Results 1 to 10 of about 15,864 (174)

Revealing sRNA expression profiles of NDM-5-producing CRKP and explore the role of sRNA207 in NDM-5-producing CRKP resistance [PDF]

Microbiology Spectrum
New Delhi metallo-beta-lactamase-5 (NDM-5)-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) is characterized by high virulence, high morbidity, and mortality, and the detection rate in children has increased in recent years.
Chonghong Xie, Yibo Bai, Yan Li, Bing Cui, Guixue Cheng, Jianhua Liu, Yong liu, Xiaosong Qin   +7 more
doaj   +4 more sources

Analysis of the hypovirulent Klebsiella pneumoniae with the NDM-5 gene on IncN plasmids [PDF]

Microbiology Spectrum
Our study aims to analyze the hypovirulent Klebsiella pneumoniae with the NDM-5 gene on IncN plasmids. This strain was isolated from a patient with a liver abscess, and the ST type was ST147.
Jianhua Fang, Guoyu Wang, Xiuhua Kang, Zhenhui Pan, Yanfang Mei, Huade Chen, Yang Liu, Tianxin Xiang   +7 more
doaj   +4 more sources

Occurrence and characterization of NDM-5-producing Escherichia coli from retail eggs. [PDF]

Front Microbiol, 2023
The New Delhi Metallo-β-lactamase (NDM) producing Enterobacterales has been detected from diverse sources but has rarely been reported in retail eggs. In this study, 144 eggshell and 96 egg content samples were collected in 2022 from Guangdong province and were screened for NDM-producing strains. Four Escherichia coli strains (ST3014, ST10, ST1485, and
Liu YY, Li T, Yue H, Yue C, Lu L, Chen J, Deng H, Gao X, Liu JH.   +8 more
europepmc   +4 more sources

Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China. [PDF]

Infect Drug Resist
The global dissemination of carbapenem-resistant Enterobacteriaceae poses a significant threat to public health. In this study, we identified two clinical Klebsiella isolates, K. quasipneumoniae ACESH02628 and K. pneumoniae ACESH02857, harboring the bla NDM-5 gene in China.
Chen L, Liu R, Ye H, Qian J, Lou D.
europepmc   +4 more sources

NDM-5-carried outer membrane vesicles impair the efficacy of antibiotics against bacterial infections. [PDF]

Antimicrob Agents Chemother
ABSTRACT The intensifying use of antimicrobials in the rapidly growing livestock industry has heightened concerns over the proliferation of antibiotic resistance, particularly among Enterobacteriaceae producing β-lactamase.
Li L, Zhang Y, Weng L, Ji Q, Gao F, Yang S, Fu L, Gao Y, Ma X, Zhang M, Xu Q, Wu Y, Qu S.   +12 more
europepmc   +3 more sources

Genomic Epidemiologic Investigation of a Multispecies Hospital Outbreak of NDM-5-Producing Enterobacterales Infections

, 2023
ABSTRACTBackgroundNew Delhi metallo-β-lactamase (NDM) represents an emergent mechanism of carbapenem resistance associated with high mortality and limited antimicrobial treatment options. Because theblaNDMresistance gene is often carried on plasmids, traditional infection prevention and control (IP&C) surveillance methods like speciation ...
Raabe NJ, Valek AL, Griffith MP, Mills E, Waggle K, Srinivasa VR, Ayres AM, Bradford C, Creager H, Pless LL, Sundermann AJ, Tyne DV, Snyder GM, Harrison LH.   +13 more
europepmc   +3 more sources

Emergence of NDM-5-Producing Escherichia coli in a Teaching Hospital in Chongqing, China: IncF-Type Plasmids May Contribute to the Prevalence of blaNDM–5 [PDF]

Frontiers in Microbiology, 2020
The newly emerging NDM-5 confers increased antibiotic resistance and attracts extensive global attention, but the prevalence, dissemination mechanism, and clinical significance of NDM-5 among clinical Escherichia coli (E.
Hua Zou, Xiaojiong Jia, Hang Liu, Shuang Li, Xianan Wu, Shifeng Huang   +5 more
doaj   +3 more sources

Draft genome sequence of NDM-5, CMY-42 carrying carbapenem-resistant Escherichia coli. [PDF]

Microbiol Resour Announc
ABSTRACT We report the draft genome sequence of carbapenem-resistant Escherichia coli (CREC-1) of sequence type (ST2083) isolated from a urine sample of a 2-year-old female toddler carrying antimicrobial resistance genes blaNDM-5 and blaCMY-42 which displays ...
Mudaliar Y, Kalaikumari S S, M N, N B MR, Raj M, J M, Elangovan E, Perumal K.   +7 more
europepmc   +3 more sources

Successful termination of a multi-year wastewater-associated outbreak of NDM-5-carrying E. coli in a hemato-oncological center [PDF]

Antimicrobial Resistance and Infection Control
Background In May 2018, an outbreak of NDM-5-carrying Escherichia coli (NDM-5-EC) was detected at the hemato-oncology department of a tertiary care center in Austria.
Heidrun Kerschner, Linda Jernej, Adriana Cabal, Patrick Hyden, Sigrid Machherndl-Spandl, Lucia Berning, Anna Blaimschein, Werner Ruppitsch, Petra Apfalter, Rainer Hartl   +9 more
doaj   +2 more sources

The effects of NDM-5 on Escherichia coli and the screening of interacting proteins. [PDF]

Front Microbiol
Carbapenem-resistant Escherichia coli (E. coli) strains are widely distributed and spreading rapidly, creating significant challenges for clinical therapeutics. NDM-5, a novel mutant of New Delhi Metallo-β-Lactamase-1 (NDM-1), exhibits high hydrolase activity toward carbapenems.
Li L, Gao Y, Wang L, Lu F, Ji Q, Zhang Y, Yang S, Cheng P, Sun F, Qu S.   +9 more
europepmc   +4 more sources