Results 91 to 100 of about 1,753,858 (323)

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source

Phenotypic characterization of beta-lactamases producing Gram-negative bacteria in a tertiary hospital, Nepal

Nepal Journal of Biotechnology, 2019
Infections caused by beta-lactamases producing Gram-negative bacteria are increasing, thus posing a challenge to the management of such infections.
Elina Maharjan, Pooja Shakya, Balkrishna Bhattachan, Bharat Prasad Baral, Dhiraj Shrestha   +4 more
doaj   +1 more source

Evaluation of phenotypic tests for the detection of AmpC beta-lactamase in clinical isolates of Escherichia coli

Indian Journal of Pathology and Microbiology, 2013
Background: AmpC beta lactamases are cephalosporinases that confer resistance to a wide range of beta lactam drugs thereby causing serious therapeautic problem.
Deepika Handa, Anita Pandey, Ashish Kumar Asthana, Ashutosh Rawat, Seemant Handa, Bhaskar Thakuria   +5 more
doaj   +1 more source

Inhibitors of metallo-beta-lactamases

, 2020
The present invention relates to compounds that function as inhibitors of metallo-beta-lactamases (MBL). The present invention also relates to pharmaceutical compositions comprising such MBL inhibitors, and uses thereof in the treatment of bacterial ...
Legru, Alice, Sevaille, Laurent, Gavara, Laurent, Docquier, Jean-Denis, Hernandez, Jean-François   +4 more
core  

OXA β-lactamases

, 2014
The OXA β-lactamases were among the earliest β-lactamases detected; however, these molecular class D β-lactamases were originally relatively rare and always plasmid mediated.
Benjamin A. Evans (3115968), Evans, Benjamin A, Amyes, Sebastian G B, Sebastian G. B. Amyes (16653285)   +3 more
core   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Identification of group specific motifs in Beta-lactamase family of proteins

Journal of Biomedical Science, 2009
Background Beta-lactamases are one of the most serious threats to public health. In order to combat this threat we need to study the molecular and functional diversity of these enzymes and identify signatures specific to these enzymes.
Saxena Akansha, Singh Reema, Singh Harpreet   +2 more
doaj   +1 more source

Dd-Peptidases and Beta-Lactamases: Catalytic Mechanisms and Specificities

, 1995
peer reviewedDD-peptidases and beta-lactamases share several common properties, including the formation of an acylenzyme intermediate in their catalytic pathways.
Amicosante, G., Lamotte-Brasseur, Josette, Fonze, E., Galleni, Moreno, Frère, Jean-Marie, Raquet, X.   +5 more
core   +1 more source

Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference

Microbiota Medicine Research, EarlyView.
ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang, Sunny Hei Wong, Gaochen Lu, Zheshun Pi, Ting Zhang, Hon Ho Yu, Nan Bu, Xiong Chen, Bota Cui, Dafa Ding, Hainv Gao, Suyu He, Xingxiang He, Shengjuan Hu, Jia Hu, Yunlian Hu, Xiaomeng Jiang, Jiang Jin, Jingnan Li, Pan Li, Juan Liao, Weiwei Liao, Jiang Liu, Ling Liu, Yaping Liu, Yanyan Liu, Yu Liu, Muhan Lv, Xiangjun Meng, Yongzhan Nie, Qian Ren, Lixuan Sang, Yang Sun, Xiaowen Tang, Liangjing Wang, Wei Wang, Xin Wang, Yanling Wei, Quan Wen, Lihao Wu, Xia Wu, Fang Xiao, Lijing Xiong, Shaoqi Yang, Song Yang, Guoliang Ye, Yue Zeng, Huihong Zhai, Xiaoqian Zhang, Yu Zhang, Kun Zhao, Li Zhou, Li Zhu, Kaichun Wu   +53 more
wiley   +1 more source