Results 1 to 10 of about 49,830 (257)

First report of phenotypic and genotypic (blaOXA-61) beta-lactam resistance in Campylobacter jejuni from broilers in Indonesia [PDF]

Veterinary World, 2023
Background and Aim: Campylobacter is a zoonotic bacterium that is a major source of foodborne diseases. In humans, most cases of campylobacteriosis are caused by Campylobacter jejuni.
Sheila Marty Yanestria, Mustofa Helmi Effendi, Wiwiek Tyasningsih, Mariyono Mariyono, Emmanuel Nnabuike Ugbo   +4 more
doaj   +2 more sources

Acid-dependent beta-lactam resistance in Klebsiella pneumoniae is mediated by paralogous class B PBPs and the class A PBP, PBP1b [PDF]

mBio
Klebsiella pneumoniae is a leading cause of global deaths due to antibiotic resistance. Of particular concern is the rapid expansion of resistance to beta-lactam antibiotics within K. pneumoniae lineages. The environmental factors that influence pathogen
Sarah Beagle, Petra Anne Levin
doaj   +2 more sources

Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance. [PDF]

Antimicrob Steward Healthc Epidemiol
Wilber E, Smith G, Jacob JT, Rebolledo PA.   +3 more
europepmc   +4 more sources

Pengolahan Air Limbah Betalaktam Menggunakan Reagen Kaporit, PAC, dan Alum Sulfat

Jurnal Serambi Engineering, 2021
Beta lactam  antibiotics are pollutant in water bodies such as lakes and rivers. Beta lactam rings may have a negative impact on living beings  in lakes and rivers. Beta lactam rings also cause resistance or bacterial resistance to antibiotics.
Gede H. Cahyana, Gilang Gumilar, Tri Mulyani   +2 more
doaj   +1 more source

Profile of Enterobacteria Resistant to Beta-Lactams [PDF]

Antibiotics, 2020
A serious emerging problem worldwide is increased antimicrobial resistance. Acquisition of coding genes for evasion methods of antimicrobial drug mechanisms characterizes acquired resistance. This phenomenon has been observed in Enterobacteriaceae family.
Andressa Liberal Santos, Adailton Pereira dos Santos, Célia Regina Malveste Ito, Pedro Henrique Pereira de Queiroz, Juliana Afonso de Almeida, Marcos Antonio Batista de Carvalho Júnior, Camila Zanatta de Oliveira, Melissa Ameloti G. Avelino, Isabela Jubé Wastowski, Giselle Pinheiro Lima Aires Gomes, Adenícia Custódia Silva e Souza, Lara Stefânia Netto de Oliveira Leão Vasconcelos, Mônica de Oliveira Santos, Carla Afonso da Silva, Lilian Carla Carneiro   +14 more
openaire   +3 more sources

Overview of Beta-Lactam Allergy and the Role of the Pharmacist in Management

Allergies, 2021
Unverified beta-lactam allergies are a substantial public health problem, as the majority of patients labeled as beta-lactam allergic do not have clinically significant allergies that may hinder the use beta-lactam therapy when indicated.
Nicole Bradley, Yuman Lee, Dana Weinstein   +2 more
doaj   +1 more source

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

Nature Communications, 2023
There is an arms race between beta-lactam antibiotics development and co-evolving beta-lactamases, which provide resistance by breaking down beta-lactam rings.
Ladan Khodaparast, Laleh Khodaparast, Guiqin Wu, Emiel Michiels, Rodrigo Gallardo, Bert Houben, Teresa Garcia, Matthias De Vleeschouwer, Meine Ramakers, Hannah Wilkinson, Ramon Duran-Romaña, Johan Van Eldere, Frederic Rousseau, Joost Schymkowitz   +13 more
doaj   +1 more source

Resistance to beta-lactams in Mycobacterium fortuitum [PDF]

Antimicrobial Agents and Chemotherapy, 1992
It is widely assumed that the high level of intrinsic resistance to beta-lactam antibiotics exhibited by mycobacteria results from the combination of factors including permeability to the drugs, beta-lactamase production, and affinity for penicillin-binding proteins (PBPs).
L, Fattorini, G, Orefici, S H, Jin, G, Scardaci, G, Amicosante, N, Franceschini, I, Chopra   +6 more
openaire   +2 more sources

Why We May Need Higher Doses of Beta-Lactam Antibiotics: Introducing the ‘Maximum Tolerable Dose’

Antibiotics, 2022
The surge in antimicrobial resistance and the limited availability of new antimicrobial drugs has fueled the interest in optimizing antibiotic dosing. An ideal dosing regimen leads to maximal bacterial cell kill, whilst minimizing the risk of toxicity or
Sofie A. M. Dhaese, Eric A. Hoste, Jan J. De Waele   +2 more
doaj   +1 more source

Infectious disease: how to manage Gram-positive and Gram-negative pathogen conundrums with dual beta-lactam therapy

Drugs in Context, 2022
Antimicrobial resistance is a global public health threat due to its associated increase in mortality, and the most appropriate treatment algorithms for resistant and persistent Gram-positive and Gram-negative infections have yet to be elucidated. Whilst
Alireza FakhriRavari, Brenda Simiyu, Taylor Morrisette, Yewande Dayo, Jacinda C Abdul-Mutakabbir   +4 more
doaj   +1 more source