Results 11 to 20 of about 1,076,076 (217)

OXA-484, an OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamase From Escherichia coli

Frontiers in Microbiology, 2021
OXA-48-like carbapenemases are among the most frequent carbapenemases in Gram-negative Enterobacterales worldwide with the highest prevalence in the Middle East, North Africa and Europe.
Sara Riedel-Christ, Janko Sattler, Axel Hamprecht   +2 more
exaly   +4 more sources

OXA 48 Mediated Ceftazidime Avibactam Resistance Is Associated with Evolutionary Trade Offs [PDF]

mSphere, 2019
Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity.
Thomassen, A.M., Samuelsen, O., Fröhlich, Christopher, Frøhlich, Christopher, Sørum, Vidar, Fröhlich, C., Johnsen, P.J., Thomassen, Ane Molden, Johnsen, Pål Jarle, Leiros, H. K.S., Samuelsen, Ørjan, S rum, V.   +11 more
core   +5 more sources

Discovery of bla(OXA-199), a chromosome-based bla(OXA-48)-like variant, in Shewanella xiamenensis. [PDF]

PLoS ONE, 2012
INTRODUCTION: bla(OXA-48) is a globally emerging carbapenemase-encoding gene. The progenitor of bla(OXA-48) appears to be a Shewanella species. The presence of the bla(OXA-48)-like gene was investigated for two Shewanella xiamenensis strains.
Zhiyong Zong, Zong Zhiyong
core   +2 more sources

Genetic characteristics of OXA-48-producing Enterobacterales from China

Journal of Global Antimicrobial Resistance, 2021
In China, OXA-48-producing Enterobacterales have been identified sporadically, causing small-scale regional outbreaks. This study investigated the molecular epidemiology, transmission and evolution of OXA-48-producing Enterobacterales and pOXA48 from mainland China.We conducted a multicentre resistance monitoring project from 2013-2018.
Lifeng Wang, Ling Guo, Kun Ye, Jiyong Yang   +3 more
openaire   +4 more sources

Arising Prevalence of OXA-48 producer Escherichia coli and OXA-48 with NDM co-producer Klebsiella pneumoniae Strains [PDF]

Revista Romana de Medicina de Laborator, 2019
Abstract Background/aim : This prospective study aimed to determine the presence of the most common carbapenemase genes, blaOXA-48, blaKPC, blaIMP, blaVIM and blaNDM on carbapenem resistant clinical K.pneumoniae and E.coli isolates. Materials and methods :
Uskudar-Guclu Aylin, Guney Mustafa, Sig Ali Korhan, Kilic Selcuk, Baysallar Mehmet   +4 more
openaire   +2 more sources

Emergence of OXA-48-Producing Klebsiella pneumoniae in Taiwan

PLOS ONE, 2015
The isolation of OXA-48-producing Enterobacteriaceae has increased dramatically in Mediterranean countries in the past 10 years, and has recently emerged in Asia. Between January 2012 and May 2014, a total of 760 carbapenem non-susceptible Klebsiella pneumoniae (CnSKP) isolates were collected during a Taiwan national surveillance.
Ling Ma, Jann-Tay Wang, Tsu-Lan Wu, L Kristopher Siu, Yin-Ching Chuang, Jung-Chung Lin, Min-Chi Lu, Po-Liang Lu   +7 more
core   +6 more sources

Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France [PDF]

Clinical Microbiology and Infection, 2014
We characterized 53 OXA-48-producing Klebsiella pneumoniae (OXA-48-Kp) isolated between 2011 and 2013 in 21 French hospitals. All the isolates were genotyped using MLST and PFGE and the population structure of the species was determined by a nucleotide-based analysis of the entire K. pneumoniae MLST database.
Liapis, E., Pantel, A., Robert, J., Nicolas-Chanoine, M.-H., Cavalié, L., van Der Mee-Marquet, N., de Champs, C., Aissa, N., Eloy, C., Blanc, V., Guyeux, Christophe, Hocquet, D., Lavigne, J.-P., Bertrand, X., Renseigné, Non   +14 more
openaire   +4 more sources

One-step differential detection of OXA-48-like variants using high-resolution melting (HRM) analysis [PDF]

Antibiotics, 2020
OXA-48-like carbapenemase gene remains a hidden threat, as different OXA-48 variants have varying presentations of susceptibility to antibiotics that might affect the treatment decisions.
Sasheela Sri La Sri Ponnampalavanar, Teh, Cindy Shuan Ju, Lau, Min Yi, Kee, Boon Pin, Kek Heng Chua, Ponnampalavanar, Sasheela Sri La Sri, Chun Wie Chong, Chong, Chun Wie, Boon Pin Kee, Jabar, Kartini Abdul, Min Yi Lau, Cindy Shuan Ju Teh, Kartini Abdul Jabar, Chua, Kek Heng   +13 more
core   +3 more sources

Detection of OXA-48-Carbapenemase-Producing Enterobacteriaceae using ChromID OXA-48 in Critical Care Patients in Egypt

Journal of Pure and Applied Microbiology, 2017
Carbapenems are a class of beta-lactam antibiotics with broad spectrum of activity. They are often considered as a last resort in treatment of infections caused by multidrug resistant organisms. Carbapenemase-producing Enterobacteriaceae (CPE) have been reported worldwide.
Basma A. El Awady, Mera G. Anan, Hamida A. Gohar, Mohamed H. Saleh   +3 more
openaire   +3 more sources

Cefiderocol Comparative Resistance and Clinical Predictors in CRE-BSI: Data from an OXA-48-Endemic Region with Rising OXA-48/NDM Coproducers. [PDF]

Antibiotics (Basel)
Background/Objectives: Bloodstream infections (BSIs) caused by carbapenem-resistant Enterobacterales (CREs) are a growing public health threat due to limited therapeutic options and high mortality. In Turkey, oxacillinase-48 (OXA-48) producers predominate, while OXA-48/New Delhi metallo-β-lactamase (NDM) co-producers are increasingly detected. Although
Dumlu R, Mert A.
europepmc   +4 more sources