Importance of site of infection and antibiotic selection in the treatment of carbapenem-resistant Pseudomonas aeruginosa sepsis [PDF]
In a retrospective analysis of 215 patients with carbapenem-resistant Pseudomonas aeruginosa sepsis, we observed a significantly higher risk of mortality associated with respiratory tract infection (risk ratio [RR], 1.20; 95 ...
Britt, Nicholas S +6 more
core +2 more sources
A systematic review: the current status of carbapenem resistance in East Africa
Objective In this systematic review, we present the molecular epidemiology and knowledge gaps of the carbapenem resistance in East Africa as well as the future probable research interventions that can be used to address the emergence of carbapenem ...
Kenneth Ssekatawa +3 more
doaj +1 more source
We report that carbapenem resistance developed in an extensively drug-resistant Salmonella enterica serovar Agona strain during antimicrobial therapy and in an AmpC β-lactamase-producing S. Infantis strain.
Ping-Chun Hsu +6 more
doaj +1 more source
Severe bloodstream infection due to KPC-producer e coli in a renal transplant recipient treated with the double-carbapenem regimen and analysis of in vitro synergy testing a case report [PDF]
Transplant recipients are at high risk of infections caused by multidrug resistant microorganisms. Due to the limited thera- peutic options, innovative antimicrobial combinations against carbape- nem-resistant Enterobacteriaceae causing severe infections
CIPOLLA, ALESSIA +11 more
core +1 more source
Objectives: This study aimed to identify carbapenem-resistant Gram-negative bacteria from clinical specimens of patients in Yola, Nigeria. Methods: Routine clinical specimens were screened for the presence of carbapenem-resistant Gram-negative bacteria ...
Shuwaram A. Shettima +3 more
doaj +1 more source
Carbapenemase-producing Aeromonas species isolated from the urban-impacted Akaki river in Ethiopia
Carbapenemase-producing Aeromonas species are an emerging health threat. This study aimed to determine carbapenemase-mediated resistance among Aeromonas isolates from the Akaki river, Ethiopia during the dry and wet seasons in 2019–2020.
Berhanu Yitayew +6 more
doaj +1 more source
Objective: The impact of pediatric antimicrobial stewardship programs (ASP) on antimicrobial resistance (AMR) remains largely unknown. This study aimed to evaluate the AMR for carbapenem of Gram-negative bacilli (GNB) and carbapenem use with infectious ...
Yuho Horikoshi +9 more
doaj +1 more source
Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC +6 more
core +1 more source
Aminoglycoside-modifying Enzymes in Carbapenem-resistant Pseudomonas aeruginosa Clinical Isolates
Introduction: Aminoglycosides are the drug of choice for the treatment of Pseudomonas aeruginosa infections. Aminoglycoside resistance in P. aeruginosa often occurred via acquired aminoglycoside-modifying enzymes (AMEs).
Yeliz TANRIVERDİ ÇAYCI +6 more
doaj +1 more source
The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]
Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé +95 more
core +1 more source

