Results 11 to 20 of about 49,413 (255)

Resistance to beta-lactam antibiotics in Streptococcus faecium [PDF]

Antimicrobial Agents and Chemotherapy, 1982
Clinical isolates of Streptococcus faecium are characteristically resistant to beta-lactam antibiotics. Two strains, selected for hypersusceptibility to penicillin, were derived from normally resistant isolates treated with novobiocin. These strains were also found to be hypersusceptible to other beta-lactams.
G M, Eliopoulos, C, Wennersten, R C, Moellering   +2 more
openaire   +2 more sources

PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance

Microorganisms, 2018
β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Thaina M. da Costa, Carolina R. de Oliveira, Henry F. Chambers, Som S. Chatterjee   +3 more
doaj   +1 more source

Historical Review of the Penicillin and Related Compounds (β – Lactams)

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
In spite of  the old age of beta lactam, they continue to provide good health and preventing human diseases by virtue of  industrial production and discoveries of small new beta-lactam group of secondary metabolite.
Luma Salman Abd
doaj   +1 more source

Comprehensive identification of single nucleotide polymorphisms associated with beta-lactam resistance within pneumococcal mosaic genes. [PDF]

PLoS Genetics, 2014
Traditional genetic association studies are very difficult in bacteria, as the generally limited recombination leads to large linked haplotype blocks, confounding the identification of causative variants.
Claire Chewapreecha, Pekka Marttinen, Nicholas J Croucher, Susannah J Salter, Simon R Harris, Alison E Mather, William P Hanage, David Goldblatt, Francois H Nosten, Claudia Turner, Paul Turner, Stephen D Bentley, Julian Parkhill   +12 more
doaj   +1 more source

Molecular characterization of ESBL-producing Shigella sonnei isolates from patients with bacilliary dysentery in Lebanon

Journal of Infection in Developing Countries, 2009
Background: Emergence of extended-spectrum -lactamases (ESBLs) in Shigella species imparting resistance to third-generation cephalosporins is a growing concern worldwide. The aim of this study is to molecularly characterize the newly emerging beta-lactam
Ahmad H. Sabra, George F. Araj, Mireille M. Kattar, Roland Y. Abi-Rached, Marie-Therese Khairallah, John D. Glena, Ghassan M. Matar   +6 more
doaj   +1 more source

Beta-lactam resistance response triggered by inactivation of a nonessential penicillin-binding protein.

PLoS Pathogens, 2009
It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for beta-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance.
Bartolomé Moya, Andreas Dötsch, Carlos Juan, Jesús Blázquez, Laura Zamorano, Susanne Haussler, Antonio Oliver   +6 more
doaj   +1 more source

Mechanism of resistance to beta-lactam antibiotics

BULLETIN of the L.N. Gumilyov Eurasian National University. BIOSCIENCE Series, 2023
Acinetobacter baumannii is the most commonly associated human pathogen with infections in the genus. This opportunistic pathogen causes quite serious infections, especially in fond patients, and has the ability to quickly develop resistance to new antibiotics. In the recent past, carbapenems, a.
R. Khalilov, M. Mammadova, Sh. Abdullayeva   +2 more
openaire   +1 more source

Quarter-wise proportion and beta-lactam resistance rate of bovine mastitis associated- Staphylococcus aureus among infectious episodes in Ethiopia: Systematic review and meta-Analysis

Heliyon, 2023
Background: Bovine mastitis, a condition with multifactorial etiology, imposes a significant economic burden on the dairy sector in Ethiopia, with Staphylococcus aureus (S. aureus) being one of the leading etiologic agents.
Melkie Dagnaw Fenta, Firdyawukal Abuhay Tafere, Atsede Solomon Mebratu, Birhan Anagaw Malede   +3 more
doaj   +1 more source

Prevalence of Antibiotic Resistance Genes in Multidrug-Resistant Enterobacteriaceae on Portuguese Livestock Manure

Antibiotics, 2019
The exposure of both crop fields and humans to antibiotic-resistant bacteria in animal excreta is an emergent concern of the One Health initiative.
Paula Amador, Ruben Fernandes, Cristina Prudêncio, Isabel Duarte   +3 more
doaj   +1 more source

Efflux pump, the masked side of beta-lactam resistance in Klebsiella pneumoniae clinical isolates. [PDF]

PLoS ONE, 2009
BACKGROUND: Beta-lactamase production and porin decrease are the well-recognized mechanisms of acquired beta-lactam resistance in Klebsiella pneumoniae isolates. However, such mechanisms proved to be absent in K.
Jean-Marie Pages, Jean-Philippe Lavigne, Véronique Leflon-Guibout, Estelle Marcon, Frédéric Bert, Latifa Noussair, Marie-Hélène Nicolas-Chanoine   +6 more
doaj   +1 more source