Results 11 to 20 of about 15,864 (174)

NDM-5-Producing Escherichia coli Co-Harboring mcr-1 Gene in Companion Animals in China

Animals, 2022
Carbapenem and colistin are important antibiotics for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. Here, we isolated the blaNDM-5-harboring Escherichia coli in companion animals in healthy or diseased companion ...
Xu Kuang, Runshi Yang, Xinqing Ye, Jian Sun, Xiaoping Liao, Yahong Liu, Yang Yu   +6 more
doaj   +3 more sources

Characterization of a Novel NDM-5-Harboring Plasmid from a Carbapenem-Resistant Escherichia coli Isolate from China

Infection and Drug Resistance, 2020
Dongdong Yin,1,2,* Yanfeng Lin,1,3,* Zhonghong Li,1,4,* Hui Ma,5,* Lanfen Lu,6 Kaiying Wang,1,3 Lang Yang,1,3 Xinying Du,1 Peng Li,1 Kezong Qi,2 Hongbin Song1,* 1Center for Disease Control and Prevention of PLA, Beijing, People’s Republic of China;
Yin D, Lin Y, Li Z, Ma H, Lu L, Wang K, Yang L, Du X, Li P, Qi K, Song H   +10 more
doaj   +4 more sources

Real-time genomic epidemiologic investigation of a multispecies plasmid-associated hospital outbreak of NDM-5-producing Enterobacterales infections [PDF]

International Journal of Infectious Diseases
: Objectives: New Delhi metallo-β-lactamase (NDM) is an emergent mechanism of carbapenem resistance associated with high mortality and limited treatment options.
Nathan J. Raabe, Abby L. Valek, Marissa P. Griffith, Emma Mills, Kady Waggle, Vatsala Rangachar Srinivasa, Ashley M. Ayres, Claire Bradford, Hannah M. Creager, Lora L. Pless, Alexander J. Sundermann, Daria Van Tyne, Graham M. Snyder, Lee H. Harrison   +13 more
doaj   +2 more sources

Molecular characterization and comparison of bla NDM-1-carrying and bla NDM-5-harboring IncX3-type plasmids in carbapenem-resistant Klebsiella pneumoniae

Microbiology Spectrum, 2023
Carbapenem-resistant Klebsiella pneumoniae (CRKP), which harbors the bla NDM plasmid, has been reported extensively and is considered a global threat clinically.
Yunxing Yang, Haiyang Liu, Lingxia Chen, Minjie Mao, Xiaofan Zhang, Longjie Zhou, Darong Duan, Xi Li, Hua Zhou   +8 more
doaj   +1 more source

Genetic and phenotypic characterizations of IncX3 plasmids harboring bla NDM-5 and bla NDM-16b in Japan

Microbiology Spectrum, 2023
The spread of the gene encoding the NDM-type carbapenemase, bla NDM, poses a serious threat to clinical practice and public health. This gene is usually carried by transferable plasmids, which facilitates its rapid spread among various species of ...
Hui Zuo, Yo Sugawara, Shizuo Kayama, Sayoko Kawakami, Koji Yahara, Motoyuki Sugai   +5 more
doaj   +1 more source

Characterization of NDM-5 Carbapenemase-Encoding Gene (blaNDM-5) – Positive Multidrug Resistant Commensal Escherichia coli from Diarrheal Patients

Infection and Drug Resistance, 2022
The multidrug resistance Enterobacteriaceae cause many serious infections resulting in prolonged hospitalization, increased treatment charges and mortality rate. In this study, we characterized bla NDM-5-positive multidrug resistance commensal Escherichia coli (CE) isolated from diarrheal patients in Kolkata, India.Three CE strains were isolated from ...
Goutam Chowdhury, Thandavarayan Ramamurthy, Bhabatosh Das, Debjani Ghosh, Keinosuke Okamoto, Shin-ichi Miyoshi, Shanta Dutta, Asish K Mukhopadhyay   +7 more
openaire   +4 more sources

Multiple NDM-5-Expressing Escherichia Coli Isolates From an Immunocompromised Pediatric Host [PDF]

Open Forum Infectious Diseases, 2020
Abstract Background Genes conferring carbapenem resistance have disseminated worldwide among Gram-negative bacteria. Here we present longitudinal changes in clinically obtained Escherichia coli isolates from 1 immunocompromised pediatric patient.
Flerlage, Tim, Brazelton de Cardenas, Jessica N, Garner, Cherilyn D, Hasan, Nur A, Karathia, Hiren, Qudeimat, Amr, Maron, Gabriela, Hayden, Randall   +7 more
openaire   +2 more sources

E152A substitution drastically affects NDM-5 activity [PDF]

FEMS Microbiology Letters, 2017
New Delhi Metallo beta-lactamase (NDM) is of significant public health concern due to its enormous potential to hydrolyse all major beta-lactams including carbapenems. Amino acid substitutions outside the active site reportedly affect NDM beta-lactamase activities.
Gaurav, Kumar, Bagre, Issa, Debasish, Kar, Sarmistha, Biswal, Anindya S, Ghosh   +4 more
openaire   +2 more sources

Report and Comparative Genomics of an NDM-5-Producing Escherichia coli in a Portuguese Hospital: Complex Class 1 Integrons as Important Players in bla_NDM Spread

Microorganisms, 2022
Background: New Delhi metallo-beta-lactamase (NDM) has been spreading across the globe, but the causes of its success are poorly understood. We characterized a blaNDM-5-positive Escherichia coli strain from a Portuguese hospital and conducted comparative
Rafael D. S. Tavares, Marta Tacão, Elmano Ramalheira, Sónia Ferreira, Isabel Henriques   +4 more
doaj   +1 more source

Emergence of an NDM-5-producing clinical Escherichia coli isolate in Egypt [PDF]

International Journal of Infectious Diseases, 2016
The first occurrence of New Delhi metallo-β-lactamase 5 (NDM-5), carried on an IncI1-Iγ-type plasmid of >93kb in a multidrug-resistant Escherichia coli strain in Kafr El-Sheikh, Egypt, is reported. The strain was isolated from a wound pus swab from a patient diagnosed with a fracture of the right femur. This E.
Ahmed M. Soliman, Hazim O. Khalifa, Ashraf M. Ahmed, Toshi Shimamoto, Tadashi Shimamoto   +4 more
openaire   +3 more sources