Results 21 to 30 of about 24,917 (198)
Carbapenemases in Enterobacteriaceae: Detection and Antimicrobial Therapy
Frontiers in Microbiology, 2019 Carbapenem-resistant Enterobacteriaceae (CRE) have spread rapidly around the world in the past few years, posing great challenges to human health. The plasmid-mediated horizontal transmission of carbapenem-resistance genes is the main cause of the surge ...
Hong Du
exaly +2 more sources
Antibiotics, 2020 The Enterobacteriales order consists of seven families including Enterobacteriaceae, Erwiniaceae, Pectobacteriaceae, Yersiniaceae, Hafniaceae, Morganellaceae, and Budviciaceae and 60 genera encompassing over 250 species.
Gurleen Taggar +3 more
doaj +2 more sources
Epidemiology and clinical significance of carbapenemases in Australia: a narrative review
Internal Medicine JournalCarbapenemase‐producing gram‐negative bacteria (CP‐GNB) infections threaten public health with high mortality, morbidity and treatment costs. Although frequencies remain low in Australia (total number of CP‐GNB infections reported was 907 in 2022 ...
David Paterson
exaly +2 more sources
AZETIDINIMINES AS CARBAPENEMASES INHIBITORS
, 2017 The present application relates to novel azetidinimine of formula (I). Wherein R1-R6 are as defined in claim 1. The azetidinimine of the invention are useful as antibiotics and as inhibitors of a carbapenemases. The present invention thus further relates
DODD ROBERT +4 more
core +6 more sources
Update on the epidemiology of carbapenemases in Latin America and the Caribbean
Expert Review of Anti-Infective Therapy, 2020 Introduction Carbapenemases are β-lactamases able to hydrolyze a wide range of β-lactam antibiotics, including carbapenems. Carbapenemase production in Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter spp., with and without the co-expression ...
J. C. García-Betancur +12 more
semanticscholar +3 more sources
Antibiotics, 2019 During a six-month period (October 2017–March 2018), the prevalence and susceptibility of important pathogenic bacteria isolated from 12 hospital raw sewage samples in North Western Greece was investigated.
Papadopoulou C +2 more
exaly +2 more sources
Activity of imipenem/relebactam against Pseudomonas aeruginosa producing ESBLs and carbapenemases. [PDF]
Journal of Antimicrobial Chemotherapy, 2020 BACKGROUND ESBL- and carbapenemase-producing Pseudomonas aeruginosa are prevalent in, for example, the Middle East, Eastern Europe and Latin America, though rarer elsewhere. Because P.
S. Mushtaq +4 more
semanticscholar +2 more sources
Carbapenemases: the Versatile β-Lactamases [PDF]
Clinical Microbiology Reviews, 2007 SUMMARYCarbapenemases are β-lactamases with versatile hydrolytic capacities. They have the ability to hydrolyze penicillins, cephalosporins, monobactams, and carbapenems. Bacteria producing these β-lactamases may cause serious infections in which the carbapenemase activity renders many β-lactams ineffective.
A. Queenan, K. Bush
semanticscholar +3 more sources
Carriage of K. pneumoniae and molecular structure of produced carbapenemases in infants with congenital heart defects [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 Objective. To evaluate frequency of pharyngeal and rectal mucosa colonization by K. pneumoniae strains in infants with congenital heart defects at the stage of cardiosurgical hospital admission, as well as dynamic analysis of production frequency and ...
Popov D.A. +2 more
doaj +1 more source
To Be or Not to Be an OXA-48 Carbapenemase [PDF]
Microorganisms, 2022 Since the first description of OXA-48, more than forty variants have been recovered from Enterobacterales isolates. Whereas some OXA-48-related enzymes have been reported as conferring similar resistance patterns, namely, the hydrolysis of carbapenems and penicillins with very weak or almost no activity against expanded-spectrum cephalosporins, some ...
Laura Dabos +5 more
openaire +3 more sources