Temperature-Regulated IncX3 Plasmid Characteristics and the Role of Plasmid-Encoded H-NS in Thermoregulation [PDF]
Frontiers in Microbiology, 2022 Carbapenem-resistant Enterobacteriaceae (CRE) are a critical public health problem worldwide. Globally, IncX3-type plasmids have emerged as the predominant vehicles carrying the metallo-β-lactamase gene blaNDM. Although blaNDM-bearing IncX3 plasmids have
Willem van Schaik, Baomo Liu
exaly +7 more sources
Heliyon, 2023 The increase in the prevalence of carbapenem-producing Enterobacterales (CPE) is a major threat, with the New Delhi metallo-β-lactamase (NDM) enzyme-producing CPEs being one of the major causative agents of healthcare settings infections.
Sima Tokajian +2 more
exaly +6 more sources
Global Prevalence, Characteristics, and Future Prospects of IncX3 Plasmids: A Review
Frontiers in Microbiology, 2022 IncX3 plasmids are narrow host range plasmids mostly found in Enterobacteriaceae with great conjugation ability, high stability, no fitness cost, and the ability to improve biofilm formation in their bacterial hosts.
Haoyu Ge, Ruyan Chen, Xiaobing Guo
exaly +5 more sources
Microbiology Spectrum, 2022 Dissemination of blaNDM, which is carried on the IncX3 plasmid, among Enterobacterales has been reported worldwide. In particular, blaNDM-5-carrying IncX3 plasmids can spread among several hosts, facilitating their dissemination.
Yoshikazu Ishii +2 more
exaly +5 more sources
Plasmid-resolved genomics and machine learning-assisted profiling reveal Enterobacter soli as an overlooked host of a blaNDM-1-bearing IncX3 plasmid [PDF]
Frontiers in MicrobiologyBackgroundPlasmid-mediated carbapenem resistance is a major public health concern, yet the role of under-characterized Enterobacter species in carrying clinically important resistance plasmids remains insufficiently defined.
Yao Li +8 more
doaj +3 more sources
In Silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years [PDF]
Frontiers in Microbiology, 2021 IncX3 plasmids are correlated with the dissemination and acquisition of carbapenem resistance in Enterobacteriaceae and have been prevalent in China over the last 10 years.
Feifeng Li
exaly +5 more sources
Epidemic IncX3 Plasmids Spreading Carbapenemase Genes in the United Arab Emirates and Worldwide
Infection and Drug Resistance, 2019 Shaimaa F Mouftah,1,* Tibor Pál,1,* Dania Darwish,1 Akela Ghazawi,1 Laura Villa,2 Alessandra Carattoli,3 Ágnes Sonnevend1,41Department of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab ...
Tibor Pal +2 more
exaly +9 more sources
First Indian Report of IncX3 Plasmid Carrying blaNDM-7 in Escherichia coli From Bloodstream Infection: Potential for Rapid Dissemination [PDF]
New Microbes and New Infections, 2017 Enterobacteriaceae with blaNDM-7 is only infrequently observed. Self-transmissible plasmids carrying the blaNDM gene increase the dissemination of carbapenem resistance in developing countries.
Balaji Veeraraghavan
exaly +4 more sources
Cross-species transmission of blaNDM-5-IncX3 plasmids: molecular mechanisms and One Health-based strategies for CREC control [PDF]
Frontiers in Cellular and Infection MicrobiologyCarbapenem-resistant Escherichia coli (CREC) has emerged as a critical global health concern, particularly strains carrying the blaNDM-5-IncX3 plasmid.
Benjin Xu +9 more
doaj +5 more sources
Microbiology Spectrum, 2023 The spread of the gene encoding the NDM-type carbapenemase, bla NDM, poses a serious threat to clinical practice and public health. This gene is usually carried by transferable plasmids, which facilitates its rapid spread among various species of ...
Motoyuki Sugai +2 more
exaly +5 more sources