Results 61 to 70 of about 597,070 (286)
Journal of the Scientific Society, 2013 Background: Resistance to broad-spectrum beta-lactams, mediated by extended-spectrum beta-lactamases (ESBL), AmpC beta-lactamase, and metallo-beta-lactamase (MBL) enzymes, is an increasing problem worldwide. Aim of the study: This study was undertaken to
Varun Goel +2 more
doaj +1 more source
Beta-lactamase resistance genes in Enterobacteriaceae from Nigeria
African Journal of Laboratory Medicine, 2022 Background: Beta-lactamase genes are one of the most important groups of antimicrobial resistance genes in human and animal health. Therefore, continuous surveillance of this group of resistance genes is needed for a better understanding of the local ...
Babafela B. Awosile +4 more
doaj +1 more source
BMEMat, EarlyView.LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng +4 more
wiley +1 more source
Prevalence of Extended-Spectrum Beta-Lactamases in Enterobacter Cloacae in Taiwan and Comparison of 3 Phenotypic Confirmatory Methods for Detecting Extended-Spectrum Beta-Lactamase Production [PDF]
, 2011 Background and purpose: The prevalence of extended-spectrum beta- lactamases (ESBLs) in Enterobacter cloacae remains unclear in Taiwan. This study was conducted to investigate the prevalence of ESBL-producing E cloacae in Taiwan.
YANG, JIA-LING;WANG, JANN-TAY;YANG, LAUDERDALE TSAI-LING;CHANG, SHAN-CHWEN +1 more
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Design, Molecular Docking, Synthesis of Aromatic Amino Acids Linked to Cephalexin.
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Infections caused by bacteria have a significant impact on public health. Chemical synthesis of new derivatives of cephalexin inked to amino acid (tryptophan or histidine) through an amide bond at the acyl side chain is achieved.
Yasir F. Muhsin +2 more
doaj +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, EarlyView.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó +7 more
wiley +1 more source
beta-Lactamases evolve against antibiotics by acquiring large active-site electric fields [PDF]
, 2022 A compound bound covalently to an enzyme active site can act either as a substrate if the covalent linkage is readily broken up by the enzyme or as an inhibitor if the bond dissociates slowly.
Zhe, Ji, Steven, Boxer
core +1 more source
Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications
Environmental Progress &Sustainable Energy, EarlyView.Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu +6 more
wiley +1 more source
Structure based drug design: the discovery of novel inhibitors active against New Delhi Metallo-β-lactamase-1 [PDF]
, 2017 Background. The emergence of bacterial strains resistant to available antibiotic armamentarium is nowadays a pressing issue in clinical therapy. Among the several mechanisms of bacterial resistance, the rapid evolution and spread of carbapenemases, β ...
Cross, Simon +7 more
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