sophy Korula, Lavanya Ravichandran, Praveen G Paul, Jabasteen Johnson, Aaron Chapla, Sridhar Santhanam, Anna Simon, Sarah Mathai   +7 more
doaj   +1 more source

Tracking inter-institutional spread of NDM and identification of a novel NDM-positive plasmid, pSg1-NDM, using next-generation sequencing approaches [PDF]

Journal of Antimicrobial Chemotherapy, 2016
Owing to gene transposition and plasmid conjugation, New Delhi metallo-β-lactamase (NDM) is typically identified among varied Enterobacteriaceae species and STs. We used WGS to characterize the chromosomal and plasmid molecular epidemiology of NDM transmission involving four institutions in Singapore.Thirty-three Enterobacteriaceae isolates (collection
Khong, Wei Xin, Marimuthu, Kalisvar, Teo, Jeanette, Ding, Yichen, Xia, Eryu, Lee, Jia Jun, Ong, Rick Twee-Hee, Venkatachalam, Indumathi, Cherng, Benjamin, Pada, Surinder Kaur, Choong, Weng Lam, Smitasin, Nares, Ooi, Say Tat, Deepak, Rama Narayana, Kurup, Asok, Fong, Raymond, Van La, My, Tan, Thean Yen, Koh, Tse Hsien, Lin, Raymond Tzer Pin, Tan, Eng Lee, Krishnan, Prabha Unny, Singh, Siddhar, Pitout, Johann D.D., Teo, Yik-Ying, Yang, Liang, Ng, Oon Tek   +26 more
openaire   +3 more sources

Adaptation of IncX3 Plasmid Encoding blaNDM-4 within A Broad Host Range

Journal of Microbiology and Infectious Diseases, 2021
Objectives: The current study was aimed to investigate the adaptability and stability of blaNDM-4 within a broad host range and transcriptional response.Methods: Six isolates of Escherichia coli, harboring blaNDM-4 were confirmed by PCR sequencing of the
Nargis Alom Choudhury, Deepjyoti Paul, Bhaskar Jyoti Das, Debadatta Dhar Chanda, Amitabha Bhattacharjee   +4 more
doaj   +1 more source