Results 31 to 40 of about 79,016,594 (203)

Emergence of a High-Risk Klebsiella michiganensis Clone Disseminating Carbapenemase Genes

Frontiers in Microbiology, 2022
Klebsiella michiganensis is emerging as an important human pathogen of concern especially strains with plasmid-mediated carbapenemase genes. The IncX3-blaNDM-5 plasmid has been described as the primary vector for blaNDM-5 dissemination.
Isaac Prah, Isaac Prah, Yoko Nukui, Yoko Nukui, Shoji Yamaoka, Ryoichi Saito, Ryoichi Saito   +6 more
doaj   +1 more source

Occurrence of Aztreonam-Avibactam-Resistant NDM-5-Producing Escherichia coli in the Food Chain

Antimicrobial Agents and Chemotherapy, 2021
Among the most common metallo-β-lactamases (MBL), the most clinically significant are the New Delhi Metallo-β-lactamases (NDM). NDM enzymes hydrolyze almost all β-lactams except aztreonam and are not inhibited by novel β-lactamase inhibitors such as avibactam (AVI), relebactam, and vaborbactam (1).….
Mustafa Sadek, Laurent Poirel, Patrice Nordmann   +2 more
openaire   +3 more sources

Diversity of New Delhi metallo-beta-lactamase-producing bacteria in China

International Journal of Infectious Diseases, 2017
Objectives: The prevalence and dissemination of diverse NDM-producing bacteria in China was investigated. Methods: We collected 1,162 isolates from 8 cities during December 2013 ∼ May 2015 in China.
Xiaofeng Hu, Xuebing Xu, Xu Wang, Wencheng Xue, Haijian Zhou, Ling Zhang, Qiuxia Ma, Rongtao Zhao, Guozheng Li, Peng Li, Chuanfu Zhang, Yun Shi, Jian Wang, Leili Jia, Rongzhang Hao, Ligui Wang, Dayang Zou, Xuelin Liu, Shaofu Qiu, Hongbin Song, Yansong Sun   +20 more
doaj   +1 more source

NDM-5-carried outer membrane vesicles impair the efficacy of antibiotics against bacterial infections. [PDF]

Antimicrob Agents Chemother
ABSTRACT The intensifying use of antimicrobials in the rapidly growing livestock industry has heightened concerns over the proliferation of antibiotic resistance, particularly among Enterobacteriaceae producing β-lactamase.
Li L, Zhang Y, Weng L, Ji Q, Gao F, Yang S, Fu L, Gao Y, Ma X, Zhang M, Xu Q, Wu Y, Qu S.   +12 more
europepmc   +3 more sources

Molecular eidemiology of carbapenem-resistant Enterobacter cloacae complex in a tertiary hospital in Shandong, China

BMC Microbiology, 2023
Background The increasing incidence and prevalence of carbapenem-resistant Enterobacter cloacae complex (CREC) poses great challenges to infection prevention and disease treatment.
Shengnan Hu, Wenyan Xie, Qiwen Cheng, Xiaoning Zhang, Xiutao Dong, Huaiqi Jing, Jiazheng Wang   +6 more
doaj   +1 more source

Genomic Epidemiologic Investigation of a Multispecies Hospital Outbreak of NDM-5-Producing Enterobacterales Infections

, 2023
ABSTRACT Background New Delhi metallo-β-lactamase (NDM) represents an emergent mechanism of carbapenem resistance associated with high mortality and limited antimicrobial treatment options. Because the bla NDM resistance
Raabe NJ, Valek AL, Griffith MP, Mills E, Waggle K, Srinivasa VR, Ayres AM, Bradford C, Creager H, Pless LL, Sundermann AJ, Tyne DV, Snyder GM, Harrison LH.   +13 more
europepmc   +3 more sources

Recombination of plasmids in a carbapenem-resistant NDM-5-producing clinical Escherichia coli isolate [PDF]

Journal of Antimicrobial Chemotherapy, 2018
To investigate the genetic features of five plasmids recovered from an NDM-5-producing clinical Escherichia coli strain, BJ114, and to characterize the plasmid recombination event that occurred during the conjugation process.The genetic profiles of the five plasmids were determined by PCR, conjugation, S1-PFGE, Southern hybridization and WGS analysis ...
Miaomiao, Xie, Ruichao, Li, Zhonghua, Liu, Edward Wai Chi, Chan, Sheng, Chen   +4 more
openaire   +2 more sources

Emergence of NDM-5 Producing Carbapenem-Resistant Klebsiella aerogenes in a Pediatric Hospital in Shanghai, China [PDF]

Frontiers in Public Health, 2021
Background: Carbapenem-resistant Klebsiella aerogenes (CRKA) has posed a serious threat for clinical anti-infective therapy. However, the molecular characteristics of CRKA in Shanghai are rarely reported.Objective: This study aimed to investigate the resistance profiles, dissemination mechanism, and molecular characteristics of CRKA strains isolated ...
Fen Pan, Qi Xu, Hong Zhang
openaire   +3 more sources

Detection and Genomic Characterization of a Morganella morganii Isolate From China That Produces NDM-5 [PDF]

Frontiers in Microbiology, 2019
The increasing prevalence and transmission of the carbapenem resistance gene bla NDM-5 has led to a severe threat to public health. So far, bla NDM-5 has been widely detected in various species of Enterobacterales and different hosts across various cities. However, there is no report on the bla NDM-5- harboring Morganella morganii. In January 2016, the
Xiaobing Guo, Yuting Rao, Yuting Rao, Lihua Guo, Hao Xu, Tao Lv, Xiao Yu, Yunbo Chen, Na Liu, Huiming Han, Huiming Han, Beiwen Zheng   +11 more
openaire   +3 more sources

Characterization of NDM-5 Carbapenemase-Encoding Gene (blaNDM-5) – Positive Multidrug Resistant Commensal Escherichia coli from Diarrheal Patients

Infection and Drug Resistance, 2022
The multidrug resistance Enterobacteriaceae cause many serious infections resulting in prolonged hospitalization, increased treatment charges and mortality rate. In this study, we characterized bla NDM-5-positive multidrug resistance commensal Escherichia coli (CE) isolated from diarrheal patients in Kolkata, India.Three CE strains were isolated from ...
Goutam Chowdhury, Thandavarayan Ramamurthy, Bhabatosh Das, Debjani Ghosh, Keinosuke Okamoto, Shin-ichi Miyoshi, Shanta Dutta, Asish K Mukhopadhyay   +7 more
openaire   +4 more sources