Results 71 to 80 of about 1,076,076 (217)

The One‐Step Synthesis of Biologically Active Isochromans from Lignin‐Derived Aromatic Monomers in Tunable Deep Eutectic Solvents

open access: yesChemistry – A European Journal, EarlyView.
A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi   +6 more
wiley   +1 more source

Emergence and characterization of new OXA-181 variants in France: OXA-1181, OXA-1201, OXA-1205, OXA-1207, and OXA-1226

open access: yesMicrobiology Spectrum
Since 2022, the diversity of OXA-48 variants has increased in France. We analyzed the dissemination of five recent variants (OXA-1181, OXA-1201, OXA-1205, OXA-1207, and OXA-1226) mostly identified on plasmids in high-risk Escherichia coli clones.
Léa Bientz   +5 more
doaj   +1 more source

Susceptibility of Clinical Enterobacterales Isolates With Common and Rare Carbapenemases to Mecillinam

open access: yesFrontiers in Microbiology, 2021
Purpose: To investigate the susceptibility of carbapenemase-producing Enterobacterales (CPE) to mecillinam based on the recently updated European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints for uncomplicated Urinary Tract ...
Frieder Fuchs   +6 more
doaj   +1 more source

Phenotypic and genotypic characteristics of OXA-48-producing K. pneumoniae isolates.

open access: yes, 2016
Phenotypic and genotypic characteristics of OXA-48-producing K. pneumoniae isolates.
Yanning Ma (3143427)   +6 more
core   +1 more source

Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy

open access: yesChemistry – A European Journal, EarlyView.
Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez   +3 more
wiley   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

open access: yesChemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis   +2 more
wiley   +1 more source

Molecular epidemiology and resistance patterns of blaOXA-48 Klebsiella pneumoniae and Escherichia coli: A nationwide multicenter study in Taiwan

open access: yesJournal of Microbiology, Immunology and Infection, 2021
Background: We describe the molecular epidemiology and resistance patterns of blaOXA-48 Klebsiella pneumoniae and Escherichia coli in Taiwan. Methods: In this multicenter surveillance study from January 2012 to August 2015, the identified blaOXA-48 ...
Ching-Hsun Wang   +6 more
doaj   +1 more source

Detection of OXA-48 Carbapenemase in the Pandemic Clone Escherichia coli O25b:H4-ST131 in the Course of Investigation of an Outbreak of OXA-48-Producing Klebsiella pneumoniae [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2012
Reports of carbapenemase producing Enterobacteriaceae (CPE) have increased dramatically in the past decade.…
Morris, D.   +8 more
openaire   +1 more source

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

open access: yesChemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato   +3 more
wiley   +1 more source

Heterogeneous hydrolytic features for OXA-48-like β-lactamases [PDF]

open access: yes, 2017
Objectives Carbapenem-hydrolysing class D β-lactamases of the OXA-48 type are increasingly reported from Enterobacteriaceae. β-Lactamase OXA-48 hydrolyses penicillins very efficiently, but carbapenems only weakly and spares broad-spectrum cephalosporins.
Oueslati, Saoussen   +2 more
core  

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