Results 71 to 80 of about 30,220 (240)
Chemistry – A European Journal, EarlyView.A straightforward one‐step protocol enables the synthesis of bio‐based and biologically active isochromans through the Oxa‐Pictet cyclization involving diverse aldehydes, including vanillin in combination with lignin‐derivable homovanillyl alcohol, a prominent aromatic platform chemical obtainable via diol‐assisted fractionation of lignocellulose ...
Anjali Kottayi +6 more
wiley +1 more source
Frontiers in Microbiology, 2021 Purpose: To investigate the susceptibility of carbapenemase-producing Enterobacterales (CPE) to mecillinam based on the recently updated European Committee on Antimicrobial Susceptibility Testing (EUCAST) breakpoints for uncomplicated Urinary Tract ...
Frieder Fuchs +6 more
doaj +1 more source
In vitro evaluation of dual carbapenem combinations against carbapenemase-producing Enterobacteriaceae [PDF]
, 2016 Objectives: This study aimed to analyse the in vitro activity of dual combinations of carbapenems against Klebsiella pneumoniae producing the main carbapenemase types.Methods: MIC values of the carbapenems, imipenem, meropenem, ertapenem and doripenem ...
Kieffer, Nicolas +2 more
core
Derepressed transfer properties leading to the efficient spread of the plasmid encoding carbapenemase OXA-48 [PDF]
, 2013 The current emergence of the carbapenemase OXA-48 among Enterobacteriaceae is related to the spread of a single IncL/M-type plasmid, pOXA-48a. This plasmid harbors the blaOXA-48 gene within a composite transposon, Tn1999, which is inserted into the tir ...
Nordmann, Patrice +2 more
core +3 more sources
Chromosome-mediated OXA-48 carbapenemase in highly virulent Escherichia coli [PDF]
Journal of Antimicrobial Chemotherapy, 2013 Bacteria multiresistant to antibiotics are widely supposed to be weakly virulent. However, the virulence traits of carbapenem-resistant Enterobacteriaceae have not been investigated. In this work, we investigated the virulence and resistance mechanism of an extraintestinal pathogenic Escherichia coli (ExPEC) strain (LEB15) that exhibited decreased ...
Beyrouthy, Racha +8 more
openaire +4 more sources
Photochemistry of Aromatic N‐Oxides in Water Probed by Time‐Resolved X‐ray Absorption Spectroscopy
Chemistry – A European Journal, EarlyView.Time‐resolved XAS at the nitrogen and oxygen K‐edges is applied to the photorearrangement of two N‐oxides in water. Pyridine N‐oxide rapidly forms the oxaziridine isomer. Pyridazine N‐oxide undergoes ring opening to the diazo compound, without any evidence of intermediates.
Maximilian Paradiz Domínguez +3 more
wiley +1 more source
Microbiology SpectrumInternational guidance recommends ceftazidime-avibactam for OXA-48-type carbapenemase-producing Enterobacterales (OXA-48-CPE) infections. However, OXA-48-CPE lacking extended spectrum and AmpC β-lactamases may remain susceptible to third-generation ...
Jinghao Nicholas Ngiam +4 more
doaj +1 more source
OXA-48-Mediated Ceftazidime-Avibactam Resistance Is Associated with Evolutionary Trade-Offs
mSphere, 2019 Infections due to carbapenemase-producing Gram-negative pathogens are associated with limited treatment options and consequently lead to increased mortality and morbidity.
Christopher Fröhlich +5 more
doaj +1 more source
Chemistry – A European Journal, EarlyView.In situ phenoxide formation at the benzene terminus triggers room‐temperature conversion of thia[6]helicene S,S‐dioxides to coronene. The solubility contrast drives product precipitation, enabling isolation by simple filtration. This pericyclic annulation between the helical termini provides direct access to coronene‐type planar architectures ...
Kaito Seino, Takashi Murase
wiley +1 more source
Antibiotics, 2021 Carbapenem-resistant Enterobacteriaceae (CRE), especially carbapenem-resistant Klebsiella pneumoniae (CRKP), are among the largest pathogenic threats to humans. The available antibiotic treatment options for combating CRKP are limited. Colistin-resistant
Parnrada Nulsopapon +5 more
doaj +1 more source