Results 11 to 20 of about 60,277 (349)

Beta-lactam-induced pyrexia [PDF]

open access: bronzeJournal of the Intensive Care Society, 2016
Martha Belete, Colin Bigham
openalex   +4 more sources

Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus

open access: yesFrontiers in Molecular Biosciences, 2021
Methicillin-resistant S. aureus (MRSA) are resistant to beta-lactams, but synergistic activity between beta-lactams and glycopeptides/lipopeptides is common.
Rutan Zhang   +9 more
doaj   +1 more source

Which Are the Best Regimens of Broad-Spectrum Beta-Lactam Antibiotics in Burn Patients? A Systematic Review of Evidence from Pharmacology Studies

open access: yesAntibiotics, 2023
Background: Burn injury causes profound pathophysiological changes in the pharmacokinetic/pharmacodynamic (PK/PD) properties of antibiotics. Infections are among the principal complications after burn injuries, and broad-spectrum beta-lactams are the ...
Gianpiero Tebano   +6 more
doaj   +1 more source

Synthesis and penicillin‐binding protein inhibitory assessment of dipeptidic 4‐phenyl‐β‐lactams from α‐amino acid‐derived imines [PDF]

open access: yes, 2020
Monocyclic beta-lactams revive the research field on antibiotics, which are threatened by the emergence of resistant bacteria. A six-step synthetic route was developed, providing easy access to new 3-amino-1-carboxymethyl-4-phenyl-beta-lactams, of which ...
Amoroso, Ana Maria   +7 more
core   +2 more sources

Characterization and molecular epidemiology of Staphylococcus aureus strains resistant to beta-lactams isolated from the milk of cows diagnosed with subclinical mastitis [PDF]

open access: yesVeterinary World, 2019
Background and Aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp., which is ...
Geziella Áurea Aparecida Damasceno Souza   +6 more
doaj   +1 more source

Triple oral beta-lactam containing therapy for Buruli ulcer treatment shortening. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2019
The potential use of clinically approved beta-lactams for Buruli ulcer (BU) treatment was investigated with representative classes analyzed in vitro for activity against Mycobacterium ulcerans.
María Pilar Arenaz-Callao   +5 more
doaj   +1 more source

Disparities in antimicrobial consumption and resistance within a country: the case of beta-lactams in Argentina

open access: yesRevista Panamericana de Salud Pública, 2021
Objective. To describe bacterial resistance and antimicrobial consumption ratio at the subnational level in Argentina during 2018, considering beta-lactams group as a case-study. Methods.
Silvia Boni   +8 more
doaj   +1 more source

Beta-Lactamase Repressor BlaI Modulates Staphylococcus aureus Cathelicidin Antimicrobial Peptide Resistance and Virulence. [PDF]

open access: yes, 2015
BlaI is a repressor of BlaZ, the beta-lactamase responsible for penicillin resistance in Staphylococcus aureus. Through screening a transposon library in S.
Gallo, Richard L   +6 more
core   +7 more sources

Patterns and outcomes of empirical antimicrobial use in elderly outpatients: A pilot observational study from North India

open access: yesJournal of the Indian Academy of Geriatrics, 2022
Introduction: Despite the rampant use of antimicrobials in health-care settings, the safety and clinical outcome data of antimicrobials are scarce in the elderly population.
Bisweswar Ojha   +3 more
doaj   +1 more source

Barriers and facilitators for therapeutic drug monitoring of beta-lactams and ciprofloxacin in the ICU: a nationwide cross-sectional study

open access: yesBMC Infectious Diseases, 2022
Background Recent studies demonstrated that failure of achieving pharmacodynamic targets of commonly used antibiotics is common in critically ill patients.
Tim M. J. Ewoldt   +10 more
doaj   +1 more source

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