Results 111 to 120 of about 30,220 (240)

Moderate‐Temperature Hydrothermal Treatment Removes Detectable DNA and Antibiotic Resistance Genes From Municipal Sludge While Preserving Resource Value

Water and Environment Journal, EarlyView.
This graphical abstract shows the overall study design where dewatered wastewater sludge samples were collected and subjected to a range of HT temperatures. Measurement of nucleic acid concentration and antibiotic resistance gene profiles across temperatures showed that HT at moderate temperatures offers sustainable, scalable sludge sanitation and ARG ...
R. Sean Norman, Mirza Isanovic, Gabrielle Kartzmark, Nicole Berge   +3 more
wiley   +1 more source

WGS-based characterization of trans-sectoral OXA-48-producing Escherichia coli in Switzerland

One Health Advances
The broad trans-sectoral (humans, animals, environment) dissemination potential of OXA-48 carbapenemase-producing Escherichia coli (OXA-48-Ec) and OXA-48-harboring plasmids represent a major One-Health concern.
Valentina Donà, Patrice Nordmann, Javier E. Fernandez, Laurent Poirel, Jacqueline Findlay, Simone Schuller, Sonja Kittl, Helene Rohrbach, Andrea Endimiani, Vincent Perreten   +9 more
doaj   +1 more source

Potential of high-dose cefepime/tazobactam against multi-resistant Gram-negative pathogens [PDF]

, 2017
Background: Early β-lactamase inhibitors were combined with established penicillins, but different combinations may be more appropriate to counter current β-lactamase threats, with development facilitated by the US Generating Antibiotic Incentives Now ...
Livermore, David M, Mushtaq, Shazad, Turner, Simon J, Warner, Marina, Woodford, Neil   +4 more
core   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque, Aymeric Jacquemin, Delphine Girlich, Rémy A. Bonnin, Laurent Dortet   +4 more
wiley   +1 more source

Activity of ceftolozane/tazobactam against surveillance and ‘problem’ Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles [PDF]

, 2017
Background: We assessed the activity of ceftolozane/tazobactam against consecutive isolates collected in the BSAC Bacteraemia Surveillance from 2011 to 2015 and against ‘problem’ isolates sent to the UK national reference laboratory from July 2015, when ...
Aiysha Chaudhry, Akova, Al-Agamy, Babouee Flury, Berrazeg, Bonacorsi, Bonfiglio, Bonfiglio, Cabot, Cabot, Castón, Cavallo, Chang, Chen, Daniele Meunier, David M. Livermore, Doumith, Edelstein, Farrell, Gelfand, Hernández-Tejedor, Katie L. Hopkins, Livermore, Livermore, Livermore, Livermore, Livermore, Neil Woodford, Normark, Papp-Wallace, Papp-Wallace, Peter Staves, Poirel, Poirel, Rachael Adkin, Rachel Pike, Reynolds, Robert Hill, Shazad Mushtaq, Sousa-Dominguez, Strateva, Sucher, Vickery, Williams   +43 more
core   +1 more source

Phenotypic and Genotypic Study of Antibiotic Resistance blaPER‐1, blaVEB, and blaSHV‐1 Genes in Clinical Isolates of Pseudomonas aeruginosa

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Pseudomonas aeruginosa is a non‐fermentative, opportunistic Gram‐negative bacterium that causes 10%–15% of nosocomial and burn wound infections worldwide. This bacterium is resistant to various antibiotics through multiple mechanisms, including acquisition of resistance genes.
Milad Gholampour Matin, Reza Shapouri, Mohammadreza Nahaei, Mojtaba Mohammadi Roknabadi, Rasoul Shokri   +4 more
wiley   +1 more source

Carbapenemase-producing Enterobacteriaceae in hospital wastewater:a reservoir that may be unrelated to clinical isolates [star] [PDF]

, 2016
Summary Background: Carbapenemase-producing Enterobacteriaceae (CPE) are an emerging infection control problem in hospitals worldwide. Identifying carriers can help reduce potential spread and infections.
Cheesbrough, John, Hopkins, Katie, Meunier, Danièle, Perry, Claire L., Pickup, Roger William, Pike, Rachel, White, Leila, Wilkinson, Paul, Woodford, Neil   +8 more
core   +1 more source

Primeros aislados de Escherichia coli con carbapenemasas tipo OXA 48 en Panamá

Infectio
La OXA-48, una beta-lactamasa de clase D, posee una capacidad de diseminación muy alta, hidroliza los carbapenemicos débilmente; sin embargo, cuando se asocia con otros mecanismos de resistencia como las B-lactamasas de espectro extendido (ESBL), AmpC o ...
Olmedo Villarreal
doaj   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source