Results 1 to 10 of about 827,661 (196)

Controversies about Extended-Spectrum and AmpC Beta-Lactamases

Emerging Infectious Diseases, 2001
Many clinical laboratories have problems detecting extended-spectrum beta-lactamases (ESBLs) and plasmid-mediated AmpC beta-lactamases. Confusion exists about the importance of these resistance mechanisms, optimal test methods, and appropriate reporting ...
Kenneth S. Thomson
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Screening of Epidemiologically Significant Mechanisms of Antibiotics to β-Lactams in Enterobacteriaceae - Pathogens of Zoonoses

Journal of Pure and Applied Microbiology, 2021
Among the acquired mechanisms of resistance to antibiotics of microorganisms, the production of beta-lactamases, enzymes that inactivate penicillins, cephalosporins, carbapenems, and monobactams, is widespread.
T.O. Garkavenko, O.I. Gorbatyuk, S.M. Dybkova, T.G. Kozytska, V.O. Andriiashchuk, M.D. Kukhtyn, Y.V. Horiuk   +6 more
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Potential involvement of beta-lactamase homologous proteins in resistance to beta-lactam antibiotics in gram-negative bacteria of the ESKAPEE group

BMC Genomics
Background Enzymatic degradation mediated by beta-lactamases constitutes one of the primary mechanisms of resistance to beta-lactam antibiotics in gram-negative bacteria.
Joyce de Souza, Alexandre Zanatta Vieira, Hellen Geremias dos Santos, Helisson Faoro   +3 more
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Susceptibility of strict and facultative anaerobes Isolated from endodontic infections to metronidazole and beta-lactams

Journal of Applied Oral Science, 2007
Endodontic infections are mixed aerobic-anaerobic infections and several microbial groups associated to these pathologies are also involved in orofacial infections. The goal of this study was to evaluate the susceptibility of microorganisms isolated from
Elerson Gaetti-Jardim Júnior, Luís Fernando Landucci, Samira Âmbar Lins, Evanice Menezes Marçal Vieira, Sérgio Ricardo de Oliveira   +4 more
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Design, Molecular Docking, Synthesis of Aromatic Amino Acids Linked to Cephalexin.

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022
Infections caused by bacteria have a significant impact on public health. Chemical synthesis of new derivatives of cephalexin inked to amino acid (tryptophan or histidine) through an amide bond at the acyl side chain is achieved.
Yasir F. Muhsin, Shakir M. Alwan, Ayad Kareem Khan   +2 more
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A study on detection of extended-spectrum beta-lactamases (ESBLs) and comparison of various phenotypic methods of AmpC detection in Pseudomonas aeruginosa from various clinical isolates in a tertiary care teaching hospital

Muller Journal of Medical Sciences and Research, 2016
Introduction: Pseudomonas aeruginosa is one of the major etiological agents of nosocomial infection. They are difficult to treat as the majority of them exhibit varying degrees of innate resistance.
Subbalakshmi Easwaran, Ranjani Chittur Yerat, Rajendran Ramaswamy   +2 more
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Analysis of Class 1 Integrons and Antibiotic Resistance Genes in Pseudomonas aeruginosa Strains from Benin City, Nigeria

Journal of Applied Sciences and Environmental Management, 2020
The presence of integrons and antibiotic resistance genes in the genome of Pseudomonas aeruginosa pose a serious problem in the treatment and control of infections caused by this pathogen in hospitals.
B.O. Isichei-Ukah, O.I. Enabulele
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Prevalence of extended-spectrum beta-lactamases, AmpC beta-lactamase, and metallo-beta-lactamase producing Pseudomonas aeruginosa and Acinetobacter baumannii in an intensive care unit in a tertiary care hospital

Journal of the Scientific Society, 2013
Background: Resistance to broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamases (ESBL), AmpC beta-lactamase, and metallo-beta-lactamase (MBL) enzymes, is an increasing problem worldwide. Aim of the study: This study was undertaken to
Varun Goel, Sumati A Hogade, S G Karadesai   +2 more
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Beta-lactamase resistance genes in Enterobacteriaceae from Nigeria

African Journal of Laboratory Medicine, 2022
Background: Beta-lactamase genes are one of the most important groups of antimicrobial resistance genes in human and animal health. Therefore, continuous surveillance of this group of resistance genes is needed for a better understanding of the local ...
Babafela B. Awosile, Michael Agbaje, Oluwawemimo Adebowale, Olugbenga Kehinde, Ezekiel Omoshaba   +4 more
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Antibacterial potential of neem (Azadirachta indica) against uropathogens producing beta-lactamase enzymes: A clue to future antibacterial agent?

Biomedical and Biotechnology Research Journal, 2020
Background: Emergence of drug resistance in Gram-negative bacilli due to production of extended-spectrum beta-lactamases (ESBL), metallo-beta-lactamases (MBL), and AmpC beta-lactamase is very common nowadays; therefore, we are left with less choice for ...
Sameer Singh Faujdar, Dakshina Bisht, Amisha Sharma   +2 more
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