Results 101 to 110 of about 1,076,076 (217)

New Results From the Pre‐Pottery Neolithic Site of Al Uyaynah, Tabuk, in Northwestern Saudi Arabia

Arabian Archaeology and Epigraphy, EarlyView.
ABSTRACT Al Uyaynah is a low sandstone mound on an alluvial plain, long known for its extensive surface remains of stone‐built circular and rectangular structures. Following test excavations in 2012, more detailed excavation was undertaken in 2016 within one of the largest rectangular stone structures.
Khalid Alasmari, Stephanie F. Piper, Kirsten Grothe, W. Derek Hamilton, Delphine Joly, Penny Bickle, Geoff Bailey   +6 more
wiley   +1 more source

WGS-based characterization of trans-sectoral OXA-48-producing Escherichia coli in Switzerland

One Health Advances
The broad trans-sectoral (humans, animals, environment) dissemination potential of OXA-48 carbapenemase-producing Escherichia coli (OXA-48-Ec) and OXA-48-harboring plasmids represent a major One-Health concern.
Valentina Donà, Patrice Nordmann, Javier E. Fernandez, Laurent Poirel, Jacqueline Findlay, Simone Schuller, Sonja Kittl, Helene Rohrbach, Andrea Endimiani, Vincent Perreten   +9 more
doaj   +1 more source

Comparative evaluation of a novel chromogenic medium (chromID OXA-48) for detection of OXA-48 producing Enterobacteriaceae

, 2014
Comparative evaluation of the recently developed chromogenic culture medium chromID OXA-48 (bioMérieux) with chromID CARBA (bioMérieux) and SUPERCARBA showed that chromID OXA-48 and SUPERCARBA media have the highest sensitivity for detection of OXA-48 ...
Girlich, Delphine, Anglade, Claire, Nordmann, Patrice, Zambardi, Gilles   +3 more
core  

Molecular Detection of Oxa-48 β-lactamase in Proteus spp. causing UTI

, 2019
Antibiotic resistance of pathogenic bacteria is becoming one of the most serious problems encountered by the medical community as a result of antibiotic random use. New traits of drug resistance are continuously emerging in pathogenic bacteria due to the
Mohammed Jasim Al-Shamarti
core   +1 more source

Dealing With Inbuilt Age: A Bayesian Approach to Radiocarbon Dating of Rice, Bamboo and Charcoal From Non Ban Jak, Thailand

Archaeometry, EarlyView.
ABSTRACT New radiocarbon determinations from rice grains and bamboo have been obtained from Non Ban Jak, Northeast Thailand. These, along with charcoal, date a late Iron Age building sequence. The results come from short‐lived species and charcoal with potential inbuilt age. We built a series of Bayesian models to obtain a reliable chronology.
C. F. W. Higham, T. F. G. Higham
wiley   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source

Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism

The FEBS Journal, EarlyView.
Computational modelling and in vitro liver cell experiments indicate that medium‐chain acyl‐CoA dehydrogenase (MCAD) deficiency causes an accumulation of (especially medium‐chain) acyl‐CoAs at the cost of free CoA (CoASH). A substantial decrease in CoASH impairs flux through many pathways essential for energy homeostasis.
Ligia Akemi Kiyuna, Christoff Odendaal, Madhulika Singh, Albert Gerding, Miriam Langelaar‐Makkinje, Marianne van der Zwaag, Asmara Drachman, Vladimíra Cetkovská, Gaby Liem Foeng Kioen, Anne‐Claire M. F. Martines, Nicolette C. A. Huijkman, Hein Schepers, Bart van de Sluis, Dirk‐Jan Reijngoud, Ody C. M. Sibon, Amy C. Harms, Thomas Hankemeier, Barbara M. Bakker   +17 more
wiley   +1 more source

Aetiology and Antibiotic Susceptibility of Common Bacterial Infections in Hospitalised Patients: A 2019 Multisite Cross‐Sectional Survey in Jakarta, Indonesia

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives To describe the aetiology and antibiotic susceptibility patterns of common bacterial infections in hospitalised patients in Jakarta, Indonesia. Methods We conducted a hospital‐wide point prevalence survey in six hospitals in 2019, capturing data from routinely ordered bacterial cultures taken before the start of antibiotic treatment.
Justin de Brabander, Erni J. Nelwan, Ralalicia Limato, Monik Alamanda, Manzilina Mudia, Enty Tjoa, Ifael Y. Mauleti, Maria Mayasari, Iman Firmansyah, T. Mannaria Jayati, Michèle van Vugt, H. Rogier van Doorn, Raph L. Hamers, Erni J. Nelwan, Ralalicia Limato, Manzilina Mudia, Monik Alamanda, Helio Guterres, Enty Enty, Y. Ifael, Maria Mayasari Mauleti, Iman Firmansyah, May Hizrani, Anis Karuniawati, Taralan Tambunan, Amin Soebandrio, Decy Subekti, Iqbal Elyazar, Mutia Rahardjani, Fitria Wulandari, Reinout van Crevel, H. Rogier van Doorn, Vu Thi Lan Huong, Nga Do Ti Thuy, Sonia Lewycka, Alex Broom, Raph L. Hamers   +36 more
wiley   +1 more source

Genetic and Biochemical characterization of OXA-519, a novel OXA-48-like β-lactamase.

, 2018
A multidrug-resistant 1210 isolate with reduced carbapenem susceptibility revealed the presence of a novel plasmid-encoded gene, named The 60.7-kb plasmid (pOXA-519) was similar to the IncL-OXA-48 prototypical plasmid except for a ca.
Dabos, Laura, Daniel T. Huang, Zavala, Agustin, Bogaerts, Pierre, Youri Glupczynski, Glupczynski, Youri, Glupczynski, Gerald, Agustin Zavala, Iorga, Bogdan I, Iorga, Bogdan, Huang, Te-Din, Bonnin, Remy A, Huang, Daniel T., Bogdan I. Iorga, Laura Dabos, Sacré, Pierre-Alexandre, Naas, Thierry, Sacré, Pierre, Remy A. Bonnin, Pierre Bogaerts, Pierre Sacré, Thierry Naas   +21 more
core   +1 more source

Moderate‐Temperature Hydrothermal Treatment Removes Detectable DNA and Antibiotic Resistance Genes From Municipal Sludge While Preserving Resource Value

Water and Environment Journal, EarlyView.
This graphical abstract shows the overall study design where dewatered wastewater sludge samples were collected and subjected to a range of HT temperatures. Measurement of nucleic acid concentration and antibiotic resistance gene profiles across temperatures showed that HT at moderate temperatures offers sustainable, scalable sludge sanitation and ARG ...
R. Sean Norman, Mirza Isanovic, Gabrielle Kartzmark, Nicole Berge   +3 more
wiley   +1 more source