Results 51 to 60 of about 1,076,076 (217)

Detection of OXA-181 Carbapenemase in Shigella flexneri

Emerging Infectious Diseases
We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria in an immunocompromised patient. The emergence of OXA-181 in Shigella spp.
Ghulam Dhabaan, Hassan Jamal, Danielle Ouellette, Sarah Alexander, Karen Arane, Aaron Campigotto, Manal Tadros, Pierre-Philippe Piché-Renaud   +7 more
doaj   +1 more source

OXA-48-like carbapenemases in Proteus mirabilis - novel genetic environments and a challenge for detection. [PDF]

Emerg Microbes Infect
OXA-48-like enzymes represent the most frequently detected carbapenemases in Enterobacterales in Western Europe, North Africa and the Middle East. In contrast to other species, the presence of OXA-48-like in Proteus mirabilis leads to an unusually ...
Sattler J, Noster J, Stelzer Y, Spille M, Schäfer S, Xanthopoulou K, Sommer J, Jantsch J, Peter S, Göttig S, Gatermann SG, Hamprecht A.   +11 more
europepmc   +2 more sources

Emergence and Spread of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae [PDF]

, 2015
Since 2001, ten more OXA-48 variants have been identified. Shewanella spp. has been thought to be the original host for OXA-48-like enzymes. These enzymes strongly hydrolyze penicillins and weakly hydrolyze carbapenems, with very weak activity against ...
이경원, 정석훈
core   +1 more source

OXA-48 model.

, 2015
(a) Model of population flow. (b) Within-host model in the hospital. (c) Within-host model in the community with a high risk of readmission. (d) Within-host model in the community with a low risk of readmission.
Tjaco J. M. Ossewaarde (815852), Anneke van der Zee (815853), Annet Troelstra (112779), Mirjam J. D. Dautzenberg (815851), Manon R. Haverkate (815850), Marc J. M. Bonten (109524), Jan G. den Hollander (815854), Martin C. J. Bootsma (380313)   +7 more
core   +1 more source

Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK [PDF]

Journal of Antimicrobial Chemotherapy, 2012
To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like carbapenemases and to compare their resistance plasmids.Twenty-six enterobacteria producing OXA-48-like enzymes were studied. These were from 22 diverse hospitals in the UK.
Dimou, Vassiliki, Dhanji, Hiran, Pike, Rachel, Livermore, David M., Woodford, Neil   +4 more
openaire   +3 more sources

Effects of single and multiple OXA-48 mutants on enzyme activity, stability, and structure-activity relationship. Evolutionary consequences of antibiotic resistance development caused by OXA-48 [PDF]

, 2022
Antimicrobial resistance, primarily caused by the overuse of antimicrobials such as antibiotics, is becoming an increasing concern to public health.
Martinsen, Nina Nevjar
core  

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Detection of rare carbapenemases in Enterobacterales—comparison of two colorimetric and three CIM-based carbapenemase assays

Microbiology Spectrum
Rapid and reliable detection of carbapenemase-producing Enterobacterales (CPE) is crucial for prompt treatment and infection control. Most assays target the primary four enzymes (KPC, OXA-48-like, VIM, and NDM), often missing less common variants (e.g ...
Lukas Schaffarczyk, Janina Noster, Yvonne Stelzer, Janko Sattler, Sören Gatermann, Axel Hamprecht   +5 more
doaj   +1 more source

Unveiling the Emergence and Genetic Diversity of OXA-48-like Carbapenemase Variants in Shewanella xiamenensis

Microorganisms, 2023
An increase in the carbapenem-hydrolyzing capacity of class D β-lactamase has been observed in strains of multiple species, posing a significant challenge to the control of antibiotic resistance.
Xueqi Jiang, Beibei Miao, Xiaofei Zhao, Xuemei Bai, Min Yuan, Xia Chen, Xinyi Gong, Zeliang Liu, Jie Li, Shuang Meng, Xiao Han, Juan Li   +11 more
doaj   +1 more source

Dynamics and molecular features of OXA-48-like-producing Klebsiella pneumoniae lineages in a Tunisian hospital

Journal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to elucidate the molecular features of genes, plasmids and clones of OXA-48-like producingKlebsiella pneumoniae isolates recovered in Sahloul Hospital (Sousse, Tunisia) in the period 2012–2014.
Aziza Messaoudi, Marisa Haenni, Olfa Bouallègue, Estelle Saras, Pierre Chatre, Cherifa Chaouch, Noureddine Boujâafar, Wejdene Mansour, Jean-Yves Madec   +8 more
doaj   +1 more source