Results 1 to 10 of about 30,220 (240)

Rapidly spreading Enterobacterales with OXA-48-like carbapenemases [PDF]

Journal of Clinical Microbiology
Enterobacterales (mostly Klebsiella pneumoniae, Escherichia coli) with OXA-48-like carbapenemases (e.g., OXA-48, -181, -232, -244) are undermining the global efficiency of carbapenem therapy. In the Middle East, North Africa, and some European countries,
Gisele Peirano, Johann D. D. Pitout
doaj   +4 more sources

Emergence of OXA-48-like Carbapenemase-Producing Escherichia coli in Baranya County, Hungary [PDF]

Antibiotics
Background: Carbapenem-resistant Escherichia coli (CREC) producing OXA-48-like carbapenemase was first detected in Hungary in 2022. The aim of the present study was to characterize such strains isolated in 2022–2025 in Baranya County, Hungary.
Fatma A. Mohamed, Mohamed Al-Bulushi, Szilvia Melegh, Bálint Timmer, Réka Meszéna, Csongor Freytag, Levente Laczkó, László Miló, Péter Urbán, Renáta Bőkényné-Tóth, Attila Gyenesei, Gábor Kardos, Adrienn Nyul, Edit Urbán, Tibor Pál, Ágnes Sonnevend   +15 more
doaj   +2 more sources

Genetic characteristics of OXA-48-producing Enterobacterales from China

Journal of Global Antimicrobial Resistance, 2021
: Objectives: In China, OXA-48-producing Enterobacterales have been identified sporadically, causing small-scale regional outbreaks. This study investigated the molecular epidemiology, transmission and evolution of OXA-48-producing Enterobacterales and ...
Lifeng Wang, Ling Guo, Kun Ye, Jiyong Yang   +3 more
doaj   +3 more sources

Predominance of OXA-48 carbapenemase-producing Klebsiella pneumoniae strains in tertiary hospital in Sarajevo, Bosnia and Herzegovina [PDF]

Biomolecules & Biomedicine
Klebsiella pneumoniae, a member of the Enterobacteriaceae family, demonstrates an increasing trend of resistance to carbapenems and is a common cause of both hospital- and community-acquired infections.
Amela Dedeić Ljubović, Đana Granov, Edina Zahirović, Azra Čamdžić, Adis Muhić, Irma Salimović Bešić   +5 more
doaj   +2 more sources

OXA-48-like carbapenemases in Proteus mirabilis – novel genetic environments and a challenge for detection [PDF]

Emerging Microbes and Infections
OXA-48-like enzymes represent the most frequently detected carbapenemases in Enterobacterales in Western Europe, North Africa and the Middle East. In contrast to other species, the presence of OXA-48-like in Proteus mirabilis leads to an unusually ...
Janko Sattler, Janina Noster, Yvonne Stelzer, Martina Spille, Sina Schäfer, Kyriaki Xanthopoulou, Julian Sommer, Jonathan Jantsch, Silke Peter, Stephan Göttig, Sören G. Gatermann, Axel Hamprecht   +11 more
doaj   +2 more sources

OXA β-Lactamases [PDF]

Clinical Microbiology Reviews, 2014
The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Benjamin A Evans
exaly   +4 more sources

Multicenter evaluation of ceftazidime-avibactam use in carbapenem-resistant Klebsiella pneumoniae bloodstream infections in OXA-48 endemic regions [PDF]

Scientific Reports
Data in the literature on the use of ceftazidime-avibactam (CAZ-AVI) in carbapenem-resistant Klebsiella pneumoniae bloodstream infections (CRKP-BSIs) are limited especially in OXA-48 (Oxacillinase-48) predominant regions.
Ali Mert, Okan Derin, Halis Akalın, Rıdvan Dumlu, Sibel Gündeş, Rehile Zengin, Sesin Kocagöz, Yasemin Gündoğdu, İftihar Köksal, Demet Yalçın, Cemal Üstün, Mahir Kapmaz, Levent Görenek, Kadriye Karahangil, Füsun Can, Consortium, Önder Ergönül   +16 more
doaj   +2 more sources

Spread of the blaOXA-48/IncL Plasmid within and between Dogs in City Parks, France

Microbiology Spectrum, 2022
The blaOXA-48/IncL plasmid is increasingly reported in dogs, even in the absence of carbapenem use in animals. In this study, we witnessed the spread of this plasmid within and between dogs sharing the same relaxing area.
Marisa Haenni, Véronique Métayer, Agnese Lupo, Antoine Drapeau, Jean-Yves Madec   +4 more
doaj   +1 more source

Discovery of bla(OXA-199), a chromosome-based bla(OXA-48)-like variant, in Shewanella xiamenensis. [PDF]

PLoS ONE, 2012
INTRODUCTION: bla(OXA-48) is a globally emerging carbapenemase-encoding gene. The progenitor of bla(OXA-48) appears to be a Shewanella species. The presence of the bla(OXA-48)-like gene was investigated for two Shewanella xiamenensis strains.
Zhiyong Zong
doaj   +1 more source

Characterization of OXA-48-producing Klebsiella oxytoca isolates from a hospital outbreak in Tunisia

Journal of Global Antimicrobial Resistance, 2021
Objective: There is very limited information about OXA-48-producing Klebsiella oxytoca. The aim of this study was to describe the phenotypic and molecular characterization of OXA-48-producing K.
Julia Guzmán-Puche, Rim Jenayeh, María Pérez-Vázquez, Manuel-Causse, Ferjani Asma, Boukadida Jalel, Jesús Oteo-Iglesias, Luis Martínez-Martínez   +7 more
doaj   +1 more source