Results 1 to 10 of about 2,236,849 (269)

Carbapenem resistance in the food supply chain

Journal of Food Protection, 2023
Carbapenems are critically important antibiotic agents because they are considered the “last-resort” antibiotics for treating serious infections. However, resistance to carbapenems is increasing throughout the world and has become an urgent problem. Some
En Huang, Xu Yang, Elizabeth Leighton, Xinhui Li   +3 more
doaj   +6 more sources

Genomic Features Associated with the Degree of Phenotypic Resistance to Carbapenems in Carbapenem-Resistant Klebsiella pneumoniae

mSystems, 2021
Carbapenem-resistant Klebsiella pneumoniae strains cause severe infections that are difficult to treat. The production of carbapenemases such as the K.
Zackery P. Bulman, Fiorella Krapp, Nathan B. Pincus, Eric Wenzler, Katherine R. Murphy, Chao Qi, Egon A. Ozer, Alan R. Hauser   +7 more
doaj   +4 more sources

The synergistic action of reduced membrane permeability and antibiotic sequestration as a novel mechanism for carbapenem resistance in Campylobacter [PDF]

mBio
Carbapenems are last-resort antibiotics against gram-negative pathogens, including multidrug-resistant Campylobacter. However, carbapenem-resistant Campylobacter strains are emerging and have been isolated in patients treated with carbapenems.
Xinggui Chen, Yulian Zhou, Quan Zhou, Min He, Mengyu Zhao, Suchuan Dai, Jinpeng Li, Chengyao Hou, Weilai Tao, Xinyi Yang, Shiying Lan, Xin Yang, Changwei Lei, Anyun Zhang, Hongning Wang, Yizhi Tang   +15 more
doaj   +2 more sources

Reversal of carbapenem-resistance in Shewanella algae by CRISPR/Cas9 genome editing

Journal of Advanced Research, 2019
Antibiotic resistance in pathogens is a growing threat to human health. Of particular concern is resistance to carbapenem, which is an antimicrobial agent listed as critically important by the World Health Organization.
Zong-Yen Wu, Yao-Ting Huang, Wen-Cheng Chao, Shu-Peng Ho, Jan-Fang Cheng, Po-Yu Liu   +5 more
doaj   +3 more sources

Prevalence and molecular epidemiology of carbapenem-resistant Gram-negative bacilli and their resistance determinants in the Eastern Mediterranean Region over the last decade

Journal of Global Antimicrobial Resistance, 2021
: Carbapenem resistance in Enterobacteriaceae, Acinetobacter baumannii and Pseudomonas aeruginosa is increasing worldwide, which has led the World Health Organization (WHO) to list these bacteria in the critical priority pathogens group.
Ahmad Sleiman, Antoine G. Abou Fayad, Hanin Banna, Ghassan M. Matar   +3 more
doaj   +3 more sources

A systematic review and meta-analysis of carbapenem resistance and its possible treatment options with focus on clinical Enterobacteriaceae: Thirty years of development in Pakistan

Heliyon
Background: Carbapenem resistance is epidemic worldwide, these last resort antimicrobials are listed in the WHO ‘watch group’ with higher resistance potential.
Muhammad Umair, Timothy R. Walsh, Mashkoor Mohsin   +2 more
doaj   +3 more sources

The evolutionary mechanism of non-carbapenemase carbapenem-resistant phenotypes in Klebsiella spp

eLife, 2023
Antibiotic resistance is driven by selection, but the degree to which a bacterial strain’s evolutionary history shapes the mechanism and strength of resistance remains an open question.
Natalia C Rosas, Jonathan Wilksch, Jake Barber, Jiahui Li, Yanan Wang, Zhewei Sun, Andrea Rocker, Chaille T Webb, Laura Perlaza-Jiménez, Christopher J Stubenrauch, Vijaykrishna Dhanasekaran, Jiangning Song, George Taiaroa, Mark Davies, Richard A Strugnell, Qiyu Bao, Tieli Zhou, Michael J McDonald, Trevor Lithgow   +18 more
doaj   +1 more source

Detection of carbapenem-resistance genes in bacteria isolated from wastewater in Ontario

FACETS, 2021
Bacterial carbapenem resistance is a major public health concern since these antimicrobials are often the last resort to treat serious human infections.
Ashley L. Cooper, Cassandra Carter, Hana McLeod, Marie Wright, Prithika Sritharan, Sandeep Tamber, Alex Wong, Catherine D. Carrillo, Burton W. Blais   +8 more
doaj   +1 more source

An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife

Frontiers in Veterinary Science, 2023
Carbapenem resistance (CR) is a major global health concern. CR is a growing challenge in clinical settings due to its rapid dissemination and low treatment options.
Flor Y. Ramírez-Castillo, Alma L. Guerrero-Barrera, Francisco J. Avelar-González   +2 more
doaj   +1 more source

A molecular investigation of carbapenem resistant enterobacteriaceae and blakpc, blandm and blaoxa-48 genes in raw milk [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2020
The success of antibiotic treatment has been negatively affected due to developing and spreading antimicrobial resistance all over the world. The present study was carried out to reveal the presence of carbapenem resistant Enterobacteriaceae and blaKPC ...
Serhat AL, Harun HIZLISOY, Nurhan ERTAŞ ONMAZ, Fulden KARADAL, Mukaddes BAREL, Yeliz YILDIRIM, Zafer GÖNÜLALAN   +6 more
doaj   +1 more source