Results 1 to 10 of about 17,864 (222)
Carbapenemases as factors of Resistance to Antibacterial Drugs [PDF]
Acta Biomedica Scientifica, 2021 Antibiotic drugs are used to treat and prevent bacterial infections around the world. The emergence and spread of bacterial resistance to carbapenems is currently a real threat that determines the need for its timely detection and suppression ...
A. V. Nevezhina
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Expression analysis of drug-resistant gene (blaOXA-51) in carbapenemases producing Acinetobacter baumannii treated with imipenem/sulbactam combination [PDF]
Brazilian Journal of Pharmaceutical Sciences, 2021 Drug-resistant Acinetobacter baumannii is a frightening reality. The aim of this study is to examine the expression profiles of blaOXA-51 gene in carbapenemases producing A. baumannii treated with imipenem/sulbactam combination.
Saber Noshadi, Alireza Khodavandi
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The in vitro activity of aztreonam-avibactam and cefiderocol against globally collected clinical metallo-β-lactamase- and/or serine-carbapenemase-positive Enterobacterales isolates and the utility of commonly used in vitro diagnostic kits [PDF]
Microbiology SpectrumThe NG-test CARBA 5 and Xpert Carba-R IVD kits were tested against 269 clinical Enterobacterales isolates selected for their previously determined carbapenemase content from the ATLAS Global Surveillance program, primarily from 2020 to 2022 ...
Mark Estabrook +5 more
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Detection of OXA-23 and OXA-58 in Proteus mirabilis by immunochromatographic assays [PDF]
Microbiology SpectrumProteus mirabilis is increasingly recognized as a carrier of carbapenemases, which are particularly difficult to identify, since most isolates have low carbapenem MICs. Additionally, most phenotypic tests (e.g.
Janina Noster-Schrader +7 more
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Carriage of K. pneumoniae and molecular structure of produced carbapenemases in infants with congenital heart defects [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Objective. To evaluate frequency of pharyngeal and rectal mucosa colonization by K. pneumoniae strains in infants with congenital heart defects at the stage of cardiosurgical hospital admission, as well as dynamic analysis of production frequency and ...
Popov D.A. +2 more
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To Be or Not to Be an OXA-48 Carbapenemase [PDF]
Microorganisms, 2022 Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems and penicillins with very weak or almost no activity against expanded-spectrum cephalosporins, some ...
Laura Dabos +5 more
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Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa
African Journal of Laboratory Medicine, 2023 This study evaluated the performance of the Xpert Carba-R assay for detecting the five common carbapenemases in carbapenemase-producing organisms in Johannesburg, South Africa between April 2021 and September 2021.
Sanelisiwe T. Duze +5 more
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Frontiers in Medicine, 2021 Gram-negative bacteria, especially Enterobacterales, have emerged as major players in antimicrobial resistance worldwide. Resistance may affect all major classes of anti-gram-negative agents, becoming multidrug resistant or even pan-drug resistant ...
Rémy A. Bonnin +20 more
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Антибиотики и Химиотерапия, 2022 The rapid spread of gram-negative bacteria resistance to carbapenems due to the production of carbapenemases requires new treatment options. The activity of carbapenem antibiotic biapenem, recently registered in Russia, against producers of various ...
V. A. Ageevets +9 more
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Journal of Antimicrobial Chemotherapy, 2007 Carbapenems, such as imipenem and meropenem, are most often used to treat infections caused by enterobacteria that produce extended-spectrum beta-lactamases, and the emergence of enzymes capable of inactivating carbapenems would therefore limit the options for treatment.
Walther-Rasmussen, J., Høiby, N.
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