VirBR, a transcription regulator, promotes IncX3 plasmid transmission, and persistence of blaNDM-5 in zoonotic bacteria [PDF]
Nature CommunicationsIncX3 plasmids carrying the New Delhi metallo-β-lactamase-encoding gene, bla NDM-5, are rapidly spreading globally in both humans and animals. Given that carbapenems are listed on the WHO AWaRe watch group and are prohibited for use in animals, the ...
Julian Parkhill, Jianzhong Shen
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Global prevalence, characteristics, and future prospects of IncX3 plasmids: A review
Frontiers in Microbiology, 2022 IncX3 plasmids are narrow host range plasmids mostly found in Enterobacteriaceae with great conjugation ability, high stability, no fitness cost, and the ability to improve biofilm formation in their bacterial hosts.
Xiaobing Guo +6 more
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In silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years [PDF]
Frontiers in Microbiology, 2021 IncX3 plasmids are correlated with the dissemination and acquisition of carbapenem resistance in Enterobacteriaceae and have been prevalent in China over the last 10 years.
Baomo Liu +7 more
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Temperature-Regulated IncX3 Plasmid Characteristics and the Role of Plasmid-Encoded H-NS in Thermoregulation [PDF]
Frontiers in Microbiology, 2022 Carbapenem-resistant Enterobacteriaceae (CRE) are a critical public health problem worldwide. Globally, IncX3-type plasmids have emerged as the predominant vehicles carrying the metallo-β-lactamase gene blaNDM. Although blaNDM-bearing IncX3 plasmids have
Willem van Schaik
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Occurrence of Highly Conjugative IncX3 Epidemic Plasmid Carrying blaNDM in Enterobacteriaceae Isolates in Geographically Widespread Areas [PDF]
Frontiers in Microbiology, 2018 The emergence of New Delhi metallo-β-lactamase (NDM) in common enterobacterial species is a major concern for healthcare. Early reports have revealed that the spread of NDM involved diverse and heterogeneous plasmids. Recently, the involvement of a rare,
Ya Wang +2 more
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Case Report of blaNDM-7-Harboring IncX3 Plasmid in ST196 Klebsiella quasipneumoniae in China
Infection and Drug Resistance, 2022 Lin Sun,1,2,* Guiling Li,3,4,* Nan Meng,1 Zhenyu Wang,1 Hanyun Wang,1 Jing Wang,1,2 Xinan Jiao1,2 1Jiangsu Key Laboratory of Zoonosis/Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses ...
Xin-An Jiao
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Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China [PDF]
Emerging Microbes and Infections, 2012 The New Delhi metallo-β-lactamase (NDM-1) is one of the most important resistance traits in Enterobacteriaceae. We characterized nine blaNDM-1 producing Enterobacteriaceae recovered from seven patients who have recently travelled or been treated in India
Pak-Leung Ho +9 more
doaj +3 more sources
Emergence of blaSHV-12 and qnrS1 encoded on IncX3 plasmids: Changing epidemiology of extended-spectrum ß-lactamases among Enterobacterales isolated from broilers [PDF]
Journal of Global Antimicrobial Resistance, 2023 : Objectives: The occurrence of extended-spectrum ß-lactamase (ESBL)-producing Enterobacterales in broilers represents a risk to public health because of the possibility of transmission of ESBL producers and/or blaESBL genes via the food chain or within
Magdalena Nüesch-Inderbinen +5 more
doaj +3 more sources
First Report of OXA-181-Producing Enterobacterales Isolates in Latin America [PDF]
Microbiology Spectrum, 2023 We characterized five carbapenemase-producing Enterobacterales (CPE) isolates from two health care institutions in Lima, Peru. The isolates were identified as Klebsiella pneumoniae (n = 3), Citrobacter portucalensis (n = 1), and Escherichia coli (n = 1).
Diego Cuicapuza +7 more
doaj +3 more sources
First report of blaOXA-181-carrying IncX3 plasmids in multidrug-resistant Enterobacter hormaechei and Serratia nevei recovered from canine and feline opportunistic infections [PDF]
Microbiology SpectrumWhole-genome sequence analysis of six Enterobacter hormaechei and two Serratia nevei strains, using a hybrid assembly of Illumina and Oxford Nanopore Technologies sequencing, revealed the presence of the epidemic blaOXA-181-carrying IncX3 plasmids co ...
Chavin Leelapsawas +7 more
doaj +3 more sources