Clinical Experience with Ceftazidime-Avibactam for the Treatment of Infections due to Multidrug-Resistant Gram-Negative Bacteria Other than Carbapenem-Resistant Enterobacterales [PDF]
Antibiotics, 2020 Experience in real clinical practice with ceftazidime-avibactam for the treatment of serious infections due to gram-negative bacteria (GNB) other than carbapenem-resistant Enterobacterales (CRE) is very ...
Antonio Vena +2 more
exaly +7 more sources
Aztreonam: clinical and pharmacological characteristics at the present stage [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2023 One of the urgent problems of modern health care is the growing resistance of microorganisms to antibiotics, including carbapenems, which until recently were considered as the drugs of choice in the treatment of life-threatening infections.
Popov D.A. +2 more
doaj +1 more source
Evaluation of Xpert Carba-R for detecting carbapenemase-producing organisms in South Africa
African Journal of Laboratory Medicine, 2023 This study evaluated the performance of the Xpert Carba-R assay for detecting the five common carbapenemases in carbapenemase-producing organisms in Johannesburg, South Africa between April 2021 and September 2021.
Sanelisiwe T. Duze +5 more
doaj +1 more source
Application of AMRmap: «from the general to the specific» approach by the example of Klebsiella pneumoniae [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2019 The options for the use of «Plot By» tab in the web platform AMRmap are reviewed in the article. Description of some functionality is supported by the specific examples, and Klebsiella pneumoniae was selected as a study object.
Vinogradova A.G., Kuzmenkov A.Yu.
doaj +1 more source
Journal of Pure and Applied Microbiology, 2023 Global dissemination of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-negative bacteria (GNB) such as carbapenemase-producing Enterobacterales has resulted in reviving colistin as a final therapeutic alternative. Colistin resistance
Amal F. Makled +6 more
doaj +1 more source
Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]
, 2020 Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen +8 more
core +2 more sources
Activity of cefiderocol against high-risk clones of multidrug-resistant Enterobacterales, Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia [PDF]
, 2020 BACKGROUND: Cefiderocol is a novel siderophore cephalosporin, developed for activity against MDR Gram-negative bacilli (MDR-GNB). OBJECTIVES: To assess the in vitro antibacterial activity of cefiderocol against a collection of MDR-GNB clinical ...
Conejo, Mª del Carmen +4 more
core +1 more source
Molecular characterization of extended-spectrum beta-lactamase-producing Enterobacterales isolates collected from blood culture in patients with hematological malignancies [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2018 Objective. The objective of the study was to evaluate the prevalance of genes blaTEM, blaSHV and blaCTX-M among extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales isolates collected from blood culture in patients with hematological ...
Khrulnova S.A. +4 more
doaj +1 more source
Detection of mcr-1-mediated resistance to polymyxins in Enterobacterales using colistin disk chelator application [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2022 Objective. To evaluate the possibility of using the colistin disk chelator application (CDCA) method as simple and available screening tool for detection of mcr-1-mediated resistance to polymyxins in Enterobacterales. Materials and Methods.
Azyzov I.S., Martinovich А.А.
doaj +1 more source
Ceftolozane/tazobactam – the "new player" in a battle against multiresistant pathogens [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2018 Ceftolozane/tazobactam is a new combined antibacterial agent for the treatment of infections caused by gram-negative microorganisms, P. aeruginosa in particular, including strains resistant to other clinically available antimicrobials.
Golub A.V., Kozlov R.S.
doaj +1 more source