Results 41 to 50 of about 2,377,546 (217)

Sustained pediatric antimicrobial stewardship program with consultation to infectious diseases reduced carbapenem resistance and infection-related mortality

open access: yesInternational Journal of Infectious Diseases, 2017
Objective: The impact of pediatric antimicrobial stewardship programs (ASP) on antimicrobial resistance (AMR) remains largely unknown. This study aimed to evaluate the AMR for carbapenem of Gram-negative bacilli (GNB) and carbapenem use with infectious ...
Yuho Horikoshi   +9 more
doaj   +1 more source

Characterisation of carbapenem-resistant Gram-negative organisms from clinical specimens in Yola, Nigeria

open access: yesJournal of Global Antimicrobial Resistance, 2020
Objectives: This study aimed to identify carbapenem-resistant Gram-negative bacteria from clinical specimens of patients in Yola, Nigeria. Methods: Routine clinical specimens were screened for the presence of carbapenem-resistant Gram-negative bacteria ...
Shuwaram A. Shettima   +3 more
doaj   +1 more source

Carbapenemase-producing Aeromonas species isolated from the urban-impacted Akaki river in Ethiopia

open access: yesJournal of Water and Health, 2022
Carbapenemase-producing Aeromonas species are an emerging health threat. This study aimed to determine carbapenemase-mediated resistance among Aeromonas isolates from the Akaki river, Ethiopia during the dry and wet seasons in 2019–2020.
Berhanu Yitayew   +6 more
doaj   +1 more source

Carbapenem-resistant genes primer sets.

open access: yes, 2023
BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) and Extended-spectrum beta-lactamase (ESBL) production among Gram-negative Enterobacteriaceae is an increasing global challenge due to the high morbidity and mortality associated with their ...
Frank Twum Aboagye (17304867)   +3 more
core   +1 more source

Global prevalence of carbapenem resistance in neutropenic patients and association with mortality and carbapenem use: systematic review and meta-analysis [PDF]

open access: yes, 2016
Background: Carbapenem-resistant Gram-negative bacteria are recognized as a cause of difficult-to-treat infections associated with high mortality. Objectives: To perform a systematic review of currently available data on distribution, characteristics and
Peri, Anna Maria   +20 more
core   +1 more source

Beyond Nature's Blueprint: Macrocyclic Peptides Containing Unnatural Amino Acids in Therapeutic Development

open access: yesAngewandte Chemie, EarlyView.
Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma   +5 more
wiley   +2 more sources

Antimicrobial resistance surveillance in Europe 2013: Annual Report of the European Antimicrobial Resistance Surveillance Network (EARS-Net) [PDF]

open access: yes, 2014
Portugal - EARS-Net Management Team & National representatives of EARS-Net (Manuela Caniça, José Artur Paiva, Vera Manageiro, Eugénia Ferreira)The results presented in this report are based on antimicrobial resistance data from invasive isolates reported
European Antimicrobial Resistance Surveillance Network (EARS-Net)
core   +2 more sources

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

open access: yesAngewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray   +4 more
wiley   +2 more sources

Aminoglycoside-modifying Enzymes in Carbapenem-resistant Pseudomonas aeruginosa Clinical Isolates

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2022
Introduction: Aminoglycosides are the drug of choice for the treatment of Pseudomonas aeruginosa infections. Aminoglycoside resistance in P. aeruginosa often occurred via acquired aminoglycoside-modifying enzymes (AMEs).
Yeliz TANRIVERDİ ÇAYCI   +6 more
doaj   +1 more source

Molecular characteristics and antimicrobial resistance profiles of Carbapenem-Resistant Klebsiella pneumoniae isolates at a tertiary hospital in Nanning, China

open access: yesBMC Microbiology, 2023
Purpose Carbapenem resistant Klebsiella pneumoniae is associated with nosocomial infections and can cause high mortality, which poses great threat to human health.
Xianzhen Wei   +5 more
doaj   +1 more source

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