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Antimicrobial resistance due to the continuous selective pressure from widespread use of antimicrobials in humans, animals and agriculture has been a growing problem for last decades. KPC beta-lactamases hydrolyzed beta-lactams of all classes. Especially,
Piotr Wieczorek +6 more
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Efflux pump, the masked side of beta-lactam resistance in Klebsiella pneumoniae clinical isolates. [PDF]
BACKGROUND: Beta-lactamase production and porin decrease are the well-recognized mechanisms of acquired beta-lactam resistance in Klebsiella pneumoniae isolates. However, such mechanisms proved to be absent in K.
Jean-Marie Pages +6 more
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Methicillin-resistant Staphylococcus aureus (MRSA) is a rapidly emerging bacteria causing infection, which has developed resistance to most of the beta-lactam antibiotics because of newly acquired low-affinity penicillin binding protein (PBP2a), which ...
Shrikant Pawar, Xiangyu Yao, ChungDar Lu
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Background: The objective was to identify associations between beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) targets and Gram-negative bacteria resistance emergence in patients. Methods: Retrospective data were collected between 2016 to 2019 at the
Nicole F. Maranchick +4 more
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Beta–Lactam Drug Resistance Pattern In Staphylococcus Aureus Isolates: A Review
Methicillin Resistance Staphylococcus aureus (MRSA) is a serious human disease also considered as a chronological developing zoonotic pathogen of common health and in term of veterinary concern.
Kovan Dilawer Issa +1 more
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Objective: Investigate beta-lactam resistance in order to identify the associated factors, the main beta-lactam resistant microorganisms and their complications. Theoretical Framework: Beta-lactam resistance is a worldwide health problem, consisting of the inability to respond to the action of antibiotics.
Kerly Monserrath Pinos Larrea +5 more
openaire +1 more source
beta-Lactamases and beta-lactam resistance in Escherichia coli [PDF]
Escherichia coli strains determining 17 different plasmid-determined beta-lactamases were tested for resistance to new broad-spectrum beta-lactam antibiotics. Several beta-lactamases demonstrated enhanced resistance to cefamandole but only low-level resistance to other agents. High production of cloned E.
G A, Jacoby, L, Sutton
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AIM: To determine in vitro susceptibilities of H. influenzae strains and to reveal the beta-lactam resistance mechanisms involved in those resistant to beta-lactams in our center. METHODS: Antibiotic susceptibilities of 122 H. influenzae isolated in 2022
Meltem Sarı Küçükerol +2 more
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The Relationship between Antimicrobial Use and Antimicrobial Resistance in Europe
In Europe, antimicrobial resistance has been monitored since 1998 by the European Antimicrobial Resistance Surveillance System (EARSS). We examined the relationship between penicillin nonsusceptibility of invasive isolates of Streptococcus pneumoniae (an
Stef L.A.M. Bronzwaer +8 more
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Beta‐lactam antibiotics: from antibiosis to resistance and bacteriology [PDF]
Kong K‐F, Schneper L, Mathee K. Beta‐lactam antibiotics: from antibiosis to resistance and bacteriology. APMIS 2010; 118: 1–36.This review focuses on the era of antibiosis that led to a better understanding of bacterial morphology, in particular the cell wall component peptidoglycan. This is an effort to take readers on a tour de force from the concept
Kong, Kok-Fai +2 more
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