Extended-spectrum beta-lactamases: the European experience [PDF]
Extended-spectrum beta-lactamases mediate resistance to cephalosporin antibiotics and were first discovered in Europe in the early 1980s. They have become a widespread problem, particularly in Klebsiella pneumoniae, but increasingly in non-typhoid ...
Paterson, D.L., David L. Paterson
core +1 more source
Background: Ventilator-Associated Pneumonia (VAP) is the most frequent intensive-care-unit (ICU)-acquired infection. The aetiology of VAP varies with different patient populations and types of ICUs.
Noyal Mariya Joseph +5 more
doaj +1 more source
Exposure assessment of extended-spectrum beta-lactamases/AmpC beta-lactamases-producing in meat in Denmark [PDF]
Extended-Spectrum Beta-Lactamases (ESBL) and AmpC Beta-Lactamases (AmpC) are of great concern because of their ability to cause antimicrobial resistance in Enterobacteriaceae hampering the effect of treatment with beta-lactam antibiotics.
da Costa, P. +3 more
core +2 more sources
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis +5 more
wiley +1 more source
Beta lactamases mediated resistance amongst gram negative bacilli in burn infection [PDF]
Introduction: Burn is one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality.
Nitin Bandekar +1 more
doaj
Interaction between Class B Beta-Lactamases and Suicide Substrates of Active-Site Serine Beta-Lactamases [PDF]
peer reviewedThe most widely used inactivators of active-site serine beta-lactamases behave as substrates of four class B metallo-beta-lactamases, but the efficiency of the catalytic process can vary by several orders of magnitude.
Valladares, M. H. +19 more
core +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes [PDF]
The environment harbours a significant diversity of uncultured bacteria and a potential source of novel and extant resistance genes which may recombine with clinically important bacteria disseminated into environmental reservoirs.
Hawkey, PM +19 more
core +1 more source
The impact of long-distance mutations on the Ω-loop conformation in TEM type β-lactamases [PDF]
β-lactamases are hydrolytic enzymes primarily responsible for occurrence and abundance of bacteria resistant to β-lactam antibiotics. TEM type β-lactamases are formed by the parent enzyme TEM-1 and more than two hundred of its mutants.
Dmitrii Shcherbinin (6881894) +4 more
core +1 more source
Explaining Adherence Success in Sub-Saharan Africa: An Ethnographic Study. [PDF]
Individuals living with HIV/AIDS in sub-Saharan Africa generally take more than 90% of prescribed doses of antiretroviral therapy (ART). This number exceeds the levels of adherence observed in North America and dispels early scale-up concerns that ...
Agbaji Oche +31 more
core +1 more source

