Genome Characteristic of NDM-5-Producing Klebsiella Quasipneumoniae and Klebsiella Pneumoniae in China. [PDF]
The global dissemination of carbapenem-resistant Enterobacteriaceae poses a significant threat to public health. In this study, we identified two clinical Klebsiella isolates, K. quasipneumoniae ACESH02628 and K. pneumoniae ACESH02857, harboring the bla NDM-5 gene in China.
Chen L, Liu R, Ye H, Qian J, Lou D.
europepmc +5 more sources
Spread of NDM-5 and OXA-181 Carbapenemase-Producing Escherichia coli in Chad [PDF]
We detected for the first time bla NDM-5 and bla OXA-181 in Escherichia coli isolates from hospitalized patients and healthy volunteers in Chad. These resistance genes were located on IncX3 and IncF plasmids. Despite the large diversity of
Ouchar Mahamat, Oumar +14 more
openaire +6 more sources
The effects of NDM-5 on Escherichia coli and the screening of interacting proteins. [PDF]
Carbapenem-resistant Escherichia coli (E. coli) strains are widely distributed and spreading rapidly, creating significant challenges for clinical therapeutics. NDM-5, a novel mutant of New Delhi Metallo-β-Lactamase-1 (NDM-1), exhibits high hydrolase activity toward carbapenems.
Li L +9 more
europepmc +4 more sources
E152A substitution drastically affects NDM-5 activity [PDF]
New Delhi Metallo beta-lactamase (NDM) is of significant public health concern due to its enormous potential to hydrolyse all major beta-lactams including carbapenems. Amino acid substitutions outside the active site reportedly affect NDM beta-lactamase activities.
Gaurav, Kumar +4 more
openaire +2 more sources
Emergence of an NDM-5-producing clinical Escherichia coli isolate in Egypt [PDF]
The first occurrence of New Delhi metallo-β-lactamase 5 (NDM-5), carried on an IncI1-Iγ-type plasmid of >93kb in a multidrug-resistant Escherichia coli strain in Kafr El-Sheikh, Egypt, is reported. The strain was isolated from a wound pus swab from a patient diagnosed with a fracture of the right femur. This E.
Ahmed M. Soliman +4 more
openaire +3 more sources
Multiple NDM-5-Expressing Escherichia Coli Isolates From an Immunocompromised Pediatric Host [PDF]
Abstract Background Genes conferring carbapenem resistance have disseminated worldwide among Gram-negative bacteria. Here we present longitudinal changes in clinically obtained Escherichia coli isolates from 1 immunocompromised pediatric patient.
Flerlage, Tim +7 more
openaire +2 more sources
Emergence of NDM-5-producing Escherichia coli sequence type 167 clone in Italy [PDF]
The emergence of carbapenemase-producing Enterobacteriaceae (CPE) is a critical concern worldwide. In Italy, CPE isolates are very frequent, with the KPC enzyme types strongly predominant whereas the New Delhi metallo-β-lactamase (NDM) enzymes are extremely rare.
Giufrè M +9 more
openaire +3 more sources
egemenimre/ccsds-ndm: Minor fix for Combined NDM output to KVN
Added proper error message to Combined NDM output to ...
Egemen Imre, Tevfik Uyar, Agit
core +1 more source
Molecular epidemiology of NDM-5-producing Escherichia coli high-risk clones identified in two Italian hospitals in 2017-2019 [PDF]
Between November 2018 and October 2019, carbapenem-resistant Enterobacterales carrying New Delhi Metallo-β-lactamase (NDM) caused one of the largest and persistent outbreaks occurred in Italy and intensified surveillance measures have been ...
Mengoni, Fabio +21 more
core +1 more source
egemenimre/ccsds-ndm: Version 2.0
This version adds KVN read / write support.
Egemen Imre
core +1 more source

