Quarter-wise proportion and beta-lactam resistance rate of bovine mastitis associated- Staphylococcus aureus among infectious episodes in Ethiopia: Systematic review and meta-Analysis [PDF]
Heliyon, 2023 Background: Bovine mastitis, a condition with multifactorial etiology, imposes a significant economic burden on the dairy sector in Ethiopia, with Staphylococcus aureus (S. aureus) being one of the leading etiologic agents.
Melkie Dagnaw Fenta +3 more
doaj +2 more sources
Acid-dependent beta-lactam resistance in Klebsiella pneumoniae is mediated by paralogous class B PBPs and the class A PBP, PBP1b [PDF]
mBioKlebsiella pneumoniae is a leading cause of global deaths due to antibiotic resistance. Of particular concern is the rapid expansion of resistance to beta-lactam antibiotics within K. pneumoniae lineages. The environmental factors that influence pathogen
Sarah Beagle, Petra Anne Levin
doaj +2 more sources
In Vitro Selection of High-Level Beta-Lactam Resistance in Methicillin-Susceptible Staphylococcus aureus. [PDF]
Antibiotics (Basel), 2021 Selective pressure of beta-lactams is thought to be responsible for mutation selection in methicillin-susceptible Staphylococcus aureus (MSSA). We used next-generation sequencing to compare the genomes of beta-lactamase-positive (SA0707) and -negative ...
Gostev V +6 more
europepmc +2 more sources
PLoS Pathogens, 2009 It has long been recognized that the modification of penicillin-binding proteins (PBPs) to reduce their affinity for beta-lactams is an important mechanism (target modification) by which Gram-positive cocci acquire antibiotic resistance.
Bartolomé Moya +6 more
doaj +2 more sources
Modelling impacts of paediatric amoxicillin shortage management on pneumococcal resistance and invasive disease in Europe [PDF]
Nature CommunicationsAntibiotic shortages are increasing worldwide. Their impact on individual health and bacterial ecology is unknown, but it could be significant, and there is a lack of epidemiological evidence. Here, we assess the impact of beta-lactam shortage management
Aurélie Maurin +6 more
doaj +2 more sources
Beta-lactam resistance in Campylobacter [PDF]
, 2011 Resistance to β-lactam antibiotics in Campylobacter is often associated with the production of a β-lactamase; to date the genomically encoded bla\(_{OXA-61}\) and the closely related cj0299 are the only described β-lactamase genes of Campylobacter ...
Stones, Leanne
core +7 more sources
Penicillin allergy documentation in the UAE: 10-year trends and stewardship implications [PDF]
Frontiers in MedicineIntroductionPenicillin allergy labels are frequently documented in electronic medical records (EMRs), although most patients are not truly allergic upon formal evaluation.
Aaesha Alteneiji +3 more
doaj +2 more sources
Proportion of carbapenem-resistant Enterobacterales with readily detectable beta-lactam resistance [PDF]
Antimicrobial Stewardship & Healthcare EpidemiologyEli Wilber +3 more
openaire +4 more sources
Characterization of Beta-Lactam Resistome of Escherichia coli Causing Nosocomial Infections
Antibiotics, 2023 Nosocomial infections caused by Escherichia coli pose significant therapeutic challenges due to the high expression of genes encoding antimicrobial drug resistance.
Rosalino Vázquez-López +8 more
doaj +1 more source
PBP4: A New Perspective on Staphylococcus aureus β-Lactam Resistance
Microorganisms, 2018 β-lactam antibiotics are excellent drugs for treatment of staphylococcal infections, due to their superior efficacy and safety compared to other drugs.
Thaina M. da Costa +3 more
doaj +1 more source