Rapidly spreading Enterobacterales with OXA-48-like carbapenemases [PDF]
Journal of Clinical MicrobiologyEnterobacterales (mostly Klebsiella pneumoniae, Escherichia coli) with OXA-48-like carbapenemases (e.g., OXA-48, -181, -232, -244) are undermining the global efficiency of carbapenem therapy. In the Middle East, North Africa, and some European countries,
Gisele Peirano, Johann D. D. Pitout
doaj +4 more sources
Discovery of bla(OXA-199), a chromosome-based bla(OXA-48)-like variant, in Shewanella xiamenensis. [PDF]
PLoS ONE, 2012 INTRODUCTION: bla(OXA-48) is a globally emerging carbapenemase-encoding gene. The progenitor of bla(OXA-48) appears to be a Shewanella species. The presence of the bla(OXA-48)-like gene was investigated for two Shewanella xiamenensis strains.
Zhiyong Zong
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Emergence of OXA-48-like Carbapenemase-Producing Escherichia coli in Baranya County, Hungary [PDF]
AntibioticsBackground: Carbapenem-resistant Escherichia coli (CREC) producing OXA-48-like carbapenemase was first detected in Hungary in 2022. The aim of the present study was to characterize such strains isolated in 2022–2025 in Baranya County, Hungary.
Fatma A. Mohamed +15 more
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Improved hydrolysis of piperacillin by OXA-48-like R214G variants, a selective advantage under piperacillin-tazobactam exposure [PDF]
Antimicrobial Agents and ChemotherapyOXA-48-like carbapenemases have rapidly disseminated worldwide, becoming the most common carbapenemase in many countries, with more than 60 variants reported.
Réva Nermont +5 more
doaj +2 more sources
Genetic characteristics of OXA-48-producing Enterobacterales from China
Journal of Global Antimicrobial Resistance, 2021 : Objectives: In China, OXA-48-producing Enterobacterales have been identified sporadically, causing small-scale regional outbreaks. This study investigated the molecular epidemiology, transmission and evolution of OXA-48-producing Enterobacterales and ...
Lifeng Wang +3 more
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One-Step Differential Detection of OXA-48-Like Variants Using High-Resolution Melting (HRM) Analysis [PDF]
Antibiotics, 2020 OXA-48-like carbapenemase gene remains a hidden threat, as different OXA-48 variants have varying presentations of susceptibility to antibiotics that might affect the treatment decisions.
Min Yi Lau +6 more
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Clinical outcomes of carbapenem therapy in OXA-48–producing Enterobacterales infections: a French multicentre cohort, systematic review, and meta-analysis [PDF]
Emerging Microbes and InfectionsOXA-48–producing Enterobacterales (OXA-48-PE) represent a growing global health threat. Most of OXA-48–PE remain categorized susceptible to carbapenems, which might encourage their use despite uncertain clinical efficacy.
Laurent Dortet +8 more
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Spread of the blaOXA-48/IncL Plasmid within and between Dogs in City Parks, France
Microbiology Spectrum, 2022 The blaOXA-48/IncL plasmid is increasingly reported in dogs, even in the absence of carbapenem use in animals. In this study, we witnessed the spread of this plasmid within and between dogs sharing the same relaxing area.
Marisa Haenni +4 more
doaj +1 more source
Characterization of OXA-48-producing Klebsiella oxytoca isolates from a hospital outbreak in Tunisia
Journal of Global Antimicrobial Resistance, 2021 Objective: There is very limited information about OXA-48-producing Klebsiella oxytoca. The aim of this study was to describe the phenotypic and molecular characterization of OXA-48-producing K.
Julia Guzmán-Puche +7 more
doaj +1 more source
Journal of Global Infectious Diseases, 2016 Carbapenemase producing Gram-negative pathogen is of great concern for physician. The challenging aspects are treatment option and infection control.
Yamuna Devi Bakthavatchalam +2 more
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