Results 1 to 10 of about 22,786,144 (157)

OXA-484, an OXA-48-Type Carbapenem-Hydrolyzing Class D β-Lactamase From Escherichia coli

Frontiers in Microbiology, 2021
OXA-48-like carbapenemases are among the most frequent carbapenemases in Gram-negative Enterobacterales worldwide with the highest prevalence in the Middle East, North Africa and Europe.
Stephan Göttig, Volkhard Kempf, Janko Sattler   +2 more
exaly   +4 more sources

Molecular, Genetic, and Biochemical Characterization of OXA-484 Carbapenemase, a Difficult-to-Detect R214G Variant of OXA-181 [PDF]

Microorganisms
OXA-244, an R214G variant of OXA-48, is silently spreading worldwide likely because of difficulties in detection using classical screening media. Here, we characterized two clinical isolates of Escherichia coli and Citrobacter youngae that displayed ...
Camille Gonzalez, Saoussen Oueslati, Mariam Rima, Réva Nermont, Laurent Dortet, Katie L. Hopkins, Bogdan I. Iorga, Rémy A. Bonnin, Thierry Naas   +8 more
doaj   +3 more sources

First Report of OXA-181-Producing Enterobacterales Isolates in Latin America [PDF]

Microbiology Spectrum, 2023
We characterized five carbapenemase-producing Enterobacterales (CPE) isolates from two health care institutions in Lima, Peru. The isolates were identified as Klebsiella pneumoniae (n = 3), Citrobacter portucalensis (n = 1), and Escherichia coli (n = 1).
Diego Cuicapuza, Luis Alvarado, Norah Tocasca, Daniel Aguilar, Juan Carlos Gómez-de-la-Torre, Guillermo Salvatierra, Pablo Tsukayama, Jesús Tamariz   +7 more
doaj   +4 more sources

Characterization of the First Carbapenem-Resistant Pseudocitrobacter faecalis Harboring bla_OXA-181 in China [PDF]

Antibiotics, 2022
With the wide use of carbapenems, carbapenem-resistant Enterobacterales have been increasingly reported worldwide. In this study, one blaOXA-181-positive Pseudocitrobacter faecalis strain was isolated from the blood culture of a patient with a ...
Qingyu Shi, Yan Guo, Yang Yang, Shi Wu, Renru Han, Li Ding, Dandan Yin, Fupin Hu   +7 more
doaj   +3 more sources

The hazard of carbapenemase (OXA-181)-producing Escherichia coli spreading in pig and veal calf holdings in Italy in the genomics era: Risk of spill over and spill back between humans and animals [PDF]

Frontiers in Microbiology, 2022
Carbapenemase-producing Enterobacterales (CPE) are considered a major public health issue. In the frame of the EU Harmonized AMR Monitoring program conducted in Italy in 2021, 21 epidemiological units of fattening pigs (6.98%; 95% CI 4.37–10.47%; 21/301)
Virginia Carfora, Elena Lavinia Diaconu, Angela Ianzano, Paola Di Matteo, Roberta Amoruso, Elena Dell'Aira, Luigi Sorbara, Francesco Bottoni, Flavia Guarneri, Laura Campana, Alessia Franco, Patricia Alba, Antonio Battisti   +12 more
doaj   +2 more sources

In silico characterization of IncX3 plasmids carrying blaOXA-181 in Enterobacterales [PDF]

Frontiers in Cellular and Infection Microbiology, 2022
Carbapenem-resistant Enterobacterales poses a global urgent antibiotic resistance threat because of its ability to transfer carbapenemase genes to other bacteria via horizontal gene transfer mediated by mobile genetic elements such as plasmids ...
Zhijian Yu, Zhengrong Zhang, Lile Shi, Shengni Hua, Ting Luan, Qiuping Lin, Zhixiong Zheng, Xiaosan Feng, Mubiao Liu, Xiaobin Li   +9 more
doaj   +2 more sources

Klebsiella Species and Enterobacter cloacae Isolates Harboring blaOXA-181 and blaOXA-48: Resistome, Fitness Cost, and Plasmid Stability [PDF]

Microbiology Spectrum, 2022
IncX3 and IncL plasmids have been named as catalysts advancing dissemination of blaOXA-181 and blaOXA-48 genes. However, their impact on the performance of host cells is vastly understudied. Genetic characteristics of blaOXA-48- and blaOXA-181-containing
Samiratu Mahazu, Isaac Prah, Yusuke Ota, Takaya Hayashi, Yoko Nukui, Masato Suzuki, Yoshihiko Hoshino, Yukihiro Akeda, Toshihiko Suzuki, Tomoko Ishino, Anthony Ablordey, Ryoichi Saito   +11 more
doaj   +2 more sources

Detection of OXA-181 Carbapenemase in Shigella flexneri [PDF]

Emerging Infectious Diseases
We report the detection of OXA-181 carbapenemase in an azithromycin-resistant Shigella spp. bacteria in an immunocompromised patient. The emergence of OXA-181 in Shigella spp.
Ghulam Dhabaan, Hassan Jamal, Danielle Ouellette, Sarah Alexander, Karen Arane, Aaron Campigotto, Manal Tadros, Pierre-Philippe Piché-Renaud   +7 more
doaj   +2 more sources

Emergence and characterization of new OXA-181 variants in France: OXA-1181, OXA-1201, OXA-1205, OXA-1207, and OXA-1226 [PDF]

Microbiology Spectrum
Since 2022, the diversity of OXA-48 variants has increased in France. We analyzed the dissemination of five recent variants (OXA-1181, OXA-1201, OXA-1205, OXA-1207, and OXA-1226) mostly identified on plasmids in high-risk Escherichia coli clones.
Léa Bientz, Réva Nermont, Cécile Emeraud, Thierry Naas, Rémy A. Bonnin, Laurent Dortet   +5 more
doaj   +2 more sources

Coexistence of bla NDM−1, bla IMP−4and bla OXA−181 in Citrobacter braakii clinical isolate in China [PDF]

BMC Microbiology
Background Citrobacter braakii (C. braakii) is a gram-negative bacterium associated with hospital-acquired infections such as respiratory tract infections and bacteremia. There has been a gradual increase in the number of C.
Shanshan Wang, Jiao Zhang, Bingjie Wang, Ying Zhou, Weihua Han, Xiaocui Wu, Yanlei Xu, Fangyou Yu, Huilin Zhao   +8 more
doaj   +2 more sources