Results 31 to 40 of about 2,940,166 (197)

Efflux pump, the masked side of beta-lactam resistance in Klebsiella pneumoniae clinical isolates. [PDF]

PLoS ONE, 2009
BACKGROUND: Beta-lactamase production and porin decrease are the well-recognized mechanisms of acquired beta-lactam resistance in Klebsiella pneumoniae isolates. However, such mechanisms proved to be absent in K.
Jean-Marie Pages, Jean-Philippe Lavigne, Véronique Leflon-Guibout, Estelle Marcon, Frédéric Bert, Latifa Noussair, Marie-Hélène Nicolas-Chanoine   +6 more
doaj   +1 more source

Transcriptomic data for analyzing global gene expression patterns in Methicillin-resistance Staphylococcus aureus in response to spermine and oxacillin stress

Data in Brief, 2018
Methicillin-resistant Staphylococcus aureus (MRSA) is a rapidly emerging bacteria causing infection, which has developed resistance to most of the beta-lactam antibiotics because of newly acquired low-affinity penicillin binding protein (PBP2a), which ...
Shrikant Pawar, Xiangyu Yao, ChungDar Lu
doaj   +1 more source

Impact of Beta-Lactam Target Attainment on Resistance Development in Patients with Gram-Negative Infections

Antibiotics, 2023
Background: The objective was to identify associations between beta-lactam pharmacokinetic/pharmacodynamic (PK/PD) targets and Gram-negative bacteria resistance emergence in patients. Methods: Retrospective data were collected between 2016 to 2019 at the
Nicole F. Maranchick, Jessica Webber, Mohammad H. Alshaer, Timothy W. Felton, Charles A. Peloquin   +4 more
doaj   +1 more source

beta-Lactamases and beta-lactam resistance in Escherichia coli [PDF]

Antimicrobial Agents and Chemotherapy, 1985
Escherichia coli strains determining 17 different plasmid-determined beta-lactamases were tested for resistance to new broad-spectrum beta-lactam antibiotics. Several beta-lactamases demonstrated enhanced resistance to cefamandole but only low-level resistance to other agents. High production of cloned E.
G A, Jacoby, L, Sutton
openaire   +2 more sources

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
William Gaze, Gaze, William H., Hawkey, Peter, Peter Hawkey, Hawkey, P. M., O'Neill, Colette, O'Neill, C, Colette O'Neill, Elizabeth Wellington, Gaze, W, Wellington, E, Wellington, Elizabeth, Wellington, E. M. H., Gaze, William   +13 more
core   +1 more source

Beta-Lactam Resistance

Revista de Gestão Social e Ambiental
Objective: Investigate beta-lactam resistance in order to identify the associated factors, the main beta-lactam resistant microorganisms and their complications.   Theoretical Framework: Beta-lactam resistance is a worldwide health problem, consisting of the inability to respond to the action of antibiotics.
Kerly Monserrath Pinos Larrea, Jacinto Eugenio Pérez Ramírez, Marco Vinicio Urgilés Rivas, Gustavo Adolfo Espinoza Palomeque, Juan Sebastián Urgilés Beltrán, Félix Miguel Sacoto Maldonado   +5 more
openaire   +1 more source

Beta‐lactam antibiotics: from antibiosis to resistance and bacteriology [PDF]

APMIS, 2009
Kong K‐F, Schneper L, Mathee K. Beta‐lactam antibiotics: from antibiosis to resistance and bacteriology. APMIS 2010; 118: 1–36.This review focuses on the era of antibiosis that led to a better understanding of bacterial morphology, in particular the cell wall component peptidoglycan. This is an effort to take readers on a tour de force from the concept
Kong, Kok-Fai, Schneper, Lisa, Mathee, Kalai   +2 more
openaire   +2 more sources

Surfactant-free purification of membrane protein complexes from bacteria: application to the staphylococcal penicillin-binding protein complex PBP2/PBP2a. [PDF]

, 2014
Surfactant-mediated removal of proteins from biomembranes invariably results in partial or complete loss of function and disassembly of multi-protein complexes. We determined the capacity of styrene-co-maleic acid (SMA) co-polymer to remove components of
Taylor, Peter W, Paulin, S, Roper, David I, Garcia-Lara, J, Roper, DI, Taylor, PW, Galley, Nicola F., Paulin, Sarah, Rosado, H, Foster, SJ, Taylor, Peter W., Dafforn, TR, Dafforn, Tim, Dafforn, Timothy R, Galley, Nicola F, Jamshad, Mohammed, Rosado, Helena, Foster, Simon J, Garcia-Lara, Jorge, Jamshad, M, Galley, NF, Foster, Simon J., Roper, David I.   +22 more
core   +1 more source

Beta–Lactam Drug Resistance Pattern In Staphylococcus Aureus Isolates: A Review

Eurasian Journal of Science and Engineering, 2023
Methicillin Resistance Staphylococcus aureus (MRSA) is a serious human disease also considered as a chronological developing zoonotic pathogen of common health and in term of veterinary concern.
Kovan Dilawer Issa, Mohammed Dlshad Muhsin   +1 more
doaj   +1 more source

ftsI mutations versus beta-lactamase (blaTEM) production in beta-lactam resistance of Haemophilus influenzae: results from an university hospital in Istanbul

Journal of Global Antimicrobial Resistance
AIM: To determine in vitro susceptibilities of H. influenzae strains and to reveal the beta-lactam resistance mechanisms involved in those resistant to beta-lactams in our center. METHODS: Antibiotic susceptibilities of 122 H. influenzae isolated in 2022
Meltem Sarı Küçükerol, Burak Aksu, Ufuk Hasdemir   +2 more
doaj   +1 more source