The Changing Epidemiology of Carbapenemase-Producing Enterobacterales [PDF]
Rambam Maimonides Medical Journal, 2022 Objective Israeli hospitals were confronted with a major national outbreak of carbapenemase-producing Enterobacterales (CPE) starting in 2006, caused predominantly by monoclonal Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ...
Khetam Hussein +7 more
doaj +3 more sources
Fast genome-based delimitation of Enterobacterales species
PLOS ONE, 2023 Average Nucleotide Identity (ANI) is becoming a standard measure for bacterial species delimitation. However, its calculation can take orders of magnitude longer than similarity estimates based on sampling of short nucleotides, compiled into so-called sketches. These estimates are widely used.
Julie E. Hernández-Salmerón +2 more
openaire +4 more sources
Virulence Factors and Antibiotic Resistance of Enterobacterales
Microorganisms, 2022 In the class Gammaproteobacteria, Enterobacterales are Gram-negative, facultatively anaerobic bacteria [...]
Dobroslava Bujňáková +2 more
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Activity of mecillinam against carbapenem-resistant Enterobacterales
Journal of Antimicrobial Chemotherapy, 2022 Abstract Background Despite the fact that carbapenem-resistant Enterobacterales (CRE) mostly cause urinary tract infections (UTIs), only few studies have focused on the efficacity of mecillinam against these CRE.
Emeraud, Cécile +9 more
openaire +3 more sources
Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump. [PDF]
, 2020 The efflux pumps from the Resistance-Nodulation-Division family, RND, are main contributors to intrinsic antibiotic resistance in Gram-negative bacteria. Among this family, the MdtABC pump is unusual by having two inner membrane components.
Górecki, Kamil, McEvoy, Megan M
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Differences in microbiota between two multilocus lineages of the sugarcane Aphid (Melanaphis sacchari) in the continental United States [PDF]
, 2020 The sugarcane aphid (SCA), Melanaphis Sacchari (Zehntner) (Hemiptera: Aphididae), has been considered an invasive pest of sugarcane in the continental United States since 1977. Then, in 2013, SCA abruptly became a serious pest of U.S.
Antwi, Josephine B. +11 more
core +1 more source
Journal of Pure and Applied Microbiology, 2022 The prevalence of multidrug-resistant gram-negative bacilli has increased worldwide. Critical care areas of most hospitals use carbapenem antibiotics for the empirical treatment of gram-negative bacterial (GNB) infections.
Amisha Piyush Khare +3 more
doaj +1 more source
Journal of Pure and Applied Microbiology, 2023 In recent years, a wide range of clinical infections are being caused by carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa. This is a matter of great concern, as carbapenem-resistant infections have fewer treatment
Gaurav Verma +6 more
doaj +1 more source
Lung penetration, bronchopulmonary pharmacokinetic/pharmacodynamic profile and safety of 3 g of ceftolozane/tazobactam administered to ventilated, critically ill patients with pneumonia [PDF]
, 2020 Objectives: Ceftolozane/tazobactam is approved for hospital-acquired/ventilator-associated bacterial pneumonia at double the dose (i.e. 2 g/1 g) recommended for other indications.
Adedoyin, Adedayo +9 more
core +1 more source
Activity of imipenem/relebactam against Enterobacterales and Pseudomonas aeruginosa in Spain. SMART 2016-2020 [PDF]
, 2023 Objectives. To determine susceptibility to the novel β-lactam/β-lactamase inhibitor combination imipenem/relebactam in clinical isolates recovered from intra-abdominal (IAI), urinary (UTI), respiratory (RTI) and bloodstream (BSI) infections in the SMART (
Calvo, Jorge +14 more
core +1 more source