Results 81 to 90 of about 1,076,076 (217)

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, EarlyView.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source

Rising Threat of OXA-48 and other Carbapenemase Encoding Genes among Carbapenem Resistant Enterobacteriaceae in India

Journal of Pure and Applied Microbiology, 2020
Members of Enterobacteriaceae family are responsible for both community and hospital acquired infections. Because of development of antimicrobial resistance carbapenem has remained as last resort of drug for treatment of infections caused by these ...
Satyajeet K. Pawar, Shivaji T. Mohite, Kailash D. Datkhile, Madhavi N. Patil, Satish V. Kakade   +4 more
doaj   +1 more source

Karbapenemaz üreten klebsıella spp. Suşlarında oxa-48-lıke genlerinin araştırılması [PDF]

, 2018
06.03.2018 tarihli ve 30352 sayılı Resmi Gazetede yayımlanan “Yükseköğretim Kanunu İle Bazı Kanun Ve Kanun Hükmünde Kararnamelerde Değişiklik Yapılması Hakkında Kanun” ile 18.06.2018 tarihli “Lisansüstü Tezlerin Elektronik Ortamda Toplanması ...
Kahraman, Elmas Pınar
core  

Structural and biochemical features of OXA-517: a Carbapenem and expanded-spectrum Cephalosporin hydrolyzing OXA-48 variant

, 2023
International audienceOXA-48-producing Enterobacterales have now widely disseminated throughout the world. Several variants have now been reported, differing by just a few amino-acid substitutions or deletions, mostly in the region of the loop β5-β6.
Dabos, Laura, Raczynska, Joanna, Zavala, Agustin, Bogaerts, Pierre, Glupczynski, Youri, Peyrat, Aurélie, Glupczynski, Gerald, Girlich, Delphine, Iorga, Bogdan, Iorga, Bogdan I, Jaskólski, Mariusz, Bonnin, Remy A, Bonnin, Remy, Dortet, Laurent, Naas, Thierry, Retailleau, Pascal, Raczynska, Joanna E   +16 more
core   +1 more source

One‐Pot Gold(I)‐Catalyzed Rautenstrauch Rearrangement/Nitrosocarbonyl Hetero‐Diels–Alder Reaction Sequence for the Synthesis of α‐Hydroxylated Cyclopentenones

European Journal of Organic Chemistry, EarlyView.
The regio‐ and stereoselective synthesis of ring‐fused α‐hydroxy‐2‐cyclopentenones is achieved by a one‐pot gold(I)‐catalyzed Rautenstrauch rearrangement/nitrosocarbonyl hetero‐Diels–Alder reaction/ring opening sequence carried out on suitable propargyl esters followed by selective NO bond cleavage.
Dina Scarpi, Samuele Visi, Andrea Muzzu, Ernesto G. Occhiato   +3 more
wiley   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, EarlyView.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source

Duplex Recombinase Polymerase Amplification‐Lateral Flow Assay for Rapid Visual Detection of Critical Antibiotic Resistance Genes in Escherichia coli and Klebsiella pneumoniae From Positive Blood Cultures

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a pair of duplex RPA‐LFA assays for the simultaneous detection of critical resistance genes, blaCTX‐M/mcr‐1 and blaoxa‐48‐like/blaNDM, from hemoculture samples. Under optimized conditions, duplex RPA was performed at 37°C–38°C for 25 min, followed by LFA for 10–15 min.
Variya Nemidkanam, Pattamaporn Deechart, Nuntaree Chaichanawongsaroj   +2 more
wiley   +1 more source

Biobased Epoxidized Castor Oil Covalent Adaptable Networks Adhesives Reinforced with Recycled Carbon Fibers

Macromolecular Rapid Communications, EarlyView.
It is reported the design of biobased sustainable, smart, and functional adhesives achieved dispersing recycled carbon fibers into biobased epoxy monomer. ABSTRACT The development of sustainable, smart, and functional adhesives is crucial in advancing environmentally friendly materials.
Alberto Cellai, Rafael Turra Alarcon, Bernhard Sölle, Elisabeth Rossegger, Valentina Casalegno, Milena Salvo, Marco Sangermano   +6 more
wiley   +1 more source

Carbapenem Resistance of OXA-48 Gene Coding in Klebsiella Pneumoniae and Escherichia Coli

Annals of Mechnikov's Institute, 2021
Introduction: Bacteria that treated with antibiotics has ability to adapt or mutate due to form a defend mechanism. OXA-48 produces isolate that have ability as a resistance to drugs and all β-lactam, including cephalosporin, cephamycin, monobactone, and
Nita Parisa, Muhammad Fitrizal, Ella Amalia   +2 more
doaj  

On the Evolvability of OXA-48. A comprehensive study of new functions within the β-lactamase OXA-48

, 2021
Our understanding of how antimicrobial resistance enzymes evolve to expand their substrate spectrum is limited. OXA-48, an enzyme able to catalyse the hydrolysis of β-lactam drugs, has become one of the most successfully disseminating β-lactamases. Although OXA-48 hydrolyses penicillins with high efficiency, its activity towards oxyimino cephalosporins,
openaire   +1 more source