Results 41 to 50 of about 1,473,629 (228)

Klebsiella Species and Enterobacter cloacae Isolates Harboring blaOXA-181 and blaOXA-48: Resistome, Fitness Cost, and Plasmid Stability

Microbiology Spectrum, 2022
IncX3 and IncL plasmids have been named as catalysts advancing dissemination of blaOXA-181 and blaOXA-48 genes. However, their impact on the performance of host cells is vastly understudied. Genetic characteristics of blaOXA-48- and blaOXA-181-containing
Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito   +11 more
doaj   +1 more source

Prospective evaluation of the OXA-48K-SeT assay, an immunochromatographic test for the rapid detection of OXA-48-type carbapenemases [PDF]

Journal of Antimicrobial Chemotherapy, 2016
There is an urgent need for accurate and fast diagnostic tests to identify MDR bacteria. Here, we evaluated an immunochromatographic assay (the OXA-48 K-SeT assay) to detect OXA-48-like carbapenemase-producing Enterobacteriaceae from culture colonies.One hundred and sixty-one collection isolates with characterized β-lactamase content and 185 non ...
Laurent, Dortet, Agnès, Jousset, Vincent, Sainte-Rose, Gaëlle, Cuzon, Thierry, Naas   +4 more
openaire   +2 more sources

Evaluation of an Immunochromatographic Lateral Flow Assay (OXA-48 K -SeT) for Rapid Detection of OXA-48-Like Carbapenemases in Enterobacteriaceae [PDF]

Journal of Clinical Microbiology, 2016
ABSTRACT We evaluated an immunochromatographic lateral flow assay to detect OXA-48-like carbapenemases (OXA-48 K -SeT) in Enterobacteriaceae ( n = 82). One hundred percent sensitivity and specificity were observed using bacteria recovered from both solid ...
Wareham, DW, Shah, R, Betts, JW, Phee, LM, Momin, MHFA   +4 more
openaire   +4 more sources

OXA-181 Beta Lactamase is not a Major Mediator of Carbapenem Resistance in Enterobacteriaceae [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Detection of carbapenem hydrolyzing class D beta lactamase OXA-181, (a variant of OXA-48) in Enterobacteriaceae, is important, to institute appropriate therapy and to initiate preventive measures.
M. Shanthi, Uma Sekar, Arunagiri K., Hemant Goverdhandas Bramhne   +3 more
doaj   +1 more source

Association Between Types of Carbapenemase and Clinical Outcomes of Infection Due to Carbapenem Resistance Enterobacterales

Infection and Drug Resistance, 2022
Korawan Pudpong,1,2 Sutthiporn Pattharachayakul,3 Wichai Santimaleeworagun,4,5 Ozioma F Nwabor,6 Varaporn Laohaprertthisan,7 Thanaporn Hortiwakul,6 Boonsri Charernmak,6 Sarunyou Chusri6 1Department of Pharmacy, College of Pharmacotherapy Thailand ...
Pudpong K, Pattharachayakul S, Santimaleeworagun W, Nwabor NF, Laohaprertthisan V, Hortiwakul T, Charernmak B, Chusri S   +7 more
doaj  

Detection of OXA-181 Carbapenemase in Shigella flexneri

Emerging Infectious Diseases
We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria in an immunocompromised patient. The emergence of OXA-181 in Shigella spp.
Ghulam Dhabaan, Hassan Jamal, Danielle Ouellette, Sarah Alexander, Karen Arane, Aaron Campigotto, Manal Tadros, Pierre-Philippe Piché-Renaud   +7 more
doaj   +1 more source

Detection of rare carbapenemases in Enterobacterales—comparison of two colorimetric and three CIM-based carbapenemase assays

Microbiology Spectrum
Rapid and reliable detection of carbapenemase-producing Enterobacterales (CPE) is crucial for prompt treatment and infection control. Most assays target the primary four enzymes (KPC, OXA-48-like, VIM, and NDM), often missing less common variants (e.g ...
Lukas Schaffarczyk, Janina Noster, Yvonne Stelzer, Janko Sattler, Sören Gatermann, Axel Hamprecht   +5 more
doaj   +1 more source

Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK [PDF]

Journal of Antimicrobial Chemotherapy, 2012
To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like carbapenemases and to compare their resistance plasmids.Twenty-six enterobacteria producing OXA-48-like enzymes were studied. These were from 22 diverse hospitals in the UK.
Dimou, Vassiliki, Dhanji, Hiran, Pike, Rachel, Livermore, David M., Woodford, Neil   +4 more
openaire   +3 more sources

OXA-48 model.

, 2015
(a) Model of population flow. (b) Within-host model in the hospital. (c) Within-host model in the community with a high risk of readmission. (d) Within-host model in the community with a low risk of readmission.
Tjaco J. M. Ossewaarde (815852), Anneke van der Zee (815853), Annet Troelstra (112779), Mirjam J. D. Dautzenberg (815851), Manon R. Haverkate (815850), Marc J. M. Bonten (109524), Jan G. den Hollander (815854), Martin C. J. Bootsma (380313)   +7 more
core   +1 more source

Emergence and Spread of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae [PDF]

, 2015
Since 2001, ten more OXA-48 variants have been identified. Shewanella spp. has been thought to be the original host for OXA-48-like enzymes. These enzymes strongly hydrolyze penicillins and weakly hydrolyze carbapenems, with very weak activity against ...
이경원, 정석훈
core   +1 more source