Results 71 to 80 of about 56,937 (260)

A preliminary exploration on the mechanism of the carbapenem-resistance transformation of Serratia marcescens in vivo

open access: yesBMC Genomics
Background The infection of carbapenem-resistant organisms was a huge threat to human health due to their global spread. Dealing with a carbapenem-resistant Serratia marcescens (CRSM) infection poses a significant challenge in clinical settings.
Qian Xu   +4 more
doaj   +1 more source

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

open access: yesInterdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang   +10 more
wiley   +1 more source

Environmental Contamination by Carbapenem-Resistant Enterobacteriaceae [PDF]

open access: yesJournal of Clinical Microbiology, 2013
ABSTRACT In the last decade, the global emergence of carbapenem resistance in Enterobacteriaceae has posed great concern to public health. Data concerning the role of environmental contamination in the dissemination of carbapenem-resistant Enterobacteriaceae (CRE) are currently ...
Lerner, A.   +5 more
openaire   +2 more sources

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam   +2 more
wiley   +1 more source

Dynamic regression forecasting of carbapenem-resistant Klebsiella spp. based on carbapenem consumption with observed data from 2020 to 2023 and projections up to 2029 in a tertiary hospital in Alexandria, Egypt

open access: yesBMC Infectious Diseases
Background Carbapenem-resistant Klebsiella spp. is a major global health threat. Overuse of carbapenem in healthcare settings, particularly ICUs, has driven the rise of these resistant bacteria. This study aimed to apply dynamic regression forecasting to
Ehab Elmongui   +3 more
doaj   +1 more source

Hospitalized Pets as a Source of Carbapenem-Resistance [PDF]

open access: yesFrontiers in Microbiology, 2018
The massive and irrational use of antibiotics in livestock productions has fostered the occurrence and spread of resistance to "old class antimicrobials." To cope with that phenomenon, some regulations have been already enforced in the member states of the European Union. However, a role of livestock animals in the relatively recent alerts on the rapid
Fabio Gentilini   +12 more
openaire   +4 more sources

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

open access: yesJournal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira   +3 more
wiley   +1 more source

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12

open access: yes, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Wang, X   +11 more
core   +1 more source

Prevalence of carbapenem-resistant Acinetobacter baumannii from 2005 to 2016 in Switzerland [PDF]

open access: yes, 2018
Background : We describe the prevalence of invasive carbapenem-resistant Acinetobacter spp. isolated from 2005 to 2016 in different regions of Switzerland.Methods: Using the Swiss Antibiotic Resistance Centre (anresis) database that includes data from
A. Kronenberg   +5 more
core   +1 more source

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