Results 31 to 40 of about 827,661 (196)

Metallo-Beta-Lactamases: NDM

Journal of Education, Health and Sport, 2019
New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli. It determines these bacteria resistance to the majority of known antibiotics.
Kamil Leis, Ewelina Mazur, Paweł Szyperski, Patryk Kaczor, Michalina Kolan, Bartłomiej Wiśniewski, Magdalena Jabłońska, Aleksandra Kulczyńska, Aleksandra Baska, Jakub Kazik, Daria Bojczuk, Klaudyna Grzelakowska, Krystian Kałużny, Przemysław Gałązka   +13 more
doaj   +3 more sources

Inhibitors of metallo-beta-lactamases

, 2020
The present invention relates to compounds that function as inhibitors of metallo-beta-lactamases (MBL). The present invention also relates to pharmaceutical compositions comprising such MBL inhibitors, and uses thereof in the treatment of bacterial ...
Legru, Alice, Sevaille, Laurent, Gavara, Laurent, Docquier, Jean-Denis, Hernandez, Jean-François   +4 more
core   +2 more sources

Prevalence of co-existence genes and clonal spread of ESBL-producing isolates causing hospital and community-acquired infections in Zenica-Doboj Canton, Bosnia and Herzegovina

Journal of Health Sciences, 2017
Introduction: Co-existence type of ESBL-producing isolates are serious problem in the public health world. Methods Antibiotic susceptibility was determined by disc diffusion and broth microdilution according to CLSI guidelines.
Amir Ibrahimagić, Selma Uzunović, Branka Bedenić   +2 more
doaj   +1 more source

Exposure assessment of extended-spectrum beta-lactamases/AmpC beta-lactamases-producing in meat in Denmark [PDF]

, 2013
Extended-Spectrum Beta-Lactamases (ESBL) and AmpC Beta-Lactamases (AmpC) are of great concern because of their ability to cause antimicrobial resistance in Enterobacteriaceae hampering the effect of treatment with beta-lactam antibiotics.
da Costa, P., Nielsen, L., Alban, Lis, Carmo, L.   +3 more
core   +1 more source

Structural basis of metallo-β-lactamase, serine-β-lactamase and penicillin-binding protein inhibition by cyclic boronates

Nature Communications, 2016
Bacterial beta-lactamases are responsible for resistance to beta-lactams, the most important family of antibiotics. Here, the authors reveal cyclic boronate inhibitors that are active against both serine- and metallo-beta-lactamases and represent a ...
Jürgen Brem, Ricky Cain, Samuel Cahill, Michael A. McDonough, Ian J. Clifton, Juan-Carlos Jiménez-Castellanos, Matthew B. Avison, James Spencer, Colin W. G. Fishwick, Christopher J. Schofield   +9 more
doaj   +1 more source

Molecular epidemiology and resistance patterns of blaOXA-48 Klebsiella pneumoniae and Escherichia coli: A nationwide multicenter study in Taiwan

Journal of Microbiology, Immunology and Infection, 2021
Background: We describe the molecular epidemiology and resistance patterns of blaOXA-48 Klebsiella pneumoniae and Escherichia coli in Taiwan. Methods: In this multicenter surveillance study from January 2012 to August 2015, the identified blaOXA-48 ...
Ching-Hsun Wang, Ling Ma, Li-Yueh Huang, Kuo-Ming Yeh, Jung-Chung Lin, L. Kristopher Siu, Feng-Yee Chang   +6 more
doaj   +1 more source

Exposure assessment of extended-spectrum beta-lactamases/AmpC beta-lactamases-producing Escherichia coli in meat in Denmark [PDF]

, 2014
INTRODUCTION Extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases (AmpC) are of concern for veterinary and public health because of their ability to cause treatment failure due to antimicrobial resistance in Enterobacteriaceae.
da Costa, Paulo M, Gomes do Carmo, Luis Pedro, Nielsen, Liza Rosenbaum, Nielsen, Liza R, Alban, Lis, Carmo, Luís P., da Costa, Paulo M.   +6 more
core   +2 more sources

Ventilator-associated pneumonia in a tertiary care hospital in India: role of multi-drug resistant pathogens

Journal of Infection in Developing Countries, 2010
Background: Ventilator-Associated Pneumonia (VAP) is the most frequent intensive-care-unit (ICU)-acquired infection. The aetiology of VAP varies with different patient populations and types of ICUs.
Noyal Mariya Joseph, Sujatha Sistla, Tarun Kumar Dutta, Ashok Shankar Badhe, Desdemona Rasitha, Subhash Chandra Parija   +5 more
doaj   +1 more source

Beta lactamases mediated resistance amongst gram negative bacilli in burn infection [PDF]

International Journal of Biological and Medical Research, 2011
Introduction: Burn is one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality.
Nitin Bandekar, Vinodkumar CS, Basavarajappa KG, Prabhakar PJ, Nagaraj P   +1 more
doaj  

Dd-Peptidases and Beta-Lactamases: Catalytic Mechanisms and Specificities

, 1995
peer reviewedDD-peptidases and beta-lactamases share several common properties, including the formation of an acylenzyme intermediate in their catalytic pathways.
Amicosante, G., Lamotte-Brasseur, Josette, Fonze, E., Galleni, Moreno, Frère, Jean-Marie, Raquet, X.   +5 more
core   +1 more source