Results 41 to 50 of about 24,917 (198)
Global emergence of carbapenem-resistant Klebsiella pneumoniae co-carrying multiple carbapenemases
Computational and Structural Biotechnology Journal, 2023 The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) co-carrying multiple carbapenemases is complicating clinical treatment. This study aimed to investigate the global dissemination trends of CRKP strains that co-carry multiple ...
Hao Guo +5 more
semanticscholar +1 more source
The CARBA-MAP study: national mapping of carbapenemases in Spain (2014–2018)
Frontiers in Microbiology, 2023 Introduction Infections caused by carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa, including isolates producing acquired carbapenemases, constitute a prevalent health problem worldwide. The primary objective of
I. Gracia-Ahufinger +40 more
semanticscholar +1 more source
Clinical Microbiology and Infection, 2023 OBJECTIVES To analyse carbapenemases in Proteus mirabilis and assess the performance of carbapenemase detection assays. METHODS Eighty-one clinical P. mirabilis isolates with high-level resistance at least to ampicillin (>32 mg/L) or previous detection
A. Hamprecht +7 more
semanticscholar +1 more source
Frontiers in Cellular and Infection Microbiology, 2020 This study aimed to investigate the dissemination and characteristics of blaKPC, blaNDM, blaOXA-48-like, blaIMP, and blaVIM among the carbapenem-resistant Enterobacteriaceae (CRE) strains isolated from adult and children patients.
Ren-Ru Han +9 more
semanticscholar +1 more source
CRISPR-Cas13a-Based Assay for Accurate Detection of OXA-48 and GES Carbapenemases
Microbiology spectrum, 2023 Carbapenems are one of the last-resort antibiotics for defense against multidrug-resistant pathogens. Multiple nucleic acid amplification methods, including multiplex PCR, multiplex loop-mediated isothermal amplification (LAMP) and multiplex RPAs, can ...
C. Ortiz-Cartagena +16 more
semanticscholar +1 more source
Journal of Antimicrobial Chemotherapy, 2006 In recent years, the number of class D beta-lactamases with carbapenem-hydrolysing properties has increased substantially. Based on amino acid sequence identities, these class D or OXA-type carbapenemases are divided into eight distantly related groups, and they are only remotely related to other class D beta-lactamases.
Walther-Rasmussen, J., Høiby, Niels
openaire +2 more sources
BMC Microbiology, 2022 Background Proteus mirabilis is an opportunistic pathogen, causing a variety of community-acquired and nosocomial illnesses. It poses a potential threat to patients via the production of β-lactamases, which decrease the efficacy of antimicrobial ...
Mona I. Shaaban +2 more
semanticscholar +1 more source
Infection and Drug Resistance, 2022 Carbapenemases are β-lactamase enzymes that hydrolyze a variety of β-lactams including carbapenem and belong to different Ambler classes (A, B, D). These enzymes can be encoded by plasmid or chromosomal-mediated genes.
Neetu Gupta, K. Angadi, S. Jadhav
semanticscholar +1 more source
European Journal of Clinical Microbiology and Infectious Diseases, 2022 To evaluate the prevalence of multi-carbapenemase-producing Enterobacterales (EB) and the activity of cefiderocol (CFDC), meropenem-vaborbactam (MEV), ceftazidime-avibactam (CZA), and combinations of CZA plus aztreonam (ATM), MEV plus ATM and CFDC plus ...
G. Bianco +6 more
semanticscholar +1 more source
Emerging carbapenemases in Gram-negative aerobes [PDF]
, 2002 Carbapenemases may be defined as β-lactamases that significantly hydrolyze at least imipenem or/and meropenem. Carbapenemases involved in acquired resistance are of Ambler molecular classes A, B, and D.
L. Poirel +3 more
core +1 more source