Results 11 to 20 of about 78,922 (310)
Reversal of carbapenem-resistance in Shewanella algae by CRISPR/Cas9 genome editing
Journal of Advanced Research, 2019 Antibiotic resistance in pathogens is a growing threat to human health. Of particular concern is resistance to carbapenem, which is an antimicrobial agent listed as critically important by the World Health Organization.
Zong-Yen Wu +5 more
doaj +3 more sources
Mechanisms of Action of Carbapenem Resistance
Antibiotics, 2022 Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections caused by the most resistant bacteria. They belong to the category of β-lactams that include the penicillins, cephalosporins, monobactams and carbapenems. This class of antimicrobials has a broader spectrum of activity than most other beta-lactams antibiotics ...
Aurilio, Caterina +8 more
openaire +5 more sources
A molecular investigation of carbapenem resistant enterobacteriaceae and blakpc, blandm and blaoxa-48 genes in raw milk [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2020 The success of antibiotic treatment has been negatively affected due to developing and spreading antimicrobial resistance all over the world. The present study was carried out to reveal the presence of carbapenem resistant Enterobacteriaceae and blaKPC ...
Serhat AL +6 more
doaj +1 more source
Antimicrobial Resistance in Carbapenem resistance Pseudomonas [PDF]
Pakistan Journal of Medical and Health Sciences, 2021 Aim: To figure out the antimicrobial sensitivity effect of multidrug resistant Pseudomonas aeruginosa obtained from several type of clinical specimens. Study setting: Department of Microbiology and Resource laboratory, University of Health Sciences Lahore.
Sonia Tahir +2 more
openaire +1 more source
Frontiers in Microbiology, 2021 Resistance to last resort drugs such as carbapenem and colistin is a serious global health threat. This study investigated carbapenem and colistin resistance in 583 non-duplicate Enterobacteriaceae isolates utilizing phenotypic methods and whole genome ...
Emmanuel O. Ngbede +17 more
doaj +1 more source
Frontiers in Microbiology, 2022 Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han +10 more
doaj +1 more source
Differential DNA accessibility to polymerase enables 30-minute phenotypic β-lactam antibiotic susceptibility testing of carbapenem-resistant Enterobacteriaceae [PDF]
, 2020 The rise in carbapenem-resistant Enterobacteriaceae (CRE) infections has created a global health emergency, underlining the critical need to develop faster diagnostics to treat swiftly and correctly.
Garner, Omai B. +5 more
core +1 more source
Antibiotics, 2023 The emergence of carbapenem-resistant Klebsiella pneumoniae poses a significant threat to public health. In this study, we aimed to investigate the distribution and genetic diversity of plasmids carrying beta-lactamase resistance determinants in a ...
Chien-Hao Tseng +6 more
doaj +1 more source
Carbapenem Resistance In Enterobacteriaceae [PDF]
Sohag Medical Journal, 2020 Carbapenem resistance is now a public health concern worldwide. Carbapenem is considered the last resort antimicrobial drug used for treatment of hospital care associated infection and community acquired infection that resistant to all other β-lactam drugs. There are a different mechanisms by which bacteria become resistant to carbapenem drug including
Radwa Farag +3 more
openaire +1 more source
Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]
, 2017 In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De +2 more
core +1 more source