Results 61 to 70 of about 1,753,858 (323)
Design, Molecular Docking, Synthesis of Aromatic Amino Acids Linked to Cephalexin.
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Infections caused by bacteria have a significant impact on public health. Chemical synthesis of new derivatives of cephalexin inked to amino acid (tryptophan or histidine) through an amide bond at the acyl side chain is achieved.
Yasir F. Muhsin +2 more
doaj +1 more source
Plasmid-determined beta-lactamase indistinguishable from the chromosomal beta-lactamase of Escherichia coli [PDF]
Journal of Bacteriology, 1976 A plasmid, derived from a naturally occurring strain of Proteus mirabilis, conferred resistance to cephalosporins, apparently mediated by a beta-lactamase indistinguishable from that determined by the chromosomal gene of Escherichia coli K-12. There was evidence for a recombination event between the wild-type plasmid and a defective F factor (Fsp) in ...
BOBROWSKI, MM +8 more
openaire +3 more sources
Catalytic Properties of Class a Beta-Lactamases: Efficiency and Diversity [PDF]
, 1998 peer reviewedbeta-Lactamases are the main cause of bacterial resistance to penicillins, cephalosporins and related beta-lactam compounds. These enzymes inactivate the antibiotics by hydrolysing the amide bond of the beta-lactam ring.
Lamotte-Brasseur, Josette +2 more
core +1 more source
Animal Research and One Health, EarlyView.Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source
Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, EarlyView.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Beta-lactamase resistance genes in Enterobacteriaceae from Nigeria
African Journal of Laboratory Medicine, 2022 Background: Beta-lactamase genes are one of the most important groups of antimicrobial resistance genes in human and animal health. Therefore, continuous surveillance of this group of resistance genes is needed for a better understanding of the local ...
Babafela B. Awosile +4 more
doaj +1 more source
Antibacterial Activity of Heteropolytungstates Against Proteus mirabilis
European Journal of Inorganic Chemistry, EarlyView.We investigated the in vitro antibacterial activity of several heteropolytungstates against P. mirabilis, a drug‐resistant pathogen. All tested polyanions inhibited bacterial growth, with the Preyssler–Pope–Jeannin polyanion P5W30 exhibiting the highest activity (MIC = 0.78 mg/mL).
Nour El Ghouch +5 more
wiley +1 more source
Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications
Environmental Progress &Sustainable Energy, EarlyView.Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu +6 more
wiley +1 more source
Extended-spectrum beta-lactamases: the European experience
, 2001 Extended-spectrum beta-lactamases mediate resistance to cephalosporin antibiotics and were first discovered in Europe in the early 1980s. They have become a widespread problem, particularly in Klebsiella pneumoniae, but increasingly in non-typhoid ...
Paterson, D.L., David L. Paterson
core +1 more source
Vaginal host–microbe signatures linked to placental outcomes in mares
Equine Veterinary Journal, EarlyView.Abstract Background Ascending placentitis is a leading cause of late‐term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined.
Machteld van Heule +7 more
wiley +1 more source