Appropriateness of Antibiotic Prescriptions for Urinary Tract Infections [PDF]
Introduction: Urinary tract infections (UTI) are a common indication for antibiotic use in the emergency department (ED). With antibiotic resistance on the rise, it is essential that antibiotics be prescribed appropriately for UTIs.
Chardavoyne, Paige, Kasmire, Kathryn E.
core
Pyrolysis of azetidinone derivatives: a versatile route towards electron-rich alkenes, C-1 allylation and/or homologation of aldehydes [PDF]
Pyrolysis of beta-lactams and beta-thiolactams led essentially to stereoselective synthesis of the high energy electron-rich Z-alkenes. Extension of this methodology to the pyrolysis of 3-allyloxy derivatives gave a simple direct route to the ...
Al-Awadi, Nouria A. +4 more
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Evaluation of Risk Factors for Carbapenem-Resistant Klebsiella Pneumoniae Bacteremia
INTRODUCTION[|]In recent years, carbapenem-resistant Klebsiella pneumoniae infections have become an important health problem in our country and all over the world.
Pınar Kıran +2 more
doaj +1 more source
Image-based dynamic phenotyping reveals genetic determinants of filamentation-mediated beta-lactam tolerance [PDF]
Antibiotic tolerance characterized by slow killing of bacteria in response to a drug can lead to treatment failure and promote the emergence of resistance.
Camacho, Rafael +8 more
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Profile of Enterobacteria Resistant to Beta-Lactams
A serious emerging problem worldwide is increased antimicrobial resistance. Acquisition of coding genes for evasion methods of antimicrobial drug mechanisms characterizes acquired resistance. This phenomenon has been observed in Enterobacteriaceae family.
Andressa Liberal Santos +14 more
doaj +1 more source
Protein binding of β-lactam antibiotics in critically Ill patients: can we successfully predict unbound concentrations? [PDF]
The use of therapeutic drug monitoring (TDM) to optimize beta-lactam dosing in critically ill patients is growing in popularity, although there are limited data describing the potential impact of altered protein binding on achievement of target ...
Adnan, Syamhanin +6 more
core +1 more source
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández +6 more
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Right-sided native-valve infective endocarditis caused by : A case report
Streptococcus acidominimus is rarely pathogenic in humans. In the literature, there are only few cases related to S. acidominimus , including pneumonia, meningitis, brain abscess, pericarditis, sepsis, and endocarditis.
Liyana Arachchige Dona Thulini Madubashini +3 more
doaj +1 more source
Effect of β-lactamase inhibitors on in vitro activity of β-lactam antibiotics against Burkholderia cepacia complex species [PDF]
Background: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of beta-
Coenye, Tom, Everaert, Annelien
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Since the discovery 11 of the activating effect of the N- (p-Nitro-phenyl)-group on the methine hydrogen of halogenacetamino esters, it has been found that the p-Acetyl-phenyl and m-Nitro-phenyl groups exert a similar effect. It has been shown that the delocalisation of the N-non-bonded electrons across the orbitals of the N-Aryl substituent is the ...
B G, Chatterjee, R F, Abdulla
openaire +2 more sources

