Results 31 to 40 of about 24,596 (232)

Structural and Functional Aspects of Class A Carbapenemases. [PDF]

, 2016
The fight against infectious diseases is probably one of the greatest public health challenges faced by our society, especially with the emergence of carbapenem-resistant gram-negatives that are in some cases pan-drug resistant.
Dortet, L, Iorga, BI, Naas, T
core   +3 more sources

The Immaculate Carbapenemase Study [PDF]

Journal of Clinical Microbiology, 2017
ABSTRACT Carbapenemase-producing organisms, or CPOs, are Gram-negative pathogens that produce a transmissible carbapenemase and are typically resistant to most (sometimes all) antibiotics. We now face a global CPO pandemic of high mortality. In this issue of the Journal of Clinical Microbiology , Karlowsky
openaire   +2 more sources

Difference in Susceptibility Between Carbapenemase- and Non–Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae [PDF]

Antimicrobial Stewardship & Healthcare Epidemiology, 2021
Background: Carbapenem-resistant Enterobacteriaceae (CRE) remain among the most urgent infectious threats according to the CDC Threats Reports. Although focus has often been placed on carbapenemase-producing phenotypes, there is increasing interest in distinguishing the optimal treatment and outcomes of carbapenemase-producing (CP) and non ...
Clark, Justin, Burgess, David
openaire   +1 more source

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae [PDF]

, 2018
Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which
Cebrero Cangueiro, Tania, Cordero Matia, María Elisa, Labrador Herrera, Gema, Smani, Younes, Álvarez Marín, Rocío   +4 more
core   +1 more source

Carbapenemases

, 2019
Carbapenems are usually regarded as the last treatment option for serious infections caused by Gram-negative and Gram-positive microorganisms. Although they are stable to hydrolysis by most β- lactamases, their usage as the last resort antbiotics was seriously compromised by the appearance of carbapenem-hydrolyzing enzymes called carbapenemases.
Bedenić, Branka, Sardelić, Sanda
openaire   +2 more sources

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]

, 2016
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
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core   +4 more sources

Fecal Carriage and Epidemiology of Extended-Spectrum Beta-Lactamase/Carbapenemases Producing Enterobacterales Isolates in Bulgarian Hospitals

Antibiotics, 2021
The gastrointestinal tract is an important reservoir of extended spectrum beta-lactamase (ESBL)/carbapenemase-producing Enterobacterales isolates. This study included patients from two Bulgarian hospitals.
Rumyana Markovska, Petya Stankova, Temenuga Stoeva, Dobrinka Ivanova, Daniela Pencheva, Radka Kaneva, Lyudmila Boyanova   +6 more
doaj   +1 more source

Carbapenemase-Producing Bacteria Isolated from ICU Patients of a Peruvian Government Hospital during the COVID-19 Pandemic: A Descriptive Analysis

Medicina, 2023
Background and Objectives: In Peru, the presence of antimicrobial-resistant bacteria is a constant concern in hospitals and has likely increased in frequency during the pandemic.
David García-Cedrón, Magaly De La Cruz Noriega, Luis Cabanillas-Chirinos, Nélida Milly Otiniano, Walter Rojas-Villacorta, Waldo Salvatierra-Espinola, Karen Diaz Del Aguila, Manuela Luján-Velásquez   +7 more
doaj   +1 more source

Detection and Characterization of Carbapenemase-Producing Escherichia coli and Klebsiella pneumoniae from Hospital Effluents of Ouagadougou, Burkina Faso

Antibiotics, 2023
Hospital wastewater is a recognized reservoir for resistant Gram-negative bacteria. This study aimed to screen for carbapenemase-producing Escherichia coli and Klebsiella pneumoniae and their resistance determinants in two hospital effluents of ...
Alix Bénédicte Kagambèga, René Dembélé, Léa Bientz, Fatima M’Zali, Laure Mayonnove, Alassane Halawen Mohamed, Hiliassa Coulibaly, Nicolas Barro, Véronique Dubois   +8 more
doaj   +1 more source

Comparison of Molecular and Phenotypic Methods for the Detection and Characterization of Carbapenem Resistant Enterobacteriaceae [PDF]

, 2016
In recent years, there has been a rapid dissemination of carbapenem resistant Enterobacteriaceae (CRE). This study aimed to compare phenotypic and molecular methods for detection and characterization of CRE isolates at a large tertiary care hospital in ...
Absar, Muhammad M., Abukhalid, Norah, Garaween, Ghada A., Senok, Abiola C., Somily, Ali M.   +4 more
core   +1 more source