Results 1 to 10 of about 798,093 (282)
Pharmaceuticals, 2021 Antibiotic resistance is a major health problem worldwide, causing more deaths than diabetes and cancer. The dissemination of vertical and horizontal antibiotic resistance genes has been conducted for a selection of pan-resistant bacteria.
Rosalino Vázquez-López +8 more
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Antibiotics, 2022 Aim: The aim of the study was to evaluate the in vitro activity of N-acetylcysteine (NAC), alone or in combination with beta-lactams, against carbapenem-resistant Klebsiella pneumoniae (CR-Kp) and Acinetobacter baumannii (CR-Ab).
Massimiliano De Angelis +9 more
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Zeitschrift für Naturforschung B, 1969 Since the discovery 11 of the activating effect of the N- (p-Nitro-phenyl)-group on the methine hydrogen of halogenacetamino esters, it has been found that the p-Acetyl-phenyl and m-Nitro-phenyl groups exert a similar effect. It has been shown that the delocalisation of the N-non-bonded electrons across the orbitals of the N-Aryl substituent is the ...
B G, Chatterjee, R F, Abdulla
openaire +2 more sources
Allergology International, 2011 Background: The leukocyte migration test (LMT) is effective in identifying the causative drug in drug allergies. Both leukocyte migration activating activity (LMAA) and leukocyte migration inhibitory activity (LMIA) are involved in the development of ...
Manabu Abe +4 more
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Oral beta-lactam step down in bacteremic E. coli urinary tract infections
BMC Infectious Diseases, 2020 Background Literature is scarce regarding oral step down to beta-lactams in bacteremic urinary tract infections. Oral fluoroquinolones are an accepted and common step down for bacteremic urinary tract infections; however, their use is associated with ...
Stephan Saad +3 more
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Frontiers in Cellular and Infection Microbiology, 2023 The lack of effective therapeutics against emerging multi-drug resistant strains of Mycobacterium tuberculosis (Mtb) prompts the identification of novel anti-tuberculosis targets.
Cátia Silveiro +10 more
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β-Lactam Allergy and Cross-Reactivity: A Clinician’s Guide to Selecting an Alternative Antibiotic
Journal of Asthma and Allergy, 2021 Cristiano Caruso,1 Rocco Luigi Valluzzi,2 Stefania Colantuono,1 Francesco Gaeta,1 Antonino Romano3,4 1Allergy Unit, Columbus Hospital, Fondazione Policlinico A.
Caruso C +4 more
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Design, synthesis, and evaluation the anti-β-lactamase activity of new sulphathiazole-derived monobactam compounds [PDF]
المجلة العراقية للصيدلة, 2020 Objectives: β-Lactams are the most successful antibiotics for the management of infectious diseases. Unfortunately, the bacterial production of β-lactamase that hydrolyzes the β-lactam ring can inactivate these drugs.
Ahmed Mahmood +2 more
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Antibiotics, 2021 Selective pressure of beta-lactams is thought to be responsible for mutation selection in methicillin-susceptible Staphylococcus aureus (MSSA). We used next-generation sequencing to compare the genomes of beta-lactamase-positive (SA0707) and -negative ...
Vladimir Gostev +6 more
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Identification of drivers of mycobacterial resistance to peptidoglycan synthesis inhibitors
Frontiers in Microbiology, 2022 Beta-lactams have been excluded from tuberculosis therapy due to the intrinsic resistance of Mycobacterium tuberculosis (Mtb) to this antibiotic class, usually attributed to a potent beta-lactamase, BlaC, and to an unusually complex cell wall.
Francisco Olivença +8 more
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