Results 61 to 70 of about 827,661 (196)
Identification of group specific motifs in Beta-lactamase family of proteins
Background Beta-lactamases are one of the most serious threats to public health. In order to combat this threat we need to study the molecular and functional diversity of these enzymes and identify signatures specific to these enzymes.
Saxena Akansha +2 more
doaj +1 more source
Acute thrombocytosis in a patient treated with ertapenem
Ertapenem, a carbapenem-type beta-lactam antibiotic, demonstrates broad-spectrum efficacy against a wide range of Gram-positive and Gram-negative bacteria, including aerobes and anaerobes.
Edward K. Sarfo +3 more
doaj +1 more source
Primers for Use in Detecting Beta- Lactamases
Oliognucleotide primers are provided that are specific for nucleic acid characteristic of certain beta-lactamases. The primers can be employed in methods to identify nucleic acid characteristic of family-specific beta-lactamase enzymes in samples, and ...
Hanson, Nancy D. +2 more
core +1 more source
Extended-spectrum beta-lactamases: the European experience
Extended-spectrum beta-lactamases mediate resistance to cephalosporin antibiotics and were first discovered in Europe in the early 1980s. They have become a widespread problem, particularly in Klebsiella pneumoniae, but increasingly in non-typhoid ...
Paterson, D.L., David L. Paterson
core +1 more source
Allergic Reactions and Cross-Reactivity Potential with Beta-Lactamase Inhibitors
Although beta-lactam allergies are an emerging focus of stewardship programs and interventions, less is publicly released regarding allergies to beta-lactamase inhibitors. This review presents and evaluates the data regarding allergic reactions with beta-
Kayla R. Stover +2 more
doaj +1 more source
COMPARACIÓN DE LA PRUEBA TRIDIMENSIONAL CON PCR MÚLTIPLE, PARA DETECCIÓN DE CARBAPENEMASAS
Objective: To compare the phenotypic test for detection of carbapenemases (Three-dimensional Test - THT), with molecular biology test (Multiplex PCR), for the detection of resistance genes.
María Isabel Múnera-Jaramillo
doaj +1 more source
Beta-lactamases from Yersinia enterocolitica
Two beta-lactamases, A and B, have been shown to be present in a strain of Yersinia enterocolitica (w222). Beta-Lactamase A hydrolyses a variety of penicillins and cephalosporins. This enzyme is sensitive to thiol reagents, is only partially inhibited by
Cornelis, G +3 more
core
Beta-lactamases in anaerobic, intestinal bacteria: a narrative review
Anaerobic bacteria in the human intestinal microbiota play a pivotal role in antibiotic resistance, primarily through the production of beta-lactamases. This narrative review explores the diversity of beta-lactamases found in intestinal anaerobes, their ...
Dutkiewicz Marion +2 more
core +1 more source
Metallo-beta-lactamases: a last frontier for beta-lactams?
Metallo-beta-lactamases are resistance determinants of increasing clinical relevance in Gram-negative bacteria. Because of their broad range, potent carbapenemase activity and resistance to inhibitors, these enzymes can confer resistance to almost all ...
Giamarellou, Helen +2 more
core
Métodos de pesquisa de beta-lactamases em amostras clínicas: estudo de revisão [PDF]
Trabalho apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas.As beta-lactamases são enzimas bacterianas que hidrolisam antibióticos beta-lactâmicos.
Gralha, Rita Emanuela Fernandes
core +1 more source

