Results 61 to 70 of about 2,236,849 (269)

First literature review of carbapenem-resistant Providencia

New Microbes and New Infections, 2018
Providencia species are Gram-negative bacteria that belong to the Enterobacteriaceae family. They have intrinsic resistance to colistin and tigecycline, which makes treatment of the multidrug-resistant strains of Providencia challenging.
M. Abdallah, A. Balshi
doaj   +1 more source

First genomic insights into carbapenem-resistant Klebsiella pneumoniae from Malaysia

Journal of Global Antimicrobial Resistance, 2020
Objectives: Despite the increasing reports of carbapenem-resistant Enterobacteriaceae in Malaysia, genomic resources for carbapenem-resistant clinical strains of Klebsiella pneumoniae (K. pneumoniae) remain unavailable.
Han Ming Gan, Wilhelm Wei Han Eng, Amreeta Dhanoa   +2 more
doaj   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, EarlyView.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

BlaOXA-48 Genotypic Detection of Carbapenem Resistance in Isolates of Pseudomonas Aeruginosa

Journal of Bahria University Medical and Dental College, 2021
Objective: To determine the prevalence of carbapenem resistance in strains of Pseudomonas aeruginosa at a molecular level by detecting OXA-48 gene which transcribe for resistance to the antibiotic carbapenem among indoor patients of a tertiary care ...
Shaista Bakhat, Yasmeen Taj, Faisal Hanif, Saman Nadeem   +3 more
doaj   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

Deaths Attributable to Carbapenem-Resistant Enterobacteriaceae Infections

Emerging Infectious Diseases, 2014
We evaluated the number of deaths attributable to carbapenem-resistant Enterobacteriaceae by using studies from around the world published before April 9, 2012.
Matthew E. Falagas, Giannoula S. Tansarli, Drosos E. Karageorgopoulos, Konstantinos Z. Vardakas   +3 more
doaj   +1 more source

Disease‐Stage Synchronized Nanozyme Therapy for Polymicrobial Sepsis through Adaptive Catalytic and Immune Reprogramming

Advanced Science, EarlyView.
A disease‐stage synchronized nanozyme platform is developed to treat polymicrobial sepsis by adapting its functions to changing infection environments. The system eliminates multidrug‐resistant bacteria during early infection while reducing inflammation and restoring immune balance during recovery, providing an integrated strategy for infection control
Anlai Zou, Xiaoxue Zhu, Runhan Zhu, Chengchu Xue, Qinyu Zhang, Mengke Li, Ting Yu, Yuzhen Gao, Zhi Ruan, Ying Fu, Yunlei Xianyu, Jun Zhang   +11 more
wiley   +1 more source

Molecular insights of Carbapenem resistance Klebsiella pneumoniae isolates with focus on multidrug resistance from clinical samples

Journal of Infection and Public Health, 2021
Background: Carbapenem are the last-line antibiotic, defence against Gram-negative extended spectrum ß-lactamases producers (ESBLs). Carbapenem resistance Enterobacteriaceae especially Carbapenem resistant-Klebsiella pneumoniae (CR-KP) is recognized as ...
Sureka Indrajith, Asish Kumar Mukhopadhyay, Goutam Chowdhury, Dunia A. Al Farraj, Roua M. Alkufeidy, Sivakumar Natesan, Velmurugan Meghanathan, Selvakumar Gopal, Saravanan Muthupandian   +8 more
doaj   +1 more source

Carbapenem-resistant bacteria in the environment

Arhiv za higijenu rada i toksikologiju
Abstract Carbapenem-resistant bacteria (CRB) pose a significant threat to public health due to their resistance to last-resort antibiotics. Even though they are widely studied in clinical settings, much less is known about their presence in environmental compartments with multiple pathways contributing to their ...
Dadić, Blanka, Hrenović, Jasna, Ivanković, Tomislav   +2 more
openaire   +4 more sources

Molecular Identification of Carbapenem Resistance Acinetobacter baumannii causing Ventilator-Associated Pneumonia Isolated from Intensive Care Unit of Tertiary Care Hospital [PDF]

Ventilator-associated pneumonia (VAP) is a serious complication in critically ill patients, significantly increasing morbidity and mortality. One concerning organism behind VAP is Acinetobacter baumannii, a multidrug-resistant bacterium has ability to ...
Aruna Vyas, Vijeta Sharma, Rajni Sharma
core   +1 more source