Results 31 to 40 of about 798,093 (282)

Docking Study for New 7-Aminocephalosporinic Acid Derivatives as Potential Inhibitors for β-Lactamases [PDF]

المجلة العراقية للصيدلة, 2023
Background: Antibiotics with β-Lactam rings (β-Lactams), since they were discovered, have enhanced the typical treatment for bacterial infections.
Ahmed A. Saleh, Ahmed A. J. Mahmood
doaj   +1 more source

The Subcutaneous Administration of Beta-Lactams: A Case Report and Literary Review—To Do Small Things in a Great Way [PDF]

Infectious Disease Reports
Chiara Moreal, Rita Murri, Carlo Tascini   +2 more
exaly   +2 more sources

Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines [PDF]

, 2014
This work is supported by a Royal Society for a University Research Fellowship and the EPSRC and GSK (Case Award) as well as by the European Research Council under the European Unionʼs Seventh Framework Programme (FP7/2007-2013) (ERC Grant Agreement No ...
Prevet, Hugues, Shapland, Peter, Smith, Andrew D., Douglas, James, Smith, Siobhan R., Slawin, Alexandra M. Z.   +5 more
core   +1 more source

Barriers and facilitators for therapeutic drug monitoring of beta-lactams and ciprofloxacin in the ICU: a nationwide cross-sectional study

BMC Infectious Diseases, 2022
Background Recent studies demonstrated that failure of achieving pharmacodynamic targets of commonly used antibiotics is common in critically ill patients.
Tim M. J. Ewoldt, Alan Abdulla, Puck van den Broek, Nicole Hunfeld, Soma Bahmany, Anouk E. Muller, Diederik Gommers, Suzanne Polinder, Henrik Endeman, Inge Spronk, Birgit C. P. Koch   +10 more
doaj   +1 more source

Efflux pump, the masked side of beta-lactam resistance in Klebsiella pneumoniae clinical isolates. [PDF]

PLoS ONE, 2009
BACKGROUND: Beta-lactamase production and porin decrease are the well-recognized mechanisms of acquired beta-lactam resistance in Klebsiella pneumoniae isolates. However, such mechanisms proved to be absent in K.
Jean-Marie Pages, Jean-Philippe Lavigne, Véronique Leflon-Guibout, Estelle Marcon, Frédéric Bert, Latifa Noussair, Marie-Hélène Nicolas-Chanoine   +6 more
doaj   +1 more source

Occurrence of TEM and SHV among extended-spectrum-beta lactamase producers of some Enterobacteriaceae members

Zagazig Journal of Pharmaceutical Sciences, 2016
This study aimed for the molecular detection of TEM and SHV genes in Extended-Spectrum beta-lactamases (ESBLs) clinical isolates of Enterobacteriace (Eshericichia coli, Klebsiella pneumoniae and Proteus spp.).
Ashraf Kadry , Eman El Masry , Dalia Serry   +2 more
doaj   +1 more source

Deciphering unexploited features of drug-repurposing beta-lactams against tuberculosis : from genomic patterns of Mycobacterium tuberculosis susceptibility to synergistic combinations

, 2023
Tuberculosis (TB) still figures as one of the leading death causes by a single infectious agent worldwide. The natural capacity of Mycobacterium tuberculosis (Mtb) to evade and subvert host immune responses, coupled with the increasing threat of drug ...
Olivença, Francisco
core  

Evaluation of Risk Factors for Carbapenem-Resistant Klebsiella Pneumoniae Bacteremia

Southern Clinics of Istanbul Eurasia, 2020
INTRODUCTION[|]In recent years, carbapenem-resistant Klebsiella pneumoniae infections have become an important health problem in our country and all over the world.
Pınar Kıran, Serap Gencer, Ayşe Batırel   +2 more
doaj   +1 more source

Synthesis of type II beta-turn surrogate dipeptides based on syn-alfa-amino-alfa, beta-dialkyl-beta-lactams [PDF]

, 2004
The achiral bis(trimethylsilyl)methyl group acts as an efficient stereochemical determinant of the α-alkylation reaction in β-branched α-phenyloxazolidinyl- or α-diphenyloxazolidinyl-β-lactams and provides the first stereocontrolled access to syn-α-amino-
Palomo, Claudio, Fratila, Raluca M., Cuerdo, Lourdes, Ganboa, Iñaki, Jimenez, Azucena, Linden, Anthony, Micle, Andreea, Loinaz, Iraida, Benito, Ana M., Aizpurua, Jesús M., Miranda, José Ignacio, Pytlewska, Kinga R.   +11 more
core   +1 more source

Profile of Enterobacteria Resistant to Beta-Lactams

Antibiotics, 2020
A serious emerging problem worldwide is increased antimicrobial resistance. Acquisition of coding genes for evasion methods of antimicrobial drug mechanisms characterizes acquired resistance. This phenomenon has been observed in Enterobacteriaceae family.
Andressa Liberal Santos, Adailton Pereira dos Santos, Célia Regina Malveste Ito, Pedro Henrique Pereira de Queiroz, Juliana Afonso de Almeida, Marcos Antonio Batista de Carvalho Júnior, Camila Zanatta de Oliveira, Melissa Ameloti G. Avelino, Isabela Jubé Wastowski, Giselle Pinheiro Lima Aires Gomes, Adenícia Custódia Silva e Souza, Lara Stefânia Netto de Oliveira Leão Vasconcelos, Mônica de Oliveira Santos, Carla Afonso da Silva, Lilian Carla Carneiro   +14 more
doaj   +1 more source