Results 21 to 30 of about 1,753,858 (323)
Exposure assessment of extended-spectrum beta-lactamases/AmpC beta-lactamases-producing Escherichia coli in meat in Denmark [PDF]
, 2014 INTRODUCTION Extended-spectrum beta-lactamases (ESBL) and AmpC beta-lactamases (AmpC) are of concern for veterinary and public health because of their ability to cause treatment failure due to antimicrobial resistance in Enterobacteriaceae.
da Costa, Paulo M +6 more
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Beta-lactamase induction and cell wall metabolism in Gram-negative bacteria
Frontiers in Microbiology, 2013 Production of beta-lactamases, the enzymes that degrade beta-lactam antibiotics, is the most widespread and threatening mechanism of antibiotic resistance.
Ximin eZeng, Jun eLin
doaj +1 more source
Cefotaxime/sulbactam: clinical and pharmacological characteristics [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 The recently approved cefotaxime/sulbactam, combination of third-generation cephalosporin (cefotaxime) and beta-lactamase inhibitor (sulbactam), can combat resistance mechanisms associated with the production of serine beta-lactamases, including some ...
Ortenberg E.A., Golub A.V.
doaj +1 more source
PLoS ONE, 2020 BackgroundExtended spectrum Beta-lactamases (ESBLs) and AmpC beta-lactamases (AmpC) are the common enzymes produced by gram negative bacilli, which are their main mechanisms of resistance to all generations of cephalosporins.
Saba Gebremichael Tekele +4 more
doaj +1 more source
Journal of Education, Health and Sport, 2019 New Delhi, an enzyme belonging to the Metallo-beta-lactamases and Carbapenemases group, is most commonly found in Klebsiella pneumoniae and Escherichia coli. It determines these bacteria resistance to the majority of known antibiotics.
Kamil Leis +13 more
doaj +3 more sources
Exploring Protein Sequence Space Using Computationally Directed Recombination [PDF]
, 2006 Evolution has provided us with many protein sequences. However, these sequences represent a very small fraction of the possible sequences. In the laboratory, scientists have explored areas of sequence space not represented by natural proteins both to ...
Meyer, Michelle Margaret
core +1 more source
A Primer on AmpC Beta-Lactamases: Necessary Knowledge for an Increasingly Multidrug-Resistant World.
Clinical Infectious Diseases, 2019 Understanding the nuances of AmpC β-lactamase mediated resistance can be challenging - even for the infectious diseases specialist. AmpC resistance can be classified into three categories: (a) inducible chromosomal resistance that emerges in the setting ...
P. Tamma +7 more
semanticscholar +1 more source
The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
, 2008 Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
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The Growing Genetic and Functional Diversity of Extended Spectrum Beta-Lactamases
BioMed Research International, 2018 The β-lactams—a large class of diverse compounds—due to their excellent safety profile and broad antimicrobial spectrum are considered to be the most widely used therapeutic class of antibacterials prescribed in human and veterinary clinical practices ...
S. ur Rahman +5 more
semanticscholar +1 more source
Journal of Health Sciences, 2017 Introduction: Co-existence type of ESBL-producing isolates are serious problem in the public health world. Methods Antibiotic susceptibility was determined by disc diffusion and broth microdilution according to CLSI guidelines.
Amir Ibrahimagić +2 more
doaj +1 more source