Results 51 to 60 of about 597,070 (286)
, 2014 The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Benjamin A. Evans (3115968) +3 more
core +1 more source
Journal of Applied Oral Science, 2007 Endodontic infections are mixed aerobic-anaerobic infections and several microbial groups associated to these pathologies are also involved in orofacial infections. The goal of this study was to evaluate the susceptibility of microorganisms isolated from
Elerson Gaetti-Jardim Júnior +4 more
doaj +1 more source
Correlation of the effect of beta-lactamase inhibitors on the beta-lactamase in growing cultures of gram-negative bacteria with their effect on the isolated beta-lactamase [PDF]
Antimicrobial Agents and Chemotherapy, 1984 The effectiveness of clavulanic acid, sulbactam, quinacillin sulfone, and the carbapenems MM13902 and MM4550 as inhibitors of TEM-2 beta-lactamase in growing cultures of gram-negative bacteria has been studied. Each of these beta-lactams inhibited the enzyme in intact cells, and the nature of the inhibition correlated with studies on the purified ...
C J, Easton, J R, Knowles
openaire +2 more sources
Estudo de isolados clínicos de Pseudomonas aeruginosa multirresistentes e produtores de metalo-ß-lactamases [PDF]
, 2011 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2011Nas últimas duas décadas, índices crescentes de resistência têm minado a eficácia
Guarneri, Rômulo
core
Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli [PDF]
Journal of Bacteriology, 1976 A plasmid, derived from a naturally occurring strain of Proteus mirabilis, conferred resistance to cephalosporins, apparently mediated by a beta-lactamase indistinguishable from that determined by the chromosomal gene of Escherichia coli K-12. There was evidence for a recombination event between the wild-type plasmid and a defective F factor (Fsp) in ...
BOBROWSKI, MM +8 more
openaire +3 more sources
Dd-Peptidases and Beta-Lactamases: Catalytic Mechanisms and Specificities [PDF]
, 1995 peer reviewedDD-peptidases and beta-lactamases share several common properties, including the formation of an acylenzyme intermediate in their catalytic pathways.
Amicosante, G. +5 more
core +1 more source
Muller Journal of Medical Sciences and Research, 2016 Introduction: Pseudomonas aeruginosa is one of the major etiological agents of nosocomial infection. They are difficult to treat as the majority of them exhibit varying degrees of innate resistance.
Subbalakshmi Easwaran +2 more
doaj +1 more source
Journal of Applied Sciences and Environmental Management, 2020 The presence of integrons and antibiotic resistance genes in the genome of Pseudomonas aeruginosa pose a serious problem in the treatment and control of infections caused by this pathogen in hospitals.
B.O. Isichei-Ukah, O.I. Enabulele
doaj +1 more source
Catalytic Properties of Class a Beta-Lactamases: Efficiency and Diversity [PDF]
, 1998 peer reviewedbeta-Lactamases are the main cause of bacterial resistance to penicillins, cephalosporins and related beta-lactam compounds. These enzymes inactivate the antibiotics by hydrolysing the amide bond of the beta-lactam ring.
Lamotte-Brasseur, Josette +2 more
core +1 more source
Animal Research and One Health, EarlyView.Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source