Results 11 to 20 of about 612,998 (297)

Clinical aspects of severe cutaneous adverse reactions caused by beta-lactam antibiotics: A study from the Korea SCAR registry

World Allergy Organization Journal, 2023
Background: Although beta-lactams are 1 of the major causative agents of severe cutaneous adverse reactions (SCAR), their epidemiology and clinical aspects have been poorly studied.
Min-Hye Kim, MD, PhD, Dong Yoon Kang, MD, PhD, Young-Hee Nam, MD, PhD, Da Woon Sim, MD, PhD, Sujeong Kim, MD, Jun Kyu Lee, MD, PhD, Jung-Won Park, MD, PhD, Hye-Kyung Park, MD, PhD, Jae-Woo Jung, MD, PhD, Cheol-Woo Kim, MD, PhD, Min-Suk Yang, MD, PhD, Joo-Hee Kim, MD, PhD, Young-Min Ye, MD, PhD, Young-Il Koh, MD, PhD, Hye-Ryun Kang, MD, PhD, Seoung Ju Park, Sae-Hoon Kim   +16 more
doaj   +1 more source

Uncovering Beta-Lactam Susceptibility Patterns in Clinical Isolates of Mycobacterium tuberculosis through Whole-Genome Sequencing [PDF]

, 2022
The increasing threat of drug resistance and a stagnated pipeline of novel therapeutics endanger the eradication of tuberculosis. Beta-lactams constitute promising additions to the current therapeutic arsenal and two carbapenems are included in group C ...
Olivença, Francisco, Silveiro, Cátia, Catalão, Maria João, Miragaia, Maria, Gomes, João Paulo, Nunes, Alexandra, Macedo, Rita, Pires, David, Anes, Elsa   +8 more
core   +1 more source

Synergy Between Beta-Lactams and Lipo-, Glyco-, and Lipoglycopeptides, Is Independent of the Seesaw Effect in Methicillin-Resistant Staphylococcus aureus

Frontiers in Molecular Biosciences, 2021
Methicillin-resistant S. aureus (MRSA) are resistant to beta-lactams, but synergistic activity between beta-lactams and glycopeptides/lipopeptides is common.
Rutan Zhang, Ismael A. Barreras Beltran, Nathaniel K. Ashford, Kelsi Penewit, Adam Waalkes, Elizabeth A. Holmes, Kelly M. Hines, Stephen J. Salipante, Libin Xu, Brian J. Werth   +9 more
doaj   +1 more source

Which Are the Best Regimens of Broad-Spectrum Beta-Lactam Antibiotics in Burn Patients? A Systematic Review of Evidence from Pharmacology Studies

Antibiotics, 2023
Background: Burn injury causes profound pathophysiological changes in the pharmacokinetic/pharmacodynamic (PK/PD) properties of antibiotics. Infections are among the principal complications after burn injuries, and broad-spectrum beta-lactams are the ...
Gianpiero Tebano, Giulia la Martire, Luigi Raumer, Monica Cricca, Davide Melandri, Federico Pea, Francesco Cristini   +6 more
doaj   +1 more source

Characterization and molecular epidemiology of Staphylococcus aureus strains resistant to beta-lactams isolated from the milk of cows diagnosed with subclinical mastitis [PDF]

Veterinary World, 2019
Background and Aim: The term ESKAPE, recognized by the WHO, is an acronym, which refers to the pathogens Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp., which is ...
Geziella Áurea Aparecida Damasceno Souza, Anna Christina de Almeida, Mauro Aparecido de Sousa Xavier, Lívia Mara Vitorino da Silva, Cintya Neves Sousa, Demerson Arruda Sanglard, Alessandra Rejane Ericsson de Oliveira Xavier   +6 more
doaj   +1 more source

Triple oral beta-lactam containing therapy for Buruli ulcer treatment shortening. [PDF]

PLoS Neglected Tropical Diseases, 2019
The potential use of clinically approved beta-lactams for Buruli ulcer (BU) treatment was investigated with representative classes analyzed in vitro for activity against Mycobacterium ulcerans.
María Pilar Arenaz-Callao, Rubén González Del Río, Ainhoa Lucía Quintana, Charles J Thompson, Alfonso Mendoza-Losana, Santiago Ramón-García   +5 more
doaj   +1 more source

Disparities in antimicrobial consumption and resistance within a country: the case of beta-lactams in Argentina

Revista Panamericana de Salud Pública, 2021
Objective. To describe bacterial resistance and antimicrobial consumption ratio at the subnational level in Argentina during 2018, considering beta-lactams group as a case-study. Methods.
Silvia Boni, Gustavo H. Marin, Laura Campaña, Lupe Marin, Alejandra Corso, Soledad Risso-Patron, Fernanda Gabriel, Valeria Garay, Manuel Limeres   +8 more
doaj   +1 more source

Patterns and outcomes of empirical antimicrobial use in elderly outpatients: A pilot observational study from North India

Journal of the Indian Academy of Geriatrics, 2022
Introduction: Despite the rampant use of antimicrobials in health-care settings, the safety and clinical outcome data of antimicrobials are scarce in the elderly population.
Bisweswar Ojha, Amit Singh, Sankha Shubhra Chakrabarti, Upinder Kaur   +3 more
doaj   +1 more source

Isothiourea-catalyzed asymmetric synthesis of β-lactams and β-amino esters from arylacetic acid derivatives and N-sulfonylaldimines [PDF]

, 2014
This work is supported by a Royal Society for a University Research Fellowship and the EPSRC and GSK (Case Award) as well as by the European Research Council under the European Unionʼs Seventh Framework Programme (FP7/2007-2013) (ERC Grant Agreement No ...
Prevet, Hugues, Shapland, Peter, Smith, Andrew D., Douglas, James, Smith, Siobhan R., Slawin, Alexandra M. Z.   +5 more
core   +1 more source

Barriers and facilitators for therapeutic drug monitoring of beta-lactams and ciprofloxacin in the ICU: a nationwide cross-sectional study

BMC Infectious Diseases, 2022
Background Recent studies demonstrated that failure of achieving pharmacodynamic targets of commonly used antibiotics is common in critically ill patients.
Tim M. J. Ewoldt, Alan Abdulla, Puck van den Broek, Nicole Hunfeld, Soma Bahmany, Anouk E. Muller, Diederik Gommers, Suzanne Polinder, Henrik Endeman, Inge Spronk, Birgit C. P. Koch   +10 more
doaj   +1 more source