Results 81 to 90 of about 781,021 (270)

The .BETA.-lactamases of genus Bacteroides.

open access: yesThe Journal of Antibiotics, 1983
Two hundred anaerobic isolates from clinical specimens were examined for beta-lactamase production by Nitrocefin methodology. Altogether, 77 strains were beta-lactamase producers. Organisms belonging to Bacteroides melaninogenicus group, i.e., B. intermedius and B.
M, Tajima, K, Sawa, K, Watanabe, K, Ueno
openaire   +3 more sources

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi   +4 more
wiley   +1 more source

Escape mutations circumvent a tradeoff between resistance to a beta-lactam and resistance to a beta-lactamase inhibitor

open access: yesNature Communications, 2020
Beta-lactam antibiotics and beta-lactamase inhibitors compete for the same binding site on beta-lactamases; thus, mutations that increase beta-lactamase activity likely increase also susceptibility to the inhibitor. Here, Russ et al.
Dor Russ   +8 more
doaj   +1 more source

Filtration‐Based SERS With In Situ Gold Growth in Bacterial Microenvironment for Rapid Detection of Low‐Level Bacteria

open access: yesSmall Methods, EarlyView.
A filtration‐assisted SERS platform integrating in situ gold growth within the bacterial microenvironment enables rapid and highly sensitive detection of low‐level bacteria in complex biological matrices. By overcoming hotspot–bacteria mismatch, the platform simultaneously achieves selective bacterial identification and rapid antimicrobial ...
Eun‐Bi Jang   +3 more
wiley   +1 more source

Massive culture-based approach for the screening of AmpC, ESBL, and carbapenemase producers from rectal swabs

open access: yesMicrobiology Spectrum
Gram-negative bacilli-producing beta-lactamases are major causes of difficult-to-treat infections, especially the AmpC, extended-spectrum beta-lactamases (ESBL), and carbapenemase types. Their spread within and outside hospital settings demands effective
Gabriel Taddeucci-Rocha   +6 more
doaj   +1 more source

Identification of extended spectrum beta lactamases, AmpC and carbapenemase production among isolates of Escherichia coli in North Indian tertiary care centre

open access: yesAvicenna Journal of Medicine, 2018
Introduction: Identification of Extended spectrum beta lactamases (ESBL), AmpC production and carbapenemase production among isolates of Escherichia coli, helps clinician to rationalize the choice of antibiotics.
Uma Chaudhary   +2 more
doaj   +1 more source

Extended-spectrum beta-lactamases: the European experience

open access: yes, 2001
Extended-spectrum beta-lactamases mediate resistance to cephalosporin antibiotics and were first discovered in Europe in the early 1980s. They have become a widespread problem, particularly in Klebsiella pneumoniae, but increasingly in non-typhoid ...
Paterson, D.L., David L. Paterson
core   +1 more source

Isolation of carbapenem‐resistant Pseudomonas aeruginosa and other Gram‐negative ESKAPE organisms from samples of raw‐meat diets for dogs in the UK

open access: yesVeterinary Record, EarlyView.
Abstract Background Gram‐negative ESKAPE organisms are an emerging threat in veterinary medicine that also have zoonotic potential. However, little is known about the prevalence and risks of these organisms in pet food. We present the incidental finding of gram‐negative ESKAPE organisms within samples of raw meat diets for dogs in the United Kingdom ...
Genever Morgan   +5 more
wiley   +1 more source

Evolutionary and Epidemiological Characterization of Multidrug‐Resistant Escherichia coli Isolated From Pangolins in China

open access: yesIntegrative Zoology, EarlyView.
ABSTRACT Malayan pangolin populations have fallen to a critically endangered level, and illegal trafficking of wild pangolins is a global problem. Little is known about antimicrobial‐resistant bacteria (MDRB) harbored by pangolins, although pangolins are frequently consumed as food or used in traditional medicine. In this study, we report for the first
Yawen Wang   +8 more
wiley   +1 more source

Evaluation of phenotypic tests for the detection of AmpC beta-lactamase in clinical isolates of Escherichia coli

open access: yesIndian Journal of Pathology and Microbiology, 2013
Background: AmpC beta lactamases are cephalosporinases that confer resistance to a wide range of beta lactam drugs thereby causing serious therapeautic problem.
Deepika Handa   +5 more
doaj   +1 more source

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