β-Lactam Allergy and Cross-Reactivity: A Clinician’s Guide to Selecting an Alternative Antibiotic
Cristiano Caruso,1 Rocco Luigi Valluzzi,2 Stefania Colantuono,1 Francesco Gaeta,1 Antonino Romano3,4 1Allergy Unit, Columbus Hospital, Fondazione Policlinico A.
Caruso C +4 more
doaj
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) [PDF]
Intra-abdominal infections (IAI) are an important cause of morbidity and are frequently associated with poor prognosis, particularly in high-risk patients.
A +173 more
core +4 more sources
Risk factors for Haemophilus influenzae and pneumococcal respiratory tract colonization in CVID [PDF]
To the Editor: Disease-specific studies focused on infection risk in common variable immune deficiencies (CVIDs) are needed to define strategies for controlling respiratory infections predominantly due to bacteria such as Streptococcus pneumoniae and ...
Camilli, Romina +10 more
core +1 more source
Selective pressure of beta-lactams is thought to be responsible for mutation selection in methicillin-susceptible Staphylococcus aureus (MSSA). We used next-generation sequencing to compare the genomes of beta-lactamase-positive (SA0707) and -negative ...
Vladimir Gostev +6 more
doaj +1 more source
Multiparametric determination of genes and their point mutations for identification of beta-lactamases [PDF]
More than half of all currently used antibiotics belong to the beta-lactam group, but their clinical effectiveness is severely limited by antibiotic resistance of microorganisms that are the causative agents of infectious diseases. Several mechanisms for
A. A. Medeiros +127 more
core +1 more source
Identification of drivers of mycobacterial resistance to peptidoglycan synthesis inhibitors
Beta-lactams have been excluded from tuberculosis therapy due to the intrinsic resistance of Mycobacterium tuberculosis (Mtb) to this antibiotic class, usually attributed to a potent beta-lactamase, BlaC, and to an unusually complex cell wall.
Francisco Olivença +8 more
doaj +1 more source
Draft Genome Sequences of Five Enterococcus Species Isolated from the Gut of Patients with Suspected Clostridium difficile Infection [PDF]
Indexación: Scopus.We present draft genome sequences of five Enterococcus species from patients suspected of Clostridium difficile infection. Genome completeness was confirmed by presence of bacterial orthologs (97%).
Baquedano, S. +5 more
core +1 more source
High potency of melaleuca alternifolia essential oil against multi-drug resistant gram-negative bacteria and methicillin-resistant staphylococcus aureus [PDF]
Purpose: Herein, an extended investigation of Tea tree oil (TTO) against a number of multi-drug resistant (MDR) microorganisms in liquid and vapor phases is reported.
Božović, Mijat +7 more
core +1 more source
This study aimed for the molecular detection of TEM and SHV genes in Extended-Spectrum beta-lactamases (ESBLs) clinical isolates of Enterobacteriace (Eshericichia coli, Klebsiella pneumoniae and Proteus spp.).
Ashraf Kadry +2 more
doaj +1 more source
Beta‐lactam versus beta‐ lactam/macrolide therapy in pediatric outpatient pneumonia [PDF]
SummaryObjectiveThe objective was to evaluate the comparative effectiveness of beta‐lactam monotherapy and beta‐ lactam/macrolide combination therapy in the outpatient management of children with community‐acquired pneumonia (CAP).MethodsThis retrospective cohort study included children, ages 1–18 years, with CAP diagnosed between January 1, 2008 and ...
Lilliam, Ambroggio +6 more
openaire +2 more sources

